Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Classification of vascular abnormalities of the gastrointestinal tract on the basis of anatomy and pathophysiology has recently been suggested. Angiodysplasia, an example of an arteriovenous lesion, may cause either acute or chronic bleeding. Diagnosis may be difficult. High-quality standard endoscopy, capsule endoscopy, and double-balloon enteroscopy are most efficacious. Therapy using argon plasma coagulation is currently preferred. Pharmacological therapy has been employed, but a final conclusion about its efficacy cannot yet be drawn. Dieulafoy lesion, an arterial type of vascular abnormality, is rare but serious. It can be responsible for severe haemorrhage. Mechanical endoscopic methods are the most efficacious. Gastric antral vascular ectasia (GAVE), a capillary lesion, can be safely biopsied; it coincides with several diseases (including liver cirrhosis), may cause chronic iron-deficiency anaemia, and is best treated by argon plasma coagulation. Haemangiomas, benign neoplastic lesions, usually occur as part of other specific syndromes; they are difficult to manage due to the multiplicity and size of the lesions.
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PMID:Vascular lesions of the gastrointestinal tract. 1834 86

Herbert Hoover, the archetypal self-made man, was the 31st president of the United States. His term in office was overwhelmed by the Great Depression and he was defeated by Franklin Delano Roosevelt in the 1932 November presidential election. His post-presidential years were spent writing and serving 4 subsequent presidents. Near the end of his life, he underwent a cholecystectomy for symptomatic gallstones and a colectomy for colon cancer. His health care was complicated by the development of cirrhosis and recurrent gastrointestinal bleeding. After his 90th birthday, he died in October 1964 from massive bleeding due to a Dieulafoy lesion of the gastric cardia. This manuscript will review the details of his health and the physicians who cared for Hoover during his final years.
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PMID:The Final Illness of Herbert Hoover. 3311 64