Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024141 (systemic lupus erythematosus)
 44,322 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cranial neuropathy, and particularly facial palsy, is a rare occurrence in patients with systemic lupus erythematosus (SLE). We describe a 16-year-old female who developed bilateral facial palsy concomitant with cutaneous bullous eruption, alopecia, mucosal ulcers, arthritis, lymphadenopathy, parotid enlargement, and proteinuria. The lack of positive antinuclear antibody (ANA) at presentation obscured the diagnosis. Her followup course clarified the diagnosis of SLE. We believe this is the first report of ANA negative SLE presenting as bilateral facial palsy.
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PMID:Antinuclear antibody negative systemic lupus erythematosus presenting as bilateral facial paralysis. 955 89

Facial nerve palsy is the most common cause of mononeuropathy in the humans, Bell's palsy being the commonest cause of that. Cranial neuropathy, particularly facial is a rare event in systemic lupus erythematosus (SLE). The authors hereby report on a 20-year-old female patient who had recurrent lower motor neuron type facial palsy and on subsequent workup she was diagnosed as a case of SLE. She was put on oral prednisolone to which she showed gradual response. The authors believe that this is the first case report of SLE presenting as recurrent facial palsy.
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PMID:Recurrent lower motor neuron type facial palsy: an unusual manifestation of SLE. 2271 27