Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023890 (cirrhosis)
 42,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Serum IgG and IgD levels were determined in the following groups: professional blood donors, healthy smokers and patients with acute hepatitis, with acute salmonellosis, with hepatic cirrhosis, with cancer (prostate, lung and gastrointestinal tract) and with benign diseases of the same organs as the cancer patients. IgG was significantly increased in the groups of patients with hepatitis, hepatic cirrhosis and cancer. IgD values showed a wide dispersion in all the groups, which do not allow for comparisons among means. For that reason, linear regression analysis between IgG and IgD was done, the results being significant only in the two groups with infectious diseases (acute hepatitis and acute salmonellosis), which suggest that IgD could be involved in the immune response against their respective pathogenic agents.
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PMID:Serum IgG and IgD and levels in some infectious and noninfectious diseases. 65 27

Spontaneous bacterial peritonitis due to Salmonella is uncommon. We report three patients with ascites infected by Salmonella. All three patients had advanced chronic liver disease, typically cirrhosis with portal hypertension. Salmonella enteritidis grew in the ascite fluid culture of the three patients. There was no clinical or microbiological evidence of Salmonella infection other than in the ascitic fluid. One patient died before antibiotic treatment was started, but the other two were treated with different combinations of antimicrobial drugs. One of them died on the fourteenth day of hospitalization, and the other survived.
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PMID:Spontaneous bacterial peritonitis due to Salmonella enteritidis in cirrhotic ascites. 226 43

The case notes of patients with blood cultures positive for enterobacteriaceae were examined retrospectively over a 6-month period in Parirenyatwa Hospital, Harare, Zimbabwe. Speciation was possible for Salmonella typhi and shigellae only. Nontyphoidal salmonellae were serotyped. Salmonella or shigella bacteremia was identified in 51 patients. There were 14 isolates of S. typhi, 32 isolates of nontyphoidal salmonellae, and 5 isolates of shigellae species. The case notes of 38 patients could be identified for review, and of these HIV serology was available for 15 seropositive and 15 seronegative patients. The male to female ratio was approximately 3:1 for both groups and the mean age was 29.7 +or- 21. Nontyphoidal bacteremias as compared with typhoid fever were strongly associated with HIV seropositivity [p 0.01]. 3 out of 8 HIV-negative patients with nontyphoidal bacteremia had another underlying immunosuppressive disease [2 had myeloma and 1 patient had cirrhosis with complicating hepatoma]. 2 patients with nontyphoidal bacteremia whose HIV status was unknown also had another immunosuppressing disease [acute myeloid leukemia and idiopathic pancytopenia]. 13 out of 15 HIV-positive patients showed other signs of HIV infection [oral candida, herpes zoster, persistent generalized lymphadenopathy]. 3 out of 11 patients [27%] with typhoid died, while 11 out of 27 patients [40.7%] with nontyphi bacteremia died. Most strains of S. typhimurium were included in serogroup B, which accounted for 37% of nontyphoidal isolates. Earlier studies identified invasive salmonellosis in patients with other AIDS defining diseases. In Nairobi clinical features of HIV infection were found in 64% of bacteremic HIV-positive patients, but only 28% of patients fulfilled the CDC clinical case definition for AIDS. A more recent study from Nairobi demonstrated that S. typhimurium bacteremia is a common cause of intercurrent infection in HIV-positive tuberculous patients.
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PMID:Salmonella and shigella bacteraemia in Zimbabwe. 813 Nov 97

A 40-years-old woman with systemic lupus erythematosus and severe pulmonary nontyphoid salmonellosis (Salmonella Typhimurium), is reported. In addition the patient had incomplete septal cirrhosis. The authors pointed out a possible influence of Salmonella infection in the development of immune complex diseases.
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PMID:[Lupus erythematosus systemic and persistent pulmonary salmonellosis]. 901 88

Gradual decrease of salmonellosis is observed in Poland since 1988. In 1998, 26,739 cases of salmonellosis were noted, incidence rate = 69.2 per 100,000 population. Above 80% of cases were laboratory confirmed by isolation Salmonella strains (57 serotypes). Laboratory-based surveillance led to the identification 82 serotypes among examined persons; the most frequent serotype was Enteritidis: 90% of cases and 70% of Salmonella infected healthy persons. Serotypes: Typhimurium, Virchow, Hadar and Infantis caused 6% Salmonella infections. Nearly 53% of patients were hospitalized. Like in the previous years, the most affected age group were children under five (361/100,000). The extraintestinal Salmonella infections were observed in 64 patients for whom at least 1 nonfecal specimen was culture-positive for non-typhoidal Salmonella. Twenty eight patients had positive blood cultures (26--Enteritidis, 2--Typhimurium). The other positive specimens included subdural fluid (3), pleural fluid (3), joint fluid (2), urine (11) and pus (15). Half of the patients had immunocompromising conditions. Other diseases contributed to infection, especially in older patients, who had hematologic and nonhematologic malignancy, lupus erythematosus, diabetes, cirrhosis. There were 11 deaths (17%).
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PMID:[Salmonellosis in 1998]. 1107 49

A middle-aged man with decompensated cirrhosis and a dimorphic multisite skin rash is diagnosed with rare atypical herpes simplex infection, manifesting Sweet's syndrome (SS) in the absence of other described associations. SS, an acute febrile neutrophilic dermatosis, has three common forms-classical or idiopathic, malignancy associated and drug induced. Systemic autoimmune, connective tissue diseases and infections are also strong associations. The latter is commonly described in Gram-positive bacteria, salmonellosis and Yersinia Herpes infections are a rare cause of SS, reported only thrice in literature, one with concomitant lupus, the second with associated mycobacterial infection and third, in metastatic breast disease in contrast to our patient. Atypical rash, especially if dimorphic, warrants histopathological evaluation to confirm underlying disease.
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PMID:Strange case of dimorphic skin rash in a patient with cirrhosis: atypical herpes simplex and sweet's syndrome. 2905 8