Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024141 (systemic lupus erythematosus)
 44,322 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 25 cases of pregnancy complicated by SLE, we examined the relationships between fetal growth and histopathological findings in the placental villi. The following results were obtained. 1. As for histological findings in the placenta, in most cases clear findings of circulatory disorders were obtained. 2. In the light microscopic visual field at x63, no difference was observed among the group in the cross section occupying rate of the villi and cross section area of the terminal villi, but in one case in the IUFD group, the villi were underdeveloped and the cross section occupying rate of the villi was low. 3. The villous/vascular cross section area ratio per single terminal villus became smaller in the following order: full term AFD group, full term SFD group, premature AFD group, and premature SFD group, and a significant difference was observed between the normal controls and the premature SFD group. 4. During immunoglobulin staining by the PAP method, IgG deposits were observed in the villous syncytiotrophoblasts and their periphery, in vascular endothelial cells in the villi, and in the villous interstitium, etc. in both the SLE cases and the normal controls, but deposits of IgM in the same regions were observed only in the premature SFD group of pregnancies complicated by SLE.
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PMID:[Morphological and immunohistochemical study of the placental villi in pregnancy complicated by systemic lupus erythematosus]. 160 75

Fetal heart rate response to fetal acoustic stimulation (FAST) during the antepartum period after 25 weeks of gestational age was studied in 157 cases of normal pregnancy, 22 cases of fetal distress, 12 cases of SFD, 10 cases of fetal malformation, 9 cases of placental dysfunction, 4 cases of oligohydramnios, 12 cases of toxemia of pregnancy, and 15 cases of SLE. Five different types of response were observed: Type I through type V. 1. FAST was available to evaluate fetal well-being from 27 weeks of gestational age, although a nonstress test (NST) has been used after 31 weeks of gestational age. 2. Type IV was observed frequently in the case of coiling of the umbilical cord. 3. In acute fetal distress abnormality was detected by NST prior to FAST, but in latent fetal distress abnormality was detected by FAST prior to NST. 4. Cases classified as FAST types III and IV, which remained unchanged or deteriorated to III, IV or V were almost all characterized by poor fetal outcome.
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PMID:[Fetal heart rate patterns in response to acoustic stimulation]. 194 May 54