Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023473 (chronic myeloid leukemia)
 18,916 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
BCR/ABL p210 fusion protein 10.7
MPD6 10.7
solute carrier family 26, member 11 10.7
ZNF78L1 10.7
protein tyrosine phosphatase, receptor type, f polypeptide 10.7
NME2 protein 10.7
Bcd orf1 10.7
CML 10.7
vacuolar sorting protein 28 10.7
BCR-ABL fusion protein 10.4
BCR/ABL fusion 10.3
BCR-ABL fusion 10.3
bcr 10.1
p210 10.1
AHI-1 10.1
BCR/ABL1 fusion 10.1
AML1/MDS1 10.1
BCR-ABL1 10.1
BCR/ABL fusion protein 10.1
BCR/ABL protein 10.0
BCR/ABL 10.0
ABL 10.0
Ribosomal protein S27a 10.0
breakpoint cluster region 9.9
HLA class II DRB1 antigen 9.7
Bomapin 9.7
IFN1@ 9.7
ABL1 protein 9.7
RNA binding motif protein 15 9.7
CXorf48 9.7
SCAM-1 9.7
ankyrin repeat domain-containing protein 26 9.7
Ets variant gene 6 9.7
PCTK3 9.7
P210 9.6
c-abl 9.5
c-ABL 9.5
BCR 9.5
ABL1 9.5
bcr/abl 9.4
FAM13A1 9.1
TYKi 9.1
GGTLA1 9.1
Mast cell growth factor 9.1
JTK5 9.1
BCR protein 9.1
CMPD 8.9
DR-nm23 8.9
CRKL 8.8
FAM133B 8.7
ZC3H15 8.7
CML66 8.7
CRK-II 8.7
SNAMA 8.7
interferon induced transmembrane protein 1 8.7
RNF217 8.7
HSJ2 8.7
C-abl 8.7
AGPAT2 protein 8.7
KLEIP 8.7
P15 protein 8.7
ATP-dependent RNA helicase DDX3X 8.7
PI4K2B 8.7
GGTLA4 8.7
OR51B5 8.7
EVI-1 8.6
CRKL protein 8.6
Breakpoint cluster region protein 8.6
CEL 8.6
Tyrosine kinase 8.4
BAF60B 8.4
MLF2 8.4
oxysterol binding protein-related protein 3 8.4
HLA class I alpha chain 8.4
CML1 8.4
ZNF77 8.4
KBTBD11 8.4
OR2AT4 8.4
BEX5 8.4
IGLC1 8.4
more...
Disease
Chronic myeloid leukemia in myeloid blast crisis 10.7
Acute erythremia 10.7
ALL, adult T-cell 10.7
Disseminated atypical mycobacterial infection 10.7
chronic myeloid leukemia 10.7
stage, hairy cell leukemia 10.7
childhood chronic myelogenous leukemia 10.7
CML progression 10.7
refractory CML 10.6
chronic phase CML 10.5
blast crisis 10.5
accelerated phase CML 10.5
relapsed CML 10.4
Ph- CML 10.4
Philadelphia chromosome positive chronic myelogenous leukemia 10.3
Ph-positive acute lymphoblastic leukemia 10.0
Philadelphia chromosome positive 10.0
ABL 9.9
shoulder synovitis 9.7
Myeloblastoma 9.7
stage I chronic lymphocytic leukemia 9.7
nonhematologic cancer 9.4
oligocythemia 9.1
Morganella morganii infection 9.1
Monosomy 7 syndrome 9.1
chronic myeloproliferative disorders 9.1
atypical chronic myeloid leukemia 8.9
Myeloproliferation 8.9
CMML-2 8.9
osteomyelofibrosis 8.8
chronic neutrophilic leukemia 8.8
osteomyelosclerosis 8.8
Therapy-related acute myeloid leukemia and myelodysplastic syndrome 8.7
Acute leukemia of ambiguous lineage 8.7
Paraneoplastic vasculitis 8.7
diseases; multiple 8.7
CMML-1 8.5
Eosinophilic leukemia 8.5
chronic eosinophilic leukemia 8.5
chronic leukemia 8.4
Myelomonocytic leukemia 8.4
Chloroma 8.4
myeloproliferative disorders 8.2
Secondary erythromelalgia 8.1
Sinus Histiocytosis 8.1
acute undifferentiated leukemia 8.1
essential thrombocythemia 7.9
Lymphocytic lymphoma 7.9
chronic undifferentiated schizophrenia 7.9
Meningeal leukemia 7.9
total bilateral blindness 7.9
CMD1 7.8
chloroma 7.8
primary myelofibrosis 7.8
Secondary hemochromatosis 7.7
Central nervous system leukemia 7.7
relapsed testicular cancer 7.7
polycythemia vera 7.7
Leukemia stem cell 7.7
chloroma 7.6
acute nonlymphocytic leukemia 7.6
Apocrine adenocarcinoma 7.5
Sickle cell retinopathy 7.5
Placental infarction 7.5
Autoimmune hypothyroidism 7.5
panmyelosis 7.5
chronic myelomonocytic leukemia 7.5
trisomy 8 7.4
Clonal evolution 7.4
FAB M4 7.3
secondary myelofibrosis 7.3
Leukemia relapse 7.3
acute lymphoblastic leukemia 7.3
psoitis 7.3
Leukemia cutis 7.3
Red cell aplasia 7.3
FAB M4Eo 7.3
FAB M2 7.2
myeloid leukemia 7.1
acute leukemia 7.1
more...
Symptom
No respiratory symptoms 8.7
Roth spots 6.5
Mental status changes 6.5
chromosome marker 6.4
pubic pain 5.7
Pain and tenderness 5.6
muscle cramps 5.5
periorbital edema 5.5
splenomegaly 5.4
Flu-like symptoms 4.9
swollen leg 4.9
non-productive cough 4.9
nipple pain 4.9
nipple pain 4.9
abdominal fullness 4.6
hepatosplenomegaly 4.5
Lhermitte's sign 4.3
localized edema 4.0
facial droop 3.7
intestinal bleeding 3.6
bone pain 3.6
generalized rash 3.6
Severe pain 3.4
arm weakness 3.2
nausea and vomiting 3.1
hepatomegaly 3.1
giddiness 3.1
giddiness 3.1
dry skin 3.1
rigors 3.0
rales 3.0
abnormal breathing 3.0
forgetfulness 2.9
abdominal discomfort 2.8
asthenia 2.7
HSA 2.6
Gastrointestinal symptoms 2.5
night sweats 2.5
nausea 2.5
Fluctuation 2.5
No adverse effect 2.4
myalgia 2.4
hip pain 2.2
prostration 2.2
hypoproteinemia 2.2
consciousness disturbance 2.0
orthopnea 1.9
anorexia 1.9
chills 1.8
dysesthesia 1.8
tenesmus 1.8
paresthesia 1.8
otalgia 1.7
diarrhea 1.7
syncopal episodes 1.7
arthralgia 1.7
lightheadedness 1.7
shortness of breath 1.7
dyspnea 1.7
vomiting 1.7
personality change 1.6
productive cough 1.6
adenitis 1.6
decreased appetite 1.5
Ill 1.5
persistent cough 1.5
acute abdomen 1.4
fatigue 1.4
atypical chest pain 1.4
erythema 1.4
thigh pain 1.3
leg edema 1.3
right upper quadrant pain 1.3
blurred vision 1.3
chest tightness 1.1
cachexia 1.1
lethargy 1.0
dysuria 1.0
pallor 1.0
exertional dyspnea 1.0
more...
Drug
Bosutinib 10.1
Starasid 9.7
Gleevec 9.7
Imatinib 9.6
Dasatinib 9.6
Tiazofurine 9.1
Dacogen 8.6
Troxacitabine 8.3
Sobuzoxane 8.1
Roferon A 7.9
Ranimustine 7.9
Vindesine 7.3
Vindesine 7.3
Anagrelide 7.2
BZQ 6.9
Interferon alfa-2a 6.9
MDS 6.9
Genasense 6.9
Intron A 6.9
KCL 6.9
Intron A 6.9
Intron A 6.8
Tetradecane 6.8
Cianidanol 6.8
Roquinimex 6.8
Piriprost 6.6
Tipifarnib 6.6
Oncophage 6.5
Hoelen 6.4
TEL 6.2
Radicicol 6.2
Forodesine 6.2
TRM 6.2
Azacytidine 6.2
ARA-C 6.0
anti-CD33 6.0
Lenograstim 6.0
Tykerb 5.9
Acadesine 5.8
Nelarabine 5.7
Thioguanine 5.7
Proleukin 5.6
Campath 5.6
Campath 5.6
Idarubicin 5.6
Nexavar 5.6
G-CSF 5.5
Antithymocyte globulin 5.3
ACD-A 5.3
Olomoucine 5.3
Vatalanib 5.2
Wellferon 5.2
Temodal 5.2
Clofarabine 5.2
Fludarabine 5.2
Orthoclone OKT3 5.1
Sunitinib malate 5.1
Calcium gluconate 5.1
Allegra 5.0
Allegra 5.0
Arsenic trioxide 5.0
CXM 5.0
Lantus 5.0
Cerezyme 4.9
4-Hydroxytamoxifen 4.9
Arava 4.8
Novantrone 4.7
Flavopiridol 4.6
Thrombostat 4.6
Bestatin 4.6
Chymopapain 4.5
Timentin 4.5
Tarceva 4.5
Ceredase 4.5
Pyridoxamine 4.5
VCR 4.4
Lipitor 4.4
Orphan 4.2
Navelbine 4.2
Furan 4.2
more...
Enzyme
EC 2.4.99.4 8.4
EC 2.4.1.102 8.0
BMT 7.5
focal adhesion kinase 6.9
alpha-2-L-fucosyltransferase 6.0
HK3 5.9
alpha-N-acetylglucosaminyl phosphodiesterase 5.9
TdT 5.6
methionine decarboxylase 5.5
arachidonate 5-lipoxygenase 5.5
alpha-galactosyltransferase 5.4
LTC4 synthase 5.4
homocysteine methyltransferase 5.3
CD13 5.1
N-acetylglucosaminyltransferase III 5.1
Ap4A hydrolase 5.1
IMP dehydrogenase 5.1
GMP reductase 4.9
proteinase-3 4.9
farnesyltransferase 4.9
glycoprotease 4.8
DHAD 4.7
nicotinamide mononucleotide adenylyltransferase 4.7
NQO2 4.7
STK 4.5
CMP kinase 4.4
farnesyltransferase 4.3
GD3 synthase 4.2
neutrophil collagenase 4.1
serine acetyltransferase 4.0
endo-beta-galactosidase 4.0
DAP II 3.9
separase 3.9
Omi/HtrA2 3.9
P-glycoprotein 3.9
asparaginase 3.8
12-lipoxygenase 3.8
CD10 3.6
UMP kinase 3.5
IOR 3.5
PARP 3.5
caspase-2 3.4
deoxyhypusine synthase 3.4
inosine triphosphatase 3.4
cysteine synthase 3.4
factor C 3.4
glycine N-methyltransferase 3.4
N-acetylglucosaminyltransferase V 3.4
caspase-9 3.4
betaine-homocysteine methyltransferase 3.4
reverse transcriptase 3.4
cystathionine beta-synthase 3.4
alpha-N-acetylgalactosaminidase 3.4
caspase-2 3.4
endo-beta-galactosidase 3.3
inositol phosphatase 3.3
Fpg protein 3.3
cystathionine gamma-lyase 3.3
caspase-10 3.2
ERK 3.2
CLK1 3.2
nicotinamide phosphoribosyltransferase 3.2
transcriptase 3.2
caspase-10 3.2
caspase-3 3.2
sialyltransferase 3.1
sialyltransferase 3.1
sialyltransferase 3.1
MCS 3.1
chymopapain 3.0
succinyl-CoA synthetase 3.0
caspase-4 3.0
acetylesterase 3.0
uridine kinase 3.0
porphobilinogen deaminase 3.0
chymopapain 3.0
MEK 2.9
CGT 2.9
caspase-7 2.9
cathepsin G 2.9
more...
Compound
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
C7H14N2 10.7
2-imino-1,3-thiazolidin-4-one 9.7
C15H12O2 9.7
C7H14N2 9.7
C7H14N2 9.7
2-imino-1,3-thiazolidin-4-one 9.7
DADI 9.7
ABL 9.6
BCR 9.5
Norlichexanthone 9.1
alpha-Curcumene 9.1
C7H14N2 9.1
C7H14N2 9.1
Homoharringtonine 8.9
KT-1 8.8
Taxodione 8.7
S-(carboxymethyl)cysteine 8.5
S-(carboxymethyl)cysteine 8.5
pentos-2-ulose 8.4
pentos-2-ulose 8.4
[1,1'-biphenyl]-2-carboxylic acid 8.4
Tiazofurin 8.1
9-isothiocyanatoacridine 8.1
Indirubin 8.1
Busulfan 8.0
Mafosfamide 7.9
4-acetylbenzoic acid 7.9
Caracemide 7.9
2-acetylbenzoic acid 7.9
3-quinolinecarbonitrile 7.8
RPCNU 7.7
Carbidopa-levodopa 7.7
Calotropin 7.5
Poncirin 7.4
Isopimpinellin 7.4
Calotropin 7.4
MCNU 7.4
Aristeromycin 7.3
Calotropin 7.3
3,4-pyridinedicarboxylic acid 7.3
C20H24N2O2 7.3
cephalotaxine 7.2
Bruceine D 7.1
cephalotaxine 7.1
pentosidine 7.0
RFCNU 7.0
Indicine N-oxide 7.0
Justicidin B 7.0
Berbamine 6.8
Ovatodiolide 6.8
TMCA 6.7
Fangchinoline 6.7
Ara-C 6.6
N tau-methylimidazoleacetic acid 6.5
Hydroxyurea 6.5
Pyrvinium 6.5
Dehydrocostus lactone 6.5
Ara-C 6.4
2-Hydroxyglutarate 6.4
TMCA 6.4
N-Acetyl-D-galactosamine 6.4
Glycolaldehyde 6.4
PGD3 6.3
TEL 6.2
Tomatidine 6.1
methyl decanoate 6.1
SCMC 6.1
Hydrocortisone acetate 6.1
4-Hydroperoxycyclophosphamide 6.1
Tomatidine 6.1
Tetrahydrouridine 6.0
Rocaglamide 6.0
more...