Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A morphological examination was carried out of 33 patients with cirrhosis of liver and 10 clinically healthy subjects. Chronic jejunitis, with the prevalence of its atrophic forms (in 59.1%) was established to develop in 86.4 per cent of the patients. The morphological characteristics of the changes observed (prevalence of dystrophic-destructive processes with marked lesions of the specialized structures, presence of hypore-generative and moderately manifested inflammatory reaction) allow that they be considered as endogenously conditioned forms of chronic jejunitis.
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PMID:[Changes in the small intestine mucosa in liver cirrhosis]. 46 36

Electron microscopy of epithelial cells of the mucous membrane of the duodenum and jejunum was performed in 20 patients with chronic hepatitis and liver cirrhosis to reveal changes in the structure of intracellular formations of epithelial cells of the cryptae and villi, of goblet and enterochromaffin cells. The most essential differences were found in mitochondria, granular cytoplasmic network, ribosomes, microvilli and glycocalix. There were no differences in the pattern of cellular changes in chronic hepatitis and liver cirrhosis. However, the degree of lesions increased in patients with liver cirrhosis. Morphologic changes seen in the mucous membrane of the small intestine (duodenitis and jejunitis) in chronic liver diseases present the morphologic substrate of digestion impaired by these diseases.
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PMID:[Ultrastructural changes in the epithelial cells of the small intestine mucosa in chronic liver diseases]. 736 72