Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024141 (
systemic lupus erythematosus
)
44,322
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Almost all
complement component 9
(C9) deficiency in Japan shows Arg95 Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with
SLE
to elucidate the association of
SLE
and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between
SLE
patients and controls. Thus, C9 deficiency is not implicated in
SLE
susceptibility.
Lupus
2000
PMID:Complement component 9 deficiency is not a susceptibility factor for SLE. 1098 51
