Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 2695
interferon 1958
insulin 1400
albumin 1152
collagen 904
Mol 865
surface antigen 854
alpha-fetoprotein 774
alanine aminotransferase 746
prothrombin 649
serum albumin 565
HCC 552
gut 507
alkaline phosphatase 503
aspartate aminotransferase 488
cytokine 463
IFN 461
hemochromatosis 411
She 387
renin 387
vasopressin 360
AST 294
AFP 290
MRI 287
interferon-alpha 247
ferritin 241
ras 231
endoplasmic reticulum 227
glucagon 221
hemoglobin 210
tumor necrosis factor 209
IgA 201
chronic renal failure 200
CD4 198
TNF 192
p53 191
fibrinogen 191
glycoprotein 186
transferrin 175
microsomal 174
HFE 165
IL-6 161
interferon alpha 155
HLA 150
protease inhibitor 149
Pol 148
somatostatin 145
Alpha-fetoprotein 144
SMA 141
PEG 141
thrombin 138
alpha 1-antitrypsin 135
lipopolysaccharide 127
smooth muscle actin 118
lymphoid 116
C-reactive protein 116
hepatocyte growth factor 114
alpha-1-antitrypsin 112
FIB 112
CD8 112
cytochrome P450 111
hereditary hemochromatosis 109
interleukin-6 108
core protein 103
ATP 101
polypeptide 101
fibronectin 100
reserved 100
angiotensin II 98
Wilson disease 96
nitric oxide synthase 94
GSH 92
growth hormone 91
ceruloplasmin 90
IL-10 90
alpha-smooth muscle actin 88
vascular endothelial growth factor 88
superoxide dismutase 88
GPT 85
antithrombin III 84
atrial natriuretic peptide 84
lectin 82
arginine vasopressin 80
Albumin 80
TNM 79
endothelin-1 79
leptin 77
GGT 75
lactate dehydrogenase 74
Cytokine 74
gamma-glutamyl transpeptidase 73
HDL 73
adiponectin 72
proliferating cell nuclear antigen 72
protein C 71
catalase 70
TNF-alpha 69
chemokine 69
carcinoembryonic antigen 68
plasminogen 68
PNPLA3 67
collagenase 65
alcohol dehydrogenase 64
atrial natriuretic factor 64
thromboplastin 63
caspase-3 63
inducible nitric oxide synthase 61
TLR4 61
type I collagen 60
factor VIII 60
peroxidase 60
ATPase 59
PBC 59
glutathione peroxidase 59
tumor necrosis factor alpha 58
kit 58
IL28B 58
serum protein 58
thrombopoietin 57
antithrombin 56
mTOR 56
catenin 56
matrix metalloproteinase 55
prolactin 54
transforming growth factor-beta 54
cytochrome 53
gamma-glutamyltransferase 53
human leukocyte antigen 53
cytokeratin 19 52
PLA 52
farnesoid X receptor 51
Fas 51
von Willebrand factor 51
TGF-beta 51
CYP2E1 50
platelet-derived growth factor 50
IL-8 50
cytochrome P-450 50
non-Hodgkin's lymphoma 50
Pseudomonas 49
peroxisome proliferator-activated receptor 49
JNK 48
proton pump 48
AMP 48
AKT 48
GTG 47
amylase 47
CD34 47
NMR 46
p38 46
tyrosine kinase 46
calcineurin 46
cage 45
STAT3 45
cyclooxygenase 45
haptoglobin 45
cytokeratin 45
ALP 45
erythropoietin 45
xenobiotic 45
more...
Disease
cirrhosis 42195
hepatocellular carcinoma 11620
liver disease 7868
chronic hepatitis 5719
hepatitis C 5104
hepatitis B 4510
cancer 3969
hepatitis 3766
portal hypertension 3469
tumor 3028
chronic liver disease 3022
liver fibrosis 2386
liver cancer 2024
fatty liver 1889
diabetes 1834
viral hepatitis 1466
liver cancer 1446
chronic active hepatitis 1388
hepatic encephalopathy 1374
obesity 1266
esophageal varices 1232
Nonalcoholic fatty liver 1193
virus infection 1176
varices 1148
Cirrhosis 1117
Hepatocellular carcinoma 1097
cholestasis 1052
alcoholic cirrhosis 1025
carcinoma 890
acute hepatitis 849
primary biliary cirrhosis 807
encephalopathy 757
HIV 725
metabolic syndrome 723
hypertension 692
alcoholism 690
renal failure 630
alcoholic fatty liver 611
cholangitis 610
sepsis 595
hemochromatosis 578
alcoholic hepatitis 570
HCC 552
hepatorenal syndrome 536
alcohol abuse 522
sepsis 522
chronic persistent hepatitis 517
heart failure 501
carcinogenesis 496
bacterial peritonitis 489
type 2 diabetes 478
metastases 445
primary sclerosing cholangitis 436
immunodeficiency 427
infectious diseases 422
malnutrition 419
iron overload 406
thrombocytopenia 402
anemia 369
gallstones 364
Chronic hepatitis C 345
Chronic hepatitis B 343
renal disease 341
congestive heart failure 338
Wilson's disease 334
biliary atresia 317
cardiovascular disease 317
pneumonia 295
viremia 288
Infection 288
pancreatitis 276
peritonitis 272
cardiomyopathy 270
tuberculosis 255
AIDS 247
chronic renal failure 237
coagulopathy 234
ischemia 219
hypersplenism 215
pruritus 213
NS3 212
Budd-Chiari syndrome 211
emphysema 207
bacteremia 194
nephrotic syndrome 193
cystic fibrosis 192
hepatitis A 191
tumorigenesis 190
stroke 190
lymphoma 189
Alcoholic liver disease 186
inflammatory bowel disease 184
chronic pancreatitis 181
dysplasia 181
depression 179
hereditary hemochromatosis 179
hepatitis D 179
hyperlipidemia 176
heart disease 175
obstructive jaundice 173
schistosomiasis 167
rheumatoid arthritis 165
coma 164
renal insufficiency 163
pulmonary hypertension 157
Portal vein thrombosis 157
dyslipidemia 156
Chronic infection 155
disseminated intravascular coagulation 155
atherosclerosis 153
osteoporosis 153
glomerulonephritis 152
hydrothorax 151
lung cancer 151
West 151
chronic disease 149
biliary obstruction 148
renal impairment 148
bacterial infection 143
myocardial infarction 142
glucose intolerance 141
ulcerative colitis 138
chronic obstructive pulmonary disease 137
tumor progression 135
autoimmune disease 135
gastric cancer 134
peptic ulcer 133
hyperbilirubinemia 132
arterial embolization 131
Best 130
Spontaneous bacterial peritonitis 129
SEM 128
systemic lupus erythematosus 128
hepatitis E 126
arthritis 125
Autoimmune hepatitis 124
adenocarcinoma 123
liver metastases 122
hyperinsulinemia 120
leukemia 115
cognitive impairment 114
hyperglycemia 114
tumor growth 113
cryoglobulinemia 113
Crohn's disease 112
suicide 112
myocardial ischemia 111
acute renal failure 111
adenoma 111
vasculitis 108
breast cancer 106
hypothyroidism 104
celiac disease 98
B virus infection 98
cytomegalovirus 98
hypogonadism 97
colorectal cancer 96
hepatic coma 96
hemangioma 95
lung disease 94
more...
Symptom
splenomegaly 407
abdominal pain 352
hepatomegaly 349
pain 267
fatigue 263
diarrhea 185
anesthesia 166
dyspnea 145
overweight 129
weakness 117
vomiting 105
hepatosplenomegaly 99
nausea 94
anorexia 77
headache 75
tense 65
seizures 57
cough 52
tremor 47
respiratory distress 47
arthralgia 46
exhaustion 45
clubbing 42
starvation 40
collapse 40
Ill 36
erythema 35
ataxia 34
shortness of breath 33
discomfort 33
discomfort 33
sleepiness 31
cachexia 29
asthenia 28
constipation 28
angina 27
dysarthria 26
chills 25
chest pain 25
lethargy 25
cyanosis 24
intestinal bleeding 24
dystonia 23
right upper quadrant pain 22
oliguria 21
hypoproteinemia 21
myalgia 21
exertional dyspnea 20
hemoptysis 20
hypothermia 20
muscle cramps 20
analgesia 20
epigastric pain 19
polyuria 19
asterixis 18
back pain 18
insomnia 17
paraparesis 16
abdominal discomfort 16
hypotonia 15
regurgitation 14
acute abdomen 14
Kayser-Fleischer ring 13
leg edema 13
dizziness 13
stigma 13
acute abdominal pain 12
flushing 12
emaciation 11
nausea and vomiting 11
fever of unknown origin 11
agitation 10
colic 10
bone pain 9
acidity 9
abdominal fullness 9
decreased appetite 9
functional recovery 9
low back pain 9
HSA 9
spasticity 9
syncope 8
paresthesia 8
flank pain 7
polydipsia 7
thinning 6
hyperemesis gravidarum 6
consciousness disturbance 6
ophthalmoplegia 6
Wind 6
hypocapnia 6
pallor 6
Platypnea 5
leg pain 5
apathy 5
ataxic gait 5
tonic-clonic seizure 5
pedal edema 5
paresis 5
dark urine 5
cerebellar ataxia 5
left upper quadrant pain 4
retrosternal discomfort 4
spasm 4
hemiplegia 4
Neurologic symptoms 4
hypercapnia 4
pleuritic chest pain 4
Gastrointestinal symptoms 4
night sweats 4
numbness 4
hyperoxia 3
dry skin 3
liver pain 3
heartburn 3
ENT 3
neck pain 3
wheezing 3
cancer pain 3
hunger 3
Decreased activity 3
Welt 3
dysuria 3
Stiffness 3
orthopnea 3
Palmar erythema 3
myoclonus 3
microbial colonization 3
neuralgia 3
neurological disability 3
chronic constipation 3
limb pain 3
bradykinesia 3
loss of balance 2
halitosis 2
rales 2
sore throat 2
renal colic 2
eye pain 2
lumbar back pain 2
shoulder pain 2
Upper abdominal pain 2
memory loss 2
infant diarrhea 2
tachypnea 2
cardiovascular impairment 2
tinnitus 2
vertigo 2
breath holding 2
prostration 2
blurred vision 2
hoarseness 2
lassitude 2
bitter taste 2
abnormal breathing 2
right lower quadrant pain 2
inanition 2
leg cramps 2
intention tremor 2
incoordination 2
more...
Drug
Portal 307
Cardiovasc 141
vitamin E 124
Dermatol 100
Albumin 92
Ethanol 89
ROC 89
caffeine 70
Sorafenib 65
Lipiodol 64
Biopolymers 62
Monit 61
lysine 48
Dial 46
Terlipressin 45
Terlipressin 45
Nephron 42
Entecavir 41
Entecavir 41
IL-2 38
nitroglycerin 36
ROS 35
IFN-gamma 34
ampicillin 33
Serum albumin 33
Tolvaptan 29
Rifaximin 28
EE2 26
PMEA 25
PMPA 25
Nephron 25
CSF 25
ENT 23
NADH 23
ascorbate 23
Vitamin E 22
Adriamycin 20
Glucagon 20
MAP 20
Vitamin A 19
Tenofovir 19
Paraffin 19
ABC 18
Angiotensin II 16
Bifidobacterium 16
Glutathione 15
Cimetidine 15
Prednisolone 15
Cimetidine 15
NH3 15
Gel 14
EPI 14
Gelfoam 14
Indocyanine green 13
Adefovir dipivoxil 13
Alanine 13
Tacrolimus 12
Dakar 12
Levovist 11
Indomethacin 11
Prednisone 10
PTH 10
Vitamin K 10
CCL 10
IFN-beta 10
Pegasys 9
Retinoic acid 9
GEO 9
Torasemide 9
Growth hormone 9
Growth hormone 8
Fructose 8
ETA 8
Telbivudine 8
DDAVP 8
Bosentan 8
Sonazoid 8
ADM 8
Bosentan 8
Tenofovir disoproxil fumarate 7
Intron A 7
Heme 7
Intron A 7
DDAVP 7
CTX 7
Simvastatin 7
Galactose 7
Antithrombin III 7
Gastro 7
Theophylline 7
PTC 6
ALA 6
Alliance 6
THA 6
citric acid 6
Bayer 6
NAG 6
MRC 6
Rituximab 6
Intron A 6
pyridoxal phosphate 6
Aprotinin 6
G-CSF 6
Conivaptan 6
Amoxicillin 6
ATV 5
p75 5
CaCl2 5
Activin 5
Lixivaptan 5
lactose 5
CaCl2 5
Midodrine 5
Leaf 5
EPA 5
Fluorescein 5
Diphenhydramine 5
Molsidomine 5
Asn 5
Estrogens 5
CAM 5
Ezetimibe 5
CaCl2 5
Glycerol 5
Captopril 5
FCV 5
uPA 5
Nadolol 5
AGG 5
Secretin 4
Amiloride 4
Nexavar 4
CTA 4
Spectrum 4
AZT 4
Sandostatin 4
Orlistat 4
Sandostatin 4
Vitamin B12 4
Malotilate 4
Doxycycline 4
HCG 4
Neoral 4
Liraglutide 4
IPM 4
CPR 4
Bumetanide 4
BH4 4
Omeprazole 4
Kenyan 4
Fraction 4
Perindopril 4
Clevudine 3
Inderal 3
Methylprednisolone 3
AIC 3
Propofol 3
Ulinastatin 3
CTC 3
Cyanoacrylate 3
more...
Enzyme
alanine aminotransferase 1477
aspartate aminotransferase 799
alkaline phosphatase 503
renin 387
gamma-glutamyl transpeptidase 317
AST 294
cholinesterase 178
acetylcholinesterase 155
mitogen-activated protein kinase 146
thrombin 130
reverse transcriptase 123
ERK 113
superoxide dismutase 110
collagenase 102
APC 100
ceruloplasmin 98
alcohol dehydrogenase 94
lactate dehydrogenase 84
catalase 83
peroxidase 83
type III procollagen 73
thromboplastin 72
protein kinase 68
ATPase 65
glutathione peroxidase 62
glutathione S-transferase 61
ACE 57
trypsin 57
focal adhesion kinase 56
NO synthase 54
calcineurin 52
transcriptase 52
caspase-3 51
RNA polymerase 47
DNA polymerase 47
prolyl hydroxylase 46
luciferase 44
tissue plasminogen activator 43
lipase 42
aldehyde dehydrogenase 42
phosphodiesterase 40
proteasome 37
NOS 37
plasmin 35
aldehyde dehydrogenase 33
ADH 33
AMP-activated protein kinase 32
transpeptidase 31
CYP3A4 31
glucose-6-phosphatase 31
aldehyde dehydrogenase 30
aldehyde dehydrogenase 30
urokinase-type plasminogen activator 30
aldehyde dehydrogenase 30
TACE 27
acid phosphatase 27
kallikrein 27
ACS 27
glutamate dehydrogenase 26
glutamate dehydrogenase 26
glutamate dehydrogenase 26
protein kinase C 25
phosphorylase 25
neuraminidase 24
CD10 24
guanylate cyclase 23
urease 22
elastase 22
adenosine deaminase 22
glutamine synthetase 22
urease 22
neutrophil elastase 22
adenosine deaminase 22
NADPH oxidase 21
monoamine oxidase 19
heme oxygenase 19
NADPH oxidase 19
beta-glucuronidase 18
creatine kinase 18
demethylase 17
RNase 17
pyruvate kinase 17
lysozyme 16
RNase 16
branching enzyme 15
pyruvate dehydrogenase 15
phospholipase A2 15
PARP 15
hexosaminidase 15
AMPK 14
MEK 14
arginase 14
pepsin 14
AMPK 14
fumarylacetoacetate hydrolase 14
glutathione reductase 13
ornithine transcarbamylase 13
alpha-L-fucosidase 13
alpha-L-fucosidase 12
MAP 12
alpha-L-fucosidase 12
beta-lactamase 12
MMP 12
cytochrome oxidase 12
P-glycoprotein 12
lecithin:cholesterol acyltransferase 12
xanthine oxidase 12
isoamylase 12
granzyme B 12
caspase-1 11
DNA methyltransferase 11
uroporphyrinogen decarboxylase 11
caspase-8 11
thymidine kinase 11
IKK 11
PRA 10
lysyl oxidase 10
UDP-glucuronosyltransferase 10
adenylate cyclase 10
glutaminase 10
methionine adenosyltransferase 10
PDE 10
transglutaminase 10
glucose-6-phosphate dehydrogenase 10
beta-galactosidase 10
ADH3 9
endonuclease 9
leucine aminopeptidase 9
cholesterol acyltransferase 9
cathepsin D 9
methylenetetrahydrofolate reductase 9
11beta-hydroxysteroid dehydrogenase 9
MMP-3 9
chymotrypsin 9
matrix metalloproteinase 2 9
phosphorylase kinase 9
cdc2 9
methylenetetrahydrofolate reductase 9
glyceraldehyde-3-phosphate dehydrogenase 9
succinate dehydrogenase 9
CPT 8
CPR 8
glyceraldehyde-3-phosphate dehydrogenase 8
lipoxygenase 8
ferrochelatase 8
hexokinase 8
PMT 8
matrix metalloproteinase 9 8
MIP 8
AGT 8
ALDH 7
pullulanase 7
GSK 7
DNase 7
phosphoinositide 3-kinase 7
paraoxonase 7
caspase-9 7
sulfatase 7
ribonuclease 7
ribonuclease 7
more...
Compound
Clin 4572
Dec 2807
DNA 1886
ethanol 1195
sodium 1083
water 886
glucose 804
iron 788
oxygen 606
ammonia 538
creatinine 520
CCl4 489
copper 373
nitric oxide 355
aldosterone 342
calcium 279
urea 275
methionine 261
zinc 238
nitrogen 221
His 196
TNF 192
Insulin 192
salt 191
potassium 186
tyrosine 184
arginine 180
galactose 179
PEG 177
leucine 163
PEG 146
alanine 144
phosphate 138
aldehyde 130
3TC 130
acetate 128
glutamine 124
hyaluronic acid 119
acetaldehyde 108
Phe 108
sulfate 108
Ile 104
GSH 104
GSH 104
ATP 101
CO2 99
noradrenaline 98
NH2 97
Cardiol 96
vitamin D 95
alcohol dehydrogenase 94
valine 91
isoleucine 90
tryptophan 89
isoleucine 86
serine 86
tryptophan 86
tryptophan 86
tryptophan 86
Ursodeoxycholic acid 85
GPT 85
manganese 79
TNM 79
glutamate 78
Ribavirin 78
hydrogen 77
ornithine 73
ornithine 73
ornithine 73
ornithine 73
ornithine 73
cysteine 73
Pac 72
caffeine 71
proline 71
adenosylmethionine 70
cGMP 65
selenium 63
ammonium 61
lysine 61
Propranolol 60
Propranolol 58
TAA 57
Optimal 55
aflatoxin B1 54
Sodium 54
nitrate 53
threonine 52
glycerol 51
aldehyde 50
Collagen 50
Vasopressin 50
TSH 49
prostacyclin 48
retinol 48
AMP 48
phosphorus 47
Dial 46
ALP 45
DTPA 42
PAS 42
TOF 40
iodine 39
DIC 38
formaldehyde 38
6-12 37
GABA 36
PGE2 36
silver 35
Asp 35
Silymarin 35
GABA 35
CPH 35
cAMP 33
N-acetylcysteine 33
vinyl 33
TRH 32
Parenteral 32
Methotrexate 31
Nodular 31
ASA 31
L-carnitine 30
ACS 29
SDS 29
acetic acid 28
FK506 28
homocysteine 28
prostaglandin E1 27
GMP 27
TACE 27
Adriamycin 26
ADP 26
Bilirubin 26
retinoic acid 26
Angiotensin II 26
Octreotide 26
ACS 26
Vitamin E 25
betaine 25
Abbott 25
Spironolactone 25
Colchicine 24
Antipyrine 24
Diabetol 24
glutamic acid 24
nicotinamide 24
Metformin 24
Metformin 24
AAT 23
NADH 23
Salix 23
Thyroid 23
Gly 23
ANA 22
ANA 22
MDA 22
H2S 21
Vitamin D 21
5-FU 21
PMEA 21
more...