Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024141 (
systemic lupus erythematosus
)
44,322
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
BACKGROUND:
Systemic lupus erythematosus
(
SLE
) is a chronic autoimmune disease characterized by multisystem involvement. Clinical management of this condition has unique aeromedical considerations and an impact on subsequent aeromedical disposition. A comprehensive decision matrix would greatly benefit aviation medicine practitioners in the management of aircrew and personnel in flying-related vocations who are diagnosed with
SLE
.
CASE REPORT:
We describe the aeromedical management of a military air traffic controller who was diagnosed with
SLE
after presenting with cutaneous
lupus
, nonscarring alopecia, symmetrical small joint polyarthropathy, leukopenia, and presence of
SLE
-specific antibody. She was treated with hydroxychloroquine and low-dose systemic glucocorticoids, and allowed to return to duties with a proximity restriction and a bar on field deployments and night duties.
DISCUSSION:
Several
SLE
manifestations may have either incapacitating or distracting effects on aircrew and personnel in flying-related vocations. Some medications used in the treatment of
SLE
may similarly impact on an individuals ability to safely execute flight or air traffic control duties. We propose an aeromedical disposition decision flowchart that would guide aviation medicine practitioners in the management of individuals diagnosed with
SLE
to ensure optimal and safe performance in their respective occupational settings.
Seah
BZQ
, Chua CG.
A proposed aeromedical disposition flowchart for
systemic lupus erythematosus
. Aerosp Med Hum Perform. 2020; 91(10):826832.
...
PMID:A Proposed Aeromedical Disposition Flowchart for Systemic Lupus Erythematosus. 3318 71
