Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024141 (systemic lupus erythematosus)
 44,322 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Manic-depressive illness is recently named as a mood disorder according to the ICD-10 or DSM-III R diagnostic criteria. It consists of two opposite states, manic state and depressive state. Typical manic symptoms include a pathologic delightful mood, flight of ideas, heightened level of activity and sexual interest. Grandiosity, rapid and pressured speech, increased energy and decreased need for sleep are also frequently seen. On the other hand, depressive symptoms are characterized by prolonged depressive mood, inhibition of thought, lowered level of activity, depressive ideas or delusions and various somatic dysfunctions such as loss of appetite and sleep disturbance. Mood disorders are often seen in association with organic brain diseases, collagen diseases such as SLE, some endocrinological diseases and medication. Diagnosis of manic or depressive states is usually carried out by careful psychiatric interviews. No specific somatic symptoms or signs have been identified for manic-depressive illness. Many rating scales, for instance Zung's SDS or HDSR, have been utilized as diagnostic aids. Rating scales and the symptomatology and diagnosis of manic-depressive illness are described in general.
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PMID:[Symptomatology and diagnosis of manic-depressive illness]. 800 80