Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024141 (systemic lupus erythematosus)
44,322 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Crusted scabies (Norwegian scabies) is uncommon in clinical practice and may present as papulosquamous dermatosis. A case of crusted scabies in systemic lupus erythematosus (SLE) is described. The skin lesions simulated those of subacute cutaneous lupus erythematosus of the papulosquamous type, and became the source of epidemic scabies in the hospital. The colonization with Staphylococcus aureus within crusted lesions may have contributed to the patient's sepsis. This case illustrates the pitfalls in recognition of crusted scabies and the importance of rapid diagnosis.
...
PMID:Crusted scabies in systematic lupus erythematosus: a case report. 813 60

Norwegian type scabies is a severe skin infestation which has been described in both immunosuppressed and immunocompetent people. We report a case of Systemic Lupus Erythematosus (SLE) presenting as Norwegian scabies in a malnourished patient who had exceedingly high levels of serum IgE and low IgG 1. The CD(4) count was normal but the ratio CD(4)/CD(8) was decreased as a result of an increased CD(8) count. The extensive skin disease which led to the diagnosis of Systemic Lupus Erythematosus was unresponsive to treatment until the SLE was properly controlled by therapy. The possible relationship between high IgE and low IgG1 levels and Norwegian scabies is discussed in the context of systemic lupus erythematosus.
...
PMID:Scabies Norwegian Associated With High IgE and Low IgG1 Levels Presenting as Systemic Lupus Erythematosus. 1110 17