Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023473 (chronic myeloid leukemia)
 18,916 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The impact on human health of substances emitted to air by the Flemish industry was calculated with characterization factors (CFs) provided by the CML, Eco-indicator 99, EPS, EDIP and USEtox impact assessment methods. A comparison of the results pointed out that the choice of the CFs can greatly influence conclusions on the trend of the impact over time and on the relative contribution of the individual substances. If the impact on human health of organic substances and heavy metals was assessed separately, the differences between methods were less pronounced. In this case, the impacts on human health obtained by simply dividing the emitted masses of substances by the respective minimal risk concentrations or minimal risk doses, were comparable to those calculated with the CFs of the model-based methods.
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PMID:Assessment of the impact on human health of industrial emissions to air: does the result depend on the applied method? 2087 Mar 55

Recent legislation has stressed the need to decide the best end-of-life (EoL) option for post-consumer products considering their full life-cycle and the corresponding overall environmental impacts. The life cycle assessment (LCA) technique has become a common tool to evaluate those impacts. The present study aimed to contribute to the better understanding of the application of this technique, by evaluating the influence of the selection of the life cycle impact assessment (LCIA) method in its results and conclusions. A specific case study was chosen, using previous information related to an anti-glare lamellae (AGL) for highway use, made with virgin and recycled high-density polyethylene (HDPE). Five distinct LCIA methods were used: Eco-indicator 99, CML 2 (2000), EPS 2000, Eco-indicator 95 and EDIP 97. Consistent results between these methods were obtained for the Climate change, Ozone layer depletion, Acidification and Eutrophication environmental indicators. Conversely, the Summer smog indicator showed large discrepancies between impact assessment methods. The work sheds light on the advantages inherent in using various LCIA methods when doing the LCA study of a specific product, thus evidencing complementary analysis perspectives.
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PMID:Influence of the impact assessment method on the conclusions of a LCA study. Application to the case of a part made with virgin and recycled HDPE. 2155 83