Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors have observed cancer of the liver without cirrhosis, in a woman aged 32. The disease manifested itself immediately after childbirth and provoked death 3 months after the delivery. Before her pregnancy, the patient had been taking Infecundin for 7 years. The pregnancy went to term without any difficulty. The symptoms appeared after the delivery: abdominal pain, more and more frequent spasms in the right side, increasing progressively in intensity. The body temperature rose to 38 degrees Celsius. The patient lost some weight and became weaker and weaker every day. A malignant tumor of the liver was discovered. A laparotomy was performed: both lobes of the liver were of considerable size with swollen, grey-white growths the size of cherries. The patient died 3 months after the appearance of the 1st symptoms. A study of the literature published on this subject suggests the possibility of a connection between the malignant tumors in the liver and the prolonged use of oral contraceptives combined with the hormonal changes occuring during pregnancy.
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PMID:[Primary liver cancer following prolonged use of contraceptive drugs]. 18 70