Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024141 (systemic lupus erythematosus)
44,322 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To determine whether pulmonary blood flow is altered by cold stimulation of the mouth, a cold stimulus was induced by having 11 systemic lupus erythematosus patients without pulmonary fibrosis hold ice in their mouths. Lung perfusion was measured by continuous venous infusion of Krypton-81m. During the period in which the ice was held in the mouth, 2 patients showed 32% and 41% increase in pulmonary blood flow. After the cold stimulus was removed, pulmonary blood flow recovered in these patients to within the control range by a margin commensurate with the increase in the duration of the cold stimulus, suggesting that the response may be due to an abnormal reflex of the autonomic nervous system.
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PMID:Increase in pulmonary blood flow during cold stimulation of the mouth in patients with systemic lupus erythematosus. 249 Feb 68