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Query: UMLS:C0024141 (
systemic lupus erythematosus
)
44,322
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 50-year-old woman with
systemic lupus erythematosus
was admitted in an obtunded state. An EEG recorded while she was unconscious demonstrated one episode of rhythmic sharp wave activity in the left occipital area that lasted for 5 minutes and was followed later in the same recording by an episode of high amplitude sharp wave discharges in the right posterior temporal and occipital areas. When the patient regained consciousness, she had an
Anton's syndrome
of cortical blindness with denial. When she recovered light perception only, the EEG demonstrated synchronous and independent right and left occipital-posterior temporal periodic lateralized epileptiform discharges (PLEDs). Cortical blindness (
Anton's syndrome
) associated with abnormal electrical activity in the occipital areas has only rarely been reported. Our case is significant for the following reasons: 1) PLEDs maximal right and left occipital areas associated with bilateral visual loss has not previously been observed; 2) abnormal electrical activity in the occipital lobes may be a reversible cause of
Anton's syndrome
.
...
PMID:Reversible cortical blindness (Anton's syndrome) associated with bilateral occipital EEG abnormalities. 233 39
Although the neuropathologic findings in patients who have died of
systemic lupus erythematosus
(
SLE
) are well documented, the cytomorphologic reactions present in the cerebrospinal fluid (CSF) of living patients with transient neurologic disturbances associated with
SLE
are poorly understood. Short of brain biopsy, a CSF cytomorphologic examination may provide the best clue to the nature of the cellular inflammatory process in these transient CNS disorders. Cells in the CSF from a patient with
SLE
who developed transient cortical blindness with denial of visual loss (
Anton's syndrome
) were subjected to detailed morphologic classification. The findings suggest that tissue destruction and subclinical hemorrhage can be confirmed by careful CSF cytologic examination in patients with these transient neurologic disturbances.
...
PMID:Cerebrospinal fluid cytomorphology in systemic lupus erythematosus with Anton's syndrome. 695 9
