Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024141 (
systemic lupus erythematosus
)
44,322
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The activity of selected lysosomal hydrolases ( (beta-galactosidase, beta-N-acetylglucosaminidase, beta-xylosidase, alpha-mannosidase,
alpha-fucosidase
) was determined in the blood serum of patients with
systemic lupus erythematosus
(
SLE
). An increased activity of all the enzymes studied was found as compared to control subjects. Presumable mechanisms of the observed changes are discussed. It is suggested that the studied enzymes may be responsible for the desintegration of the connective tissue ground substance in
SLE
.
...
PMID:Studies on the activity of selected lysosomal exoglycosidases in patients with systemic lupus erythematosus. 643 58
