Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023890 (cirrhosis)
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Human Gene/Protein
TMEM82 9.6
AHNAK-related protein 9.6
C1orf61 protein 9.6
rheumatoid factor RF-IP20 9.6
chromosome 1 open reading frame 61 9.6
FLJ13081 9.6
syntaxin binding protein 5-like 9.6
eukaryotic translation initiation factor 3, subunit I 9.6
SCAN domain containing 3 9.6
BRUNOL5 9.6
RecA homolog, E. coli 9.6
degenerative spermatocyte homolog 1 9.6
DHX9 protein 8.6
Hexokinase III 8.6
SERPINA11 8.6
FIBCD1 protein 8.6
HBEX2 8.6
LOC55908 8.6
Transmembrane 6 superfamily member 2 8.6
Delta-like 1 protein 8.6
XLKD1 8.6
DENN/MADD domain containing 2D 8.6
GXIIB 8.6
SAMD4B 8.6
ABCB4 protein 8.3
Zinc finger protein 267 8.2
CLIF 8.1
MBOAT7 8.0
ZNF282 8.0
STK25 protein 8.0
Angiogenic factor with G patch and FHA domains 1 8.0
PDE4a 8.0
SRRD 8.0
skeletal muscle and kidney enriched inositol phosphatase 8.0
KIAA1210 8.0
MAGEB3 8.0
TM6SF2 7.9
transmembrane 6 superfamily member 2 7.7
HBxAg 7.6
zinc finger protein 267 7.6
LPPR4 7.6
NCU-G1 7.6
LH-B 7.6
GTP-binding protein 1 7.6
Exportin 4 7.6
PHKG2 7.6
KAT4 7.6
scavenger receptor class A, member 5 7.6
F-box protein 31 7.6
FAM72D 7.6
Forkhead box F2 7.6
TALDO1 7.5
HSD17B13 7.4
PNPLA3 7.4
XPO4 7.4
TMC4 7.4
PHKB 7.4
GP73 7.3
C17orf32 7.2
Noxp20 7.2
human homolog of mouse double minute 2 7.2
Zinc finger protein A20 7.2
macrophage inflammatory protein 3 7.2
FN1 protein 7.2
Ras homolog gene family, member C 7.2
MCART1 7.2
CCDC115 7.2
MAP3K15 7.2
Jun activation domain binding protein 7.2
HCC 7.1
Hemochromatosis 7.1
PFIC 7.1
hemochromatosis 7.0
nucleosome assembly protein 1-like 1 7.0
SART1259 7.0
ADAM8 protein 7.0
FETUB 7.0
THBS3 7.0
TSPAN6 7.0
actin, alpha 2, smooth muscle, aorta 7.0
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Disease
Renal cirrhosis 9.6
Protein intolerance 9.6
Cholemic nephrosis 9.6
Tuberculous ascites 9.6
Acquired porphyria 9.6
cirrhosis 9.6
Disorder of vitamin D 9.6
infection; local 9.6
Duodenopathy 9.6
Fleisher ring 9.6
HC/HCC 9.6
adult primary liver cancer 9.6
Disorder of immune function 9.6
Lead neuropathy 9.6
Primary cholangitis 9.6
Thrombocytopenia due to hypersplenism 9.6
Hepatic glomerulosclerosis 9.6
rectosigmoid growth 9.6
Subfulminant hepatic failure 9.6
Granulomatous liver disease 9.6
Cirrhosis 9.6
Cryptogenic cirrhosis 9.4
Advanced cirrhosis 9.3
Decompensated cirrhosis 9.2
Macronodular cirrhosis 9.2
Micronodular cirrhosis 9.1
Other liver diseases 9.0
Spontaneous bacterial peritonitis 8.9
Chronic liver disease and cirrhosis 8.7
hepatorenal syndrome 8.6
Alcohol-induced chronic pancreatitis 8.6
Subacute myocarditis 8.6
Subacute hepatic failure 8.6
Carcinomatosis peritonei 8.6
Infected ascites 8.6
Staphylococcus aureus cellulitis 8.6
Chronic active viral hepatitis 8.6
acquired hemochromatosis 8.6
FPLD1 8.6
Malignant neoplasm of trachea, bronchus and lung 8.6
Phosphoglucomutase deficiency 8.6
Retrosternal abscess 8.6
Early cirrhosis 8.6
Advanced chronic liver disease 8.6
Bantu siderosis 8.6
Acute cholestatic hepatitis 8.6
Acute peptic ulcer 8.6
stenosing cholangitis 8.6
Cardiac cirrhosis 8.6
Hepatobiliary neoplasms 8.6
Rhinocerebral phycomycosis 8.6
Drug-induced aplastic anemia 8.6
Chronic viral hepatitis 8.5
chronic persistent hepatitis 8.5
Cruveilhier-Baumgarten syndrome 8.5
Portal hypertensive gastropathy 8.4
Other hepatitis 8.3
alcoholic cirrhosis 8.3
Secondary biliary cirrhosis 8.3
Hepatic fibrosis and cirrhosis 8.3
cholestatic cirrhosis 8.2
Alcoholic liver disease 8.2
Kupffer cell sarcoma 8.2
Acquired dysfibrinogenemia 8.2
Bleeding esophageal varices 8.2
Alcoholic liver damage 8.2
alcoholic hepatitis 8.2
Hepatopulmonary syndrome 8.2
Chronic hepatitis C 8.2
Chronic hepatitis B 8.2
liver scarring 8.2
acute alcoholic hepatitis 8.2
portal hypertension 8.2
bacterial peritonitis 8.1
Portopulmonary hypertension 8.1
Duodenal varices 8.1
chronic active hepatitis 8.1
Hepatic osteodystrophy 8.1
Nonalcoholic fatty liver 8.0
chronic liver disease 8.0
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Symptom
Exquisite pain 8.6
Right hypochondrial pain 8.6
Venous hum 8.6
Pericardial knock 8.6
liver pain 8.1
Palmar erythema 7.8
left carotid bruit 7.6
Edema of the lower limbs 7.6
Kayser-Fleischer ring 7.1
Hyposensitivity 6.8
Medusa's head 6.8
retrosternal discomfort 6.4
Upper abdominal pain 6.2
asterixis 6.0
Homan's sign 6.0
disturbed speech 5.6
hepatomegaly 5.5
Moderate pain 5.5
loss of feeling 5.4
Kussmaul's sign 5.2
clubbing 5.1
Platypnea 5.1
splenomegaly 5.0
koilonychia 4.9
swollen leg 4.8
right upper quadrant pain 4.6
left upper quadrant pain 4.5
tense 4.5
intestinal bleeding 4.5
breast hyperplasia 4.4
Tissue sensitivity 4.4
Orthostasis 4.4
Cardiovascular symptoms 4.2
pedal edema 4.1
lumbar back pain 4.1
hepatosplenomegaly 4.1
muscle cramps 4.1
abdominal fullness 4.0
Neurologic symptoms 4.0
leg edema 3.9
cardiovascular impairment 3.8
hypoproteinemia 3.8
infant diarrhea 3.8
Flu-like symptoms 3.8
Severe diarrhea 3.8
dark urine 3.7
General symptoms 3.7
Murphy's sign 3.6
Organ failure 3.6
intestinal angina 3.5
Skin symptoms 3.5
staggering gait 3.4
leg cramps 3.4
No toxic effect 3.2
prominent nose 3.2
Motor dysfunction 3.2
Pain at rest 3.2
oliguria 3.1
abdominal pain 3.1
hyperemesis gravidarum 3.0
Crawling 3.0
asthenia 3.0
emaciation 3.0
abnormal breathing 2.8
abdominal discomfort 2.8
ataxic gait 2.8
inanition 2.8
disturbed balance 2.7
generalized erythema 2.7
bigeminal 2.6
decreased appetite 2.5
consciousness disturbance 2.5
Signs and Symptoms 2.4
lassitude 2.4
generalized rash 2.4
dysarthria 2.4
Gastrointestinal symptoms 2.4
pleuritic chest pain 2.4
orthopnea 2.3
right lower quadrant pain 2.3
more...
Drug
PLV-2 9.6
Technetium Tc 99m sulfur colloid 9.6
Lauromacrogol 9.6
CINU 9.6
Livact 9.0
Entocort EC 8.6
Arclofenin 8.6
Lidofenin 8.6
Terlipressin 8.3
Terlipressin 8.3
IFEX 8.0
Aldioxa 8.0
Lixivaptan 7.9
Peretinoin 7.2
Syprine 7.2
Entecavir 7.1
Entecavir 7.1
Conivaptan 6.8
Diammonium glycyrrhizinate 6.8
Malotilate 6.8
Rifaximin 6.7
Tolvaptan 6.7
Duphalac 6.7
Clevudine 6.6
Disofenin 6.6
Adefovir dipivoxil 6.3
Infergen 6.2
Telbivudine 6.2
Pegasys 6.2
Menotropins 6.1
Bear bile 6.1
Torasemide 6.0
Muromonab-CD3 6.0
Glafenine 6.0
Mangafodipir trisodium 6.0
Paromomycin sulfate 6.0
Xipamide 5.9
Lipiodol 5.9
Bucolome 5.9
Lutropin alfa 5.9
Perhexiline maleate 5.9
Vapreotide 5.9
Hepatitis B immune globulin 5.9
Valoron 5.9
Bucrylate 5.8
Portal 5.8
Selenium sulfide 5.8
Camellia oil 5.8
Tegison 5.8
Candoxatrilat 5.8
E.A.C 5.7
Wellferon 5.7
Viramidine 5.6
Romet 5.6
Quinaprilat 5.5
Thymalfasin 5.5
Ethanolamine oleate 5.5
Phenobarbital sodium 5.4
Zonegran 5.4
Midodrine 5.4
Intron A 5.3
Intron A 5.3
Intron A 5.3
Ferrum 5.2
Sonazoid 5.2
Interferon alfa-2a 5.2
Tenofovir 5.1
Gamma globulin 5.1
Dyazide 5.0
Sorafenib 5.0
Ferumoxides 5.0
Levovist 5.0
Tenofovir disoproxil fumarate 5.0
Nexavar 4.8
Gliquidone 4.8
Aethoxysklerol 4.8
Muzolimine 4.8
Maltitol 4.7
PMEA 4.7
Molsidomine 4.7
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Enzyme
L-fucose dehydrogenase 7.0
BAST I 6.8
7alpha-dehydroxylase 6.4
type III procollagen 6.3
guanosine deaminase 6.2
pyridoxal oxidase 5.9
kallikrein 10 5.8
proprotein convertase 2 5.8
alanine aminotransferase 5.4
fumarylacetoacetate hydrolase 5.2
AST 5.2
acylcarnitine hydrolase 5.2
PdxH 4.9
amylo-1,6-glucosidase 4.8
PLP phosphatase 4.8
aspartate aminotransferase 4.8
galactosylhydroxylysyl glucosyltransferase 4.8
gamma-glutamyl transpeptidase 4.7
ADH3 4.7
TACE 4.7
phosphoethanolamine cytidylyltransferase 4.6
beta-D-fucosidase 4.6
BCKA 4.5
phosphatidylethanolamine N-methyltransferase 4.3
N-acetylglucosamine kinase 4.3
FucT 4.3
inosine triphosphatase 4.3
prolyl hydroxylase 4.3
alpha-L-fucosidase 4.2
CYP7B1 4.2
branching enzyme 4.2
uroporphyrinogen decarboxylase 4.1
EC 2.4.99.1 4.1
alpha-L-fucosidase 4.1
matrix metalloproteinase 14 4.1
CYP8B1 4.1
prolinase 4.0
transpeptidase 4.0
EC 2.4.1.11 4.0
phospholipid methyltransferase 3.9
PMT 3.9
chymotrypsin C 3.9
ceruloplasmin 3.9
site-1 protease 3.8
sarcosine dehydrogenase 3.8
alpha-L-fucosidase 3.7
serum carnosinase 3.7
transaldolase 3.7
phosphoinositide 5-phosphatase 3.7
PPH 3.6
N-acetylglucosaminyltransferase II 3.6
isoamylase 3.6
carbamoylphosphate synthetase 3.6
creatinase 3.6
nardilysin 3.6
DHAD 3.6
GSase 3.6
branched-chain alpha-keto acid dehydrogenase 3.5
ADH 3.5
methionine adenosyltransferase 3.5
cholinesterase 3.4
endo-alpha-N-acetylgalactosaminidase 3.4
PME 3.4
glutamic dehydrogenase 3.3
threonine aldolase 3.3
4-hydroxyphenylpyruvate dioxygenase 3.3
HPI 3.3
guanase 3.3
betaine-homocysteine methyltransferase 3.2
dihydroxyacetone phosphate acyltransferase 3.2
lecithin:retinol acyltransferase 3.2
retinyl ester hydrolase 3.2
renin 3.0
thromboxane synthase 3.0
retinol acyltransferase 3.0
alkaline phosphatase 3.0
N-acetylglucosaminyltransferase III 3.0
AGT 3.0
coagulation factor VIIa 2.9
alcohol dehydrogenase 2.9
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Compound
C20H21NO5 9.6
C20H21NO5 9.6
C20H21NO5 9.6
C20H21NO5 9.6
Allyl isovalerate 9.6
C20H21NO5 9.6
C20H21NO5 9.6
C16H20O5 8.6
4-Chloro-4'-aminodiphenyl ether 8.6
Meladrazine 8.6
C19H18O7 8.6
C21H20N2O2 8.6
C14H16N2O4S 8.6
N-acetyl-gamma-aminobutyrate 8.6
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
Papaverinol 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
N1,N12-Diacetylspermine 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
C9H9NO 8.0
Columbamine 8.0
Remestyp 8.0
C9H9NO 8.0
Nicon 7.6
C16H14O3 7.6
C9H9NO 7.6
C9H9NO 7.6
C9H9NO 7.6
furostan-3,26-diol 7.6
C9H9NO 7.6
C9H9NO 7.6
3-(4-hydroxyphenyl)propanenitrile 7.2
C9H9NO 7.2
PGF3alpha 7.2
TIPPS 7.0
ARA-AMP 7.0
C10H15NO 7.0
C15H10O2 7.0
Wuweizisu C 7.0
3-phenylacrylamide 6.8
Thiocolchicine 6.8
2,3,4-trihydroxybutanoic acid 6.8
Ursodeoxycholic acid 6.7
CPH 6.7
Primobolan 6.6
C10H16O4 6.6
Carfecillin 6.6
C11H13NO3 6.4
Heliotrine 6.4
CCl4 6.2
5,6-dimethoxy-1-indanone 6.2
Lasiocarpine 6.2
C 80 6.2
Rhodanine 6.2
Interferon alfa-2a 6.2
Sulfobromophthalein 6.1
BW 301U 6.1
p-Toluidine 6.1
NMHE 6.0
5-Methoxyindole 6.0
C20H24N2O4 6.0
C9H11NO2 6.0
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