Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023473 (chronic myeloid leukemia)
 18,916 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CML 0.172
ABL 0.085
BCR 0.061
bcr 0.033
BCR-ABL1 0.027
BCR/ABL 0.022
tyrosine kinase 0.016
breakpoint cluster region 0.011
p210 0.011
BCR-ABL fusion 0.010
bcr/abl 0.007
BCR/ABL fusion 0.007
ABL1 0.006
c-abl 0.005
ALL 0.004
AML 0.003
BCR-ABL fusion protein 0.003
P210 0.003
Tyrosine kinase 0.003
p190 0.001
interferon-alpha 0.001
c-ABL 0.001
CD34 0.001
BCR/ABL1 fusion 0.001
CEL 0.001
HLA 0.001
lymphoid 0.001
BCR/ABL protein 0.001
CLL 0.001
MDS 0.001
BCR/ABL fusion protein 0.001
CRKL 0.001
interferon alpha 0.000
interferon 0.000
erythroid 0.000
EVI1 0.000
AML1/MDS1 0.000
STAT5 0.000
JAK2 0.000
granulocyte 0.000
LAMA 0.000
granulocyte-macrophage 0.000
IFN 0.000
c-kit 0.000
KIT 0.000
CD33 0.000
AHI-1 0.000
non-Hodgkin's lymphoma 0.000
platelet-derived growth factor receptor 0.000
SRC 0.000
CMPD 0.000
G-CSF 0.000
FISH 0.000
SKI 0.000
protein tyrosine kinase 0.000
megakaryocyte 0.000
p230 0.000
organic cation transporter 1 0.000
FAB 0.000
NUP98 0.000
EVI-1 0.000
granulocyte colony-stimulating factor 0.000
SCT 0.000
IL-3 0.000
CD13 0.000
FLT3 0.000
TEL 0.000
NHL 0.000
MMR 0.000
MDS1 0.000
AML1 0.000
Ribosomal protein S27a 0.000
PDGFRB 0.000
HES 0.000
myelo 0.000
BCR protein 0.000
MLC 0.000
ABL1 protein 0.000
CD38 0.000
p13 0.000
more...
Disease
chronic myeloid leukemia 1.000
blast crisis 0.101
ABL 0.079
chronic phase CML 0.015
leukemia 0.012
acute myeloid leukemia 0.011
acute lymphoblastic leukemia 0.010
myeloproliferative disorders 0.008
Philadelphia chromosome positive 0.005
CML progression 0.004
acute leukemia 0.003
myelodysplastic syndrome 0.003
Leukemia 0.003
essential thrombocythemia 0.003
polycythemia vera 0.003
chronic myeloproliferative disorders 0.003
graft-versus-host disease 0.002
relapsed CML 0.002
primary myelofibrosis 0.002
chronic lymphocytic leukemia 0.002
myeloid leukemia 0.001
chronic lymphocytic leukemia 0.001
refractory CML 0.001
minimal residual disease 0.001
hematologic malignancies 0.001
myelofibrosis 0.001
thrombocytosis 0.001
accelerated phase CML 0.001
lymphoma 0.001
lymphoblastic leukemia 0.001
acute nonlymphocytic leukemia 0.001
leukemogenesis 0.001
cancer 0.001
Philadelphia chromosome positive chronic myelogenous leukemia 0.001
chronic leukemia 0.001
chronic myelomonocytic leukemia 0.001
chronic neutrophilic leukemia 0.001
Ph- CML 0.001
trisomy 8 0.001
chloroma 0.001
atypical chronic myeloid leukemia 0.001
MDS 0.001
aplastic anemia 0.000
multiple myeloma 0.000
acute promyelocytic leukemia 0.000
Ph-positive acute lymphoblastic leukemia 0.000
chronic eosinophilic leukemia 0.000
stromal tumors 0.000
non-Hodgkin's lymphoma 0.000
osteomyelofibrosis 0.000
acute undifferentiated leukemia 0.000
Acute graft-versus-host disease 0.000
hairy cell leukemia 0.000
B-ALL 0.000
osteomyelosclerosis 0.000
Hodgkin's disease 0.000
residual disease 0.000
tumor 0.000
T-cell acute lymphoblastic leukemia 0.000
chloroma 0.000
myelosuppression 0.000
juvenile myelomonocytic leukemia 0.000
Chronic GVHD 0.000
SCT 0.000
refractory anemia 0.000
NHL 0.000
acute monocytic leukemia 0.000
veno-occlusive disease 0.000
childhood chronic myelogenous leukemia 0.000
CP1 0.000
thrombocytopenia 0.000
adult ALL 0.000
CMD1 0.000
MLC 0.000
interstitial pneumonia 0.000
gastrointestinal stromal tumor 0.000
mastocytosis 0.000
FAB M4 0.000
Chloroma 0.000
monocytic leukemia 0.000
more...
Symptom
splenomegaly 0.000
hepatosplenomegaly 0.000
muscle cramps 0.000
No respiratory symptoms 0.000
chromosome marker 0.000
nausea and vomiting 0.000
nausea 0.000
periorbital edema 0.000
Roth spots 0.000
diarrhea 0.000
Mental status changes 0.000
bone pain 0.000
hepatomegaly 0.000
fatigue 0.000
non-productive cough 0.000
abdominal fullness 0.000
vomiting 0.000
pubic pain 0.000
Pain and tenderness 0.000
dyspnea 0.000
anorexia 0.000
swollen leg 0.000
Flu-like symptoms 0.000
nipple pain 0.000
nipple pain 0.000
myalgia 0.000
intestinal bleeding 0.000
headache 0.000
HSA 0.000
Lhermitte's sign 0.000
asthenia 0.000
abdominal pain 0.000
abdominal discomfort 0.000
localized edema 0.000
weakness 0.000
Ill 0.000
dry skin 0.000
erythema 0.000
arthralgia 0.000
facial droop 0.000
rigors 0.000
generalized rash 0.000
rales 0.000
Severe pain 0.000
paresthesia 0.000
cough 0.000
forgetfulness 0.000
chills 0.000
shortness of breath 0.000
arm weakness 0.000
night sweats 0.000
hip pain 0.000
pain 0.000
giddiness 0.000
giddiness 0.000
abnormal breathing 0.000
Gastrointestinal symptoms 0.000
Fluctuation 0.000
hypoproteinemia 0.000
No adverse effect 0.000
constipation 0.000
acute abdomen 0.000
cachexia 0.000
lethargy 0.000
consciousness disturbance 0.000
prostration 0.000
back pain 0.000
dysesthesia 0.000
otalgia 0.000
exhaustion 0.000
orthopnea 0.000
chest pain 0.000
tenesmus 0.000
productive cough 0.000
syncopal episodes 0.000
lightheadedness 0.000
blurred vision 0.000
decreased appetite 0.000
exertional dyspnea 0.000
respiratory distress 0.000
more...
Drug
Imatinib 0.028
Gleevec 0.018
Dasatinib 0.007
Bosutinib 0.002
MDS 0.001
G-CSF 0.000
lysine 0.000
TEL 0.000
Dacogen 0.000
KCL 0.000
Vindesine 0.000
Vindesine 0.000
Troxacitabine 0.000
Starasid 0.000
CSF 0.000
Anagrelide 0.000
Tiazofurine 0.000
TRM 0.000
Intron A 0.000
Intron A 0.000
Campath 0.000
Campath 0.000
Intron A 0.000
Roferon A 0.000
anti-CD33 0.000
Arsenic trioxide 0.000
Sobuzoxane 0.000
Ranimustine 0.000
ARA-C 0.000
Genasense 0.000
Interferon alfa-2a 0.000
Tipifarnib 0.000
Azacytidine 0.000
Fludarabine 0.000
BZQ 0.000
Cianidanol 0.000
Tetradecane 0.000
Roquinimex 0.000
Idarubicin 0.000
Radicicol 0.000
Piriprost 0.000
Hoelen 0.000
IFN-gamma 0.000
Oncophage 0.000
IL-2 0.000
Lenograstim 0.000
Forodesine 0.000
Tykerb 0.000
Hypaque 0.000
Nexavar 0.000
Herceptin 0.000
ADM 0.000
Hypaque 0.000
G418 0.000
VCR 0.000
Leaf 0.000
ROS 0.000
ADR 0.000
Antithymocyte globulin 0.000
Acadesine 0.000
Nelarabine 0.000
Clofarabine 0.000
Thioguanine 0.000
Bortezomib 0.000
Proleukin 0.000
Sunitinib malate 0.000
Etoposide 0.000
Gefitinib 0.000
CTX 0.000
AraC 0.000
Orphan 0.000
VCR 0.000
ACD-A 0.000
Olomoucine 0.000
Bestatin 0.000
Wellferon 0.000
Vatalanib 0.000
Temodal 0.000
Orthoclone OKT3 0.000
Calcium gluconate 0.000
more...
Enzyme
focal adhesion kinase 0.011
BMT 0.002
ERK 0.000
TdT 0.000
CD13 0.000
reverse transcriptase 0.000
P-glycoprotein 0.000
caspase-3 0.000
EC 2.4.99.4 0.000
mitogen-activated protein kinase 0.000
EC 2.4.1.102 0.000
PARP 0.000
CD10 0.000
alkaline phosphatase 0.000
peroxidase 0.000
protein kinase 0.000
IMP dehydrogenase 0.000
MEK 0.000
farnesyltransferase 0.000
caspase-9 0.000
transcriptase 0.000
farnesyltransferase 0.000
asparaginase 0.000
proteasome 0.000
arachidonate 5-lipoxygenase 0.000
homocysteine methyltransferase 0.000
proteinase-3 0.000
alpha-2-L-fucosyltransferase 0.000
HK3 0.000
RNA polymerase 0.000
alpha-N-acetylglucosaminyl phosphodiesterase 0.000
LTC4 synthase 0.000
phosphatidylinositol 3-kinase 0.000
caspase-8 0.000
glucose-6-phosphate dehydrogenase 0.000
methionine decarboxylase 0.000
CYP3A4 0.000
phosphoinositide 3-kinase 0.000
alpha-galactosyltransferase 0.000
cdc2 0.000
N-acetylglucosaminyltransferase III 0.000
adenosine deaminase 0.000
topoisomerase 0.000
NQO2 0.000
Ap4A hydrolase 0.000
adenosine deaminase 0.000
12-lipoxygenase 0.000
glycoprotease 0.000
GMP reductase 0.000
caspase-1 0.000
nicotinamide mononucleotide adenylyltransferase 0.000
topoisomerase 0.000
MDR 0.000
DHAD 0.000
STK 0.000
lactate dehydrogenase 0.000
lysozyme 0.000
RNase 0.000
acid phosphatase 0.000
STR 0.000
luciferase 0.000
sialyltransferase 0.000
sialyltransferase 0.000
sialyltransferase 0.000
tryptase 0.000
RNase 0.000
cystathionine beta-synthase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
calcineurin 0.000
endo-beta-galactosidase 0.000
CMP kinase 0.000
hypoxanthine-guanine phosphoribosyltransferase 0.000
GD3 synthase 0.000
separase 0.000
neutrophil collagenase 0.000
caspase-2 0.000
Omi/HtrA2 0.000
MIP 0.000
cathepsin G 0.000
caspase-2 0.000
more...
Compound
ABL 0.062
BCR 0.061
Busulfan 0.001
Homoharringtonine 0.000
Ara-C 0.000
Ara-C 0.000
tyrosine 0.000
pentosidine 0.000
Indirubin 0.000
Hydroxyurea 0.000
KT-1 0.000
Tiazofurin 0.000
DNA 0.000
TBI 0.000
lysine 0.000
TEL 0.000
DADI 0.000
MCNU 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
C7H14N2 0.000
Tyrosine 0.000
S-(carboxymethyl)cysteine 0.000
S-(carboxymethyl)cysteine 0.000
AGE 0.000
Mafosfamide 0.000
C15H12O2 0.000
2-imino-1,3-thiazolidin-4-one 0.000
2-imino-1,3-thiazolidin-4-one 0.000
C7H14N2 0.000
C7H14N2 0.000
[1,1'-biphenyl]-2-carboxylic acid 0.000
Taxodione 0.000
5-Aza-2'-deoxycytidine 0.000
Dec 0.000
C7H14N2 0.000
Norlichexanthone 0.000
C7H14N2 0.000
alpha-Curcumene 0.000
Clin 0.000
cephalotaxine 0.000
MTT 0.000
cephalotaxine 0.000
retinoic acid 0.000
3-quinolinecarbonitrile 0.000
LTC4 0.000
VP-16 0.000
pentos-2-ulose 0.000
pentos-2-ulose 0.000
Mitoxantrone 0.000
9-isothiocyanatoacridine 0.000
DBM 0.000
2-acetylbenzoic acid 0.000
4-acetylbenzoic acid 0.000
Caracemide 0.000
Methotrexate 0.000
Mitoxantrone 0.000
MTX 0.000
RPCNU 0.000
Carbidopa-levodopa 0.000
Herbimycin 0.000
Calotropin 0.000
Berbamine 0.000
Calotropin 0.000
Poncirin 0.000
Isopimpinellin 0.000
Aristeromycin 0.000
C20H24N2O2 0.000
3,4-pyridinedicarboxylic acid 0.000
Calotropin 0.000
ATP 0.000
Glycolaldehyde 0.000
Bruceine D 0.000
MEK 0.000
more...