Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023473 (chronic myeloid leukemia)
18,916 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tyrosine kinase 3291
CML 3246
BCR 2720
ABL 2629
Sep 1219
lymphoid 946
bcr 941
HLA 799
BCR-ABL1 786
interferon 747
AML 699
BCR/ABL 657
Mol 646
ALL 632
CD34 537
IFN 480
erythroid 429
breakpoint cluster region 373
interferon-alpha 354
bcr/abl 326
granulocyte 305
p210 299
p53 287
cytokine 281
BCR-ABL fusion 261
ABL1 255
Tyrosine kinase 235
caspase-3 225
non-Hodgkin's lymphoma 221
c-abl 210
ATP 198
JAK2 198
hemoglobin 188
She 185
c-kit 178
Bcl-2 177
BCR/ABL fusion 172
CLL 171
FISH 170
interferon alpha 169
more...
Disease
chronic myeloid leukemia 18916
leukemia 4580
cancer 4503
acute myeloid leukemia 2674
ABL 2629
blast crisis 2195
acute lymphoblastic leukemia 2017
tumor 1663
lymphoma 1227
myelodysplastic syndrome 948
Leukemia 896
graft-versus-host disease 886
myeloproliferative disorders 874
acute leukemia 759
chronic lymphocytic leukemia 674
multiple myeloma 563
chronic lymphocytic leukemia 542
hematologic malignancies 452
polycythemia vera 417
Hodgkin's disease 372
essential thrombocythemia 359
minimal residual disease 354
myeloid leukemia 334
chronic phase CML 327
myelofibrosis 301
non-Hodgkin's lymphoma 294
thrombocytosis 287
lymphoblastic leukemia 282
leukemogenesis 276
primary myelofibrosis 269
acute promyelocytic leukemia 261
thrombocytopenia 256
anemia 241
aplastic anemia 232
diabetes 187
residual disease 186
breast cancer 169
acute nonlymphocytic leukemia 165
stromal tumors 164
carcinoma 160
more...
Symptom
splenomegaly 247
diarrhea 114
fatigue 83
nausea 78
pain 71
vomiting 60
hepatosplenomegaly 58
headache 55
dyspnea 53
nausea and vomiting 50
weakness 36
abdominal pain 34
hepatomegaly 30
anorexia 30
muscle cramps 25
cough 23
bone pain 22
erythema 20
myalgia 20
Ill 19
arthralgia 14
seizures 14
respiratory distress 11
chest pain 11
HSA 11
exhaustion 10
asthenia 10
discomfort 10
shortness of breath 10
paresthesia 10
constipation 10
back pain 10
discomfort 10
collapse 9
chills 9
starvation 9
cachexia 7
periorbital edema 7
abdominal discomfort 7
chromosome marker 7
more...
Drug
Imatinib 1143
Gleevec 690
lysine 368
Dasatinib 276
CSF 170
MDS 157
G-CSF 144
Dermatol 86
IFN-gamma 76
IL-2 69
Bosutinib 61
Leaf 51
ROS 48
TEL 35
CTX 30
Arsenic trioxide 25
Campath 22
Campath 22
ADM 20
KCL 19
Cardiovasc 19
Herceptin 17
ABC 17
Adriamycin 16
G418 16
TRM 16
Monit 16
ADR 15
Gel 14
anti-CD33 13
Bortezomib 12
Hypaque 12
Hypaque 12
vitamin E 12
ascorbate 12
MAP 11
VCR 11
CTX 11
Vindesine 11
Vindesine 11
more...
Enzyme
focal adhesion kinase 3051
ERK 526
mitogen-activated protein kinase 293
BMT 278
reverse transcriptase 198
caspase-3 190
protein kinase 181
peroxidase 164
alkaline phosphatase 141
P-glycoprotein 116
PARP 89
MEK 83
CD13 75
CD10 70
proteasome 68
RNA polymerase 67
TdT 55
transcriptase 51
caspase-9 47
luciferase 44
protein kinase C 43
lactate dehydrogenase 40
phosphatidylinositol 3-kinase 36
lysozyme 34
RNase 31
trypsin 30
superoxide dismutase 30
glucose-6-phosphate dehydrogenase 29
catalase 29
caspase-8 28
RNase 28
calcineurin 28
topoisomerase 28
cdc2 27
alanine aminotransferase 26
acid phosphatase 26
ATPase 25
CYP3A4 24
topoisomerase 24
phosphoinositide 3-kinase 23
more...
Compound
BCR 2720
ABL 2629
DNA 1442
Dec 1313
Clin 1100
tyrosine 648
lysine 379
oxygen 234
ATP 198
glucose 177
MTT 152
retinoic acid 128
water 116
calcium 113
Ara-C 107
sodium 98
acetate 95
Ara-C 92
phosphate 90
serine 86
His 86
Busulfan 76
iron 73
arginine 72
TBI 72
threonine 72
Tyrosine 70
Hydroxyurea 62
MEK 59
cysteine 57
leucine 56
iodine 54
methionine 50
TNF 49
GTP 48
pentosidine 48
Methotrexate 46
SDS 44
pyrimidine 44
Phe 43
more...