Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The growing scepticism about the use of portocaval anastomosis operations to prevent renewed bleeding of esophageal varices has led to the testing of new methods. This report describes subcutaneous transposition of the resected spleen in normal experimental animals with the Vena porta constricted with Ameroid rings and liver cirrhosis induced by DMNA. The report also covers 9 patients operated on from 1972 to 1973 with subcutaneous transposition of the spleen. A 77-year-old woman died postoperatively, one patient died after 2 years 4 months, and one had slight bleeding. All the other patients are alive 2-4 years after the operation, with no signs of renewed bleeding. The advantage of subcutaneous transposition of the spleen is that it eliminates hypersplenism.
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PMID:[Subcutaneous transposition of the spleen: an experimental and clinical study (author's transl)]. 108 39

Budd-Chiari syndrome is an unusual form of portal hypertension caused by liver cirrhosis. Its mortality rate exceeds 50% within 2 years. Surgical therapy provides superior survival rates than conservative medical management. During 1984-1989, 58 cases of Budd-Chiari syndrome were treated at PUMC hospital. The age of these patients ranged from 16 to 62. There were 39 males and 19 females. Diagnosis was mostly made by simultaneous inferior and superior Vena Cavography and one case was diagnosed by liver biopsy. Intraluminal pressure measurement of IVC and diameter measurement of IVC by Doppler ultrasound method were used for diagnosis. Preoperative intraluminal mean pressure of IVC in 26 cases was 3.2 +/- 0.6 kPa and it decreased to 1.9 +/- 0.6 kPa postoperatively. (P less than 0.01) Digital membranotomy through right atrium was done in 34 cases, percutaneous balloon catheter dilatation in 7 cases and Meso-atrial shunt, inferior Vena Cava Atrial shunt were performed in 20 cases. Postoperative improvement was found in 85% of the patients during the follow-up period (from 2-60 months).
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PMID:[A report on 53 cases of Budd-Chiari syndrome]. 164 26

Transjugular intrahepatic shunts (TIPSs) are widely used in the management of portal hypertension complications including variceal bleeding, refractory ascites, and hepatic hydrothorax. Vena cava filters (VCFs) are an important therapeutic modality in the prevention of pulmonary emboli in patients suffering deep venous thrombosis and clinical contraindications for anticoagulation. Stent and filter misplacement or migration may occur, complicating liver transplantation (LT) surgery. We describe the intraoperative management of a patient with cirrhosis, who had a TIPS extending into the right atrium (RA) and a retrohepatic VCF. Stent and filter removals were deferred until the time of LT. Both procedures were performed successfully by complete cava and portal reconstruction. In conclusion, careful assessment and surgical management of patients with stent and filters permits successful LT.
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PMID:Liver transplantation with simultaneous removal of an intracardiac transjugular intrahepatic portosystemic shunt and a vena cava filter without the utilization of cardiopulmonary bypass. 1566 75