Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0023473 (chronic myeloid leukemia)
18,916 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tyrosine kinase 3291 CML 3246 BCR 2720 ABL 2629 Sep 1219 lymphoid 946 bcr 941 HLA 799 BCR-ABL1 786 interferon 747 AML 699 BCR/ABL 657 Mol 646 ALL 632 CD34 537 IFN 480 erythroid 429 breakpoint cluster region 373 interferon-alpha 354 bcr/abl 326 granulocyte 305 p210 299 p53 287 cytokine 281 BCR-ABL fusion 261 ABL1 255 Tyrosine kinase 235 caspase-3 225 non-Hodgkin's lymphoma 221 c-abl 210 JAK2 198 ATP 198 hemoglobin 188 She 185 c-kit 178 Bcl-2 177 BCR/ABL fusion 172 CLL 171 FISH 170 interferon alpha 169 MDS 157 STAT5 156 CD8 149 G-CSF 144 granulocyte-macrophage 143 alkaline phosphatase 140 granulocyte colony-stimulating factor 137 KIT 136 fused 135 collagen 131 AKT 129 p190 129 CD4 125 IL-3 123 HLA-DR 121 MAPK 117 P-glycoprotein 113 megakaryocyte 113 proto-oncogene 113 protein tyrosine kinase 111 p21 110 mTOR 109 PI3K 108 P210 104 tumor necrosis factor 104 CD33 99 FAB 99 GM-CSF 98 ERK 98 CD38 95 erythropoietin 94 myeloperoxidase 92 human leukocyte antigen 92 platelet-derived growth factor receptor 90 granulocyte-macrophage colony-stimulating factor 89 CSF 89 glycoprotein 86 STAT 85 PHA 84 HLA-A 84 more...

Disease chronic myeloid leukemia 18916 leukemia 4580 cancer 4503 acute myeloid leukemia 2674 ABL 2629 blast crisis 2195 acute lymphoblastic leukemia 2017 tumor 1663 lymphoma 1227 myelodysplastic syndrome 948 Leukemia 896 graft-versus-host disease 886 myeloproliferative disorders 874 acute leukemia 759 chronic lymphocytic leukemia 674 multiple myeloma 563 chronic lymphocytic leukemia 542 hematologic malignancies 452 polycythemia vera 417 Hodgkin's disease 372 essential thrombocythemia 359 minimal residual disease 354 myeloid leukemia 334 chronic phase CML 327 myelofibrosis 301 non-Hodgkin's lymphoma 294 thrombocytosis 287 lymphoblastic leukemia 282 leukemogenesis 276 primary myelofibrosis 269 acute promyelocytic leukemia 261 thrombocytopenia 256 anemia 241 aplastic anemia 232 diabetes 187 residual disease 186 breast cancer 169 acute nonlymphocytic leukemia 165 stromal tumors 164 carcinoma 160 melanoma 160 MDS 157 Philadelphia chromosome positive 154 chronic myeloproliferative disorders 152 chronic myelomonocytic leukemia 142 myelosuppression 140 neutropenia 137 sarcoma 135 tumorigenesis 132 cytomegalovirus 122 hairy cell leukemia 117 interstitial pneumonia 105 tumor progression 102 trisomy 8 102 pneumonia 100 sepsis 98 tumor growth 96 T-cell acute lymphoblastic leukemia 94 eosinophilia 93 WT1 91 B-ALL 89 lung cancer 87 PHA 84 Burkitt's lymphoma 81 chronic leukemia 80 chloroma 80 SCID 80 pancytopenia 78 rash 78 CML progression 78 SCT 75 Epstein 75 hypertension 74 sepsis 74 lymphadenopathy 74 adenocarcinoma 71 gastrointestinal stromal tumor 70 B-cell lymphoma 69 erythroleukemia 68 carcinogenesis 67 more...

Symptom splenomegaly 247 diarrhea 114 fatigue 83 nausea 78 pain 71 vomiting 60 hepatosplenomegaly 58 headache 55 dyspnea 53 nausea and vomiting 50 weakness 36 abdominal pain 34 hepatomegaly 30 anorexia 30 muscle cramps 25 cough 23 bone pain 22 myalgia 20 erythema 20 Ill 19 arthralgia 14 seizures 14 respiratory distress 11 chest pain 11 HSA 11 exhaustion 10 shortness of breath 10 back pain 10 paresthesia 10 discomfort 10 asthenia 10 constipation 10 discomfort 10 chills 9 collapse 9 starvation 9 cachexia 7 anesthesia 7 chromosome marker 7 periorbital edema 7 lethargy 7 abdominal discomfort 7 abdominal fullness 6 intestinal bleeding 6 dizziness 6 vertigo 6 acute abdomen 5 hip pain 5 non-productive cough 5 dry skin 5 rigors 4 exertional dyspnea 4 sleepiness 4 syncope 4 tinnitus 4 night sweats 4 acidity 4 insomnia 4 hemoptysis 3 rales 3 blurred vision 3 thinning 3 dysuria 3 pallor 3 overweight 3 paresis 3 forgetfulness 3 hypoproteinemia 3 tremor 3 ataxia 3 numbness 3 flushing 2 oliguria 2 agitation 2 Fluctuation 2 ophthalmoplegia 2 Gastrointestinal symptoms 2 dysarthria 2 spasm 2 dysesthesia 2 more...

Drug Imatinib 1143 Gleevec 690 lysine 368 Dasatinib 276 CSF 170 MDS 157 G-CSF 144 Dermatol 86 IFN-gamma 76 IL-2 69 Bosutinib 61 Leaf 51 ROS 48 TEL 35 CTX 30 Arsenic trioxide 25 Campath 22 Campath 22 ADM 20 KCL 19 Cardiovasc 19 ABC 17 Herceptin 17 Adriamycin 16 Monit 16 TRM 16 G418 16 ADR 15 Gel 14 anti-CD33 13 Hypaque 12 ascorbate 12 Bortezomib 12 Hypaque 12 vitamin E 12 CTX 11 Vindesine 11 MAP 11 Vindesine 11 VCR 11 CTX 11 Etoposide 10 -deoxyadenosine 10 Gefitinib 10 MRC 10 Fludarabine 10 Rituximab 10 Intron A 9 ARA-C 9 AraC 9 Intron A 9 Asn 8 Dial 8 THF 8 Anagrelide 8 VCR 8 Intron A 8 Heme 8 ROC 8 Prednisolone 7 Sorafenib 7 Orphan 6 IFN-beta 6 Adenosine deaminase 6 Idarubicin 6 PTH 6 NVP 5 Ranitidine 5 TTC 5 AZT 5 ENT 5 NBT 5 Asthma 5 Dacogen 5 AZT 5 LCM 4 Troxacitabine 4 Azacytidine 4 Fragment 4 LCM 4 more...

Enzyme focal adhesion kinase 3051 ERK 526 mitogen-activated protein kinase 293 BMT 278 reverse transcriptase 198 caspase-3 190 protein kinase 181 peroxidase 164 alkaline phosphatase 141 P-glycoprotein 116 PARP 89 MEK 83 CD13 75 CD10 70 proteasome 68 RNA polymerase 67 TdT 55 transcriptase 51 caspase-9 47 luciferase 44 protein kinase C 43 lactate dehydrogenase 40 phosphatidylinositol 3-kinase 36 lysozyme 34 RNase 31 trypsin 30 superoxide dismutase 30 catalase 29 glucose-6-phosphate dehydrogenase 29 caspase-8 28 calcineurin 28 topoisomerase 28 RNase 28 cdc2 27 acid phosphatase 26 alanine aminotransferase 26 ATPase 25 topoisomerase 24 CYP3A4 24 DNA polymerase 23 glutathione S-transferase 23 phosphoinositide 3-kinase 23 asparaginase 23 thrombin 22 neuraminidase 21 caspase-1 20 adenosine deaminase 20 aspartate aminotransferase 19 adenosine deaminase 19 AMPK 19 AMP-activated protein kinase 19 farnesyltransferase 18 IMP dehydrogenase 18 farnesyltransferase 18 glyceraldehyde-3-phosphate dehydrogenase 17 elastase 16 MDR 16 AMPK 14 MIP 14 ACS 13 DNA methyltransferase 13 endonuclease 13 NADPH oxidase 12 neutrophil elastase 12 NADPH oxidase 12 STR 12 GSK 11 tryptase 11 IKK 11 carboxylesterase 10 plasmin 10 hypoxanthine-guanine phosphoribosyltransferase 10 glyceraldehyde-3-phosphate dehydrogenase 9 ribonucleotide reductase 9 gamma-glutamyl transpeptidase 9 urokinase-type plasminogen activator 9 glyceraldehyde-3-phosphate dehydrogenase 9 protein phosphatase 2A 9 MAP 9 dihydrofolate reductase 9 more...

Compound BCR 2720 ABL 2629 DNA 1442 Dec 1313 Clin 1100 tyrosine 648 lysine 379 oxygen 234 ATP 198 glucose 177 MTT 152 retinoic acid 128 water 116 calcium 113 Ara-C 107 sodium 98 acetate 95 Ara-C 92 phosphate 90 serine 86 His 86 Busulfan 76 iron 73 TBI 72 threonine 72 arginine 72 Tyrosine 70 Hydroxyurea 62 MEK 59 cysteine 57 leucine 56 iodine 54 methionine 50 TNF 49 pentosidine 48 GTP 48 Methotrexate 46 pyrimidine 44 SDS 44 pyrimidine 43 hydrogen 43 Phe 43 VP-16 42 bromide 41 ADP 41 LTC4 40 sulfate 40 silver 39 GSH 37 GSH 37 galactose 37 nitrogen 36 ADP 35 TEL 35 ADP 35 Cyclosporine 34 creatinine 33 MDA 33 AGE 33 PEG 32 urea 32 methanol 31 Optimal 30 CTX 30 MTX 30 benzene 29 zinc 29 THP 28 nitric oxide 28 THP 28 Pac 28 PAS 27 Homoharringtonine 27 copper 25 Asp 25 Ile 25 salt 25 PEG 24 alanine 24 acridine 23 more...

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