Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From history-taking and from analysis of plasma salicylate levels it is shown that a link exists between aspirin and gastrointestinal bleeding in 68% of cases. Salicylate levels alone indicate that aspirin has been taken in 22% of cases. Plasma salicylate measurement and endoscopy allow a better understanding of haemorrhagic lesions due to aspirin. Aspirin is responsible especially for haemorrhage from ulcers and acute gastritis or duodenitis. Aspirin is seen to be dangerous in a moderate number of susceptible individuals: those with peptic ulcer constitution or cirrhosis.
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PMID:Aspirin and gastrointestional bleeding. Interest of plasma salicylate determination. 31 93

An analysis of the 149 cases of haematemesis admitted to Coronation Hospital from January 1951, to September 1959, is presented. The commonest cause was found to be acute gastritis and gastric erosion. These cases were more common in males and usually followed on an alcoholic bout. These were in the main mild. Twenty-five cases associated with peptic ulceration were found, and the lesion occurred more commonly in males under the age of 40. Duodenal ulcer was commoner than gastric ulcer. The incidence of haematemesis with peptic ulceration appears to be on the increase, the cause of which is not known. Cirrhosis of the liver is a frequent cause of haematemesis and carries a high mortality.
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PMID:Upper gastrointestinal haemorrhage in the non-European. 1370 69