Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0023467 (
acute myeloid leukemia
)
35,200
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AML
6155
Sep
2209
FLT3
1758
ALL
1382
CD34
1375
lymphoid
1243
Mol
1122
HLA
1057
FAB
1050
MLL
888
p53
832
NPM1
796
MDS
790
tyrosine kinase
769
CD33
734
cytokine
729
CML
699
RUNX1
672
AML1
628
erythroid
575
granulocyte
572
all-trans
535
granulocyte colony-stimulating factor
497
ETO
462
myeloperoxidase
462
c-fms
439
non-Hodgkin's lymphoma
438
G-CSF
430
tyrosine kinase 3
420
histone
413
CD13
399
p13
389
She
372
HLA-DR
372
GM-CSF
370
ara
366
Bcl-2
365
CEBPA
363
KIT
347
CR1
338
IDH1
336
chimeric protein
336
DNMT3A
335
PML
330
WT1
318
histone deacetylase
311
CD7
307
granulocyte-macrophage colony-stimulating factor
306
CSF
301
P-glycoprotein
301
receptor tyrosine kinase
292
CD19
290
CD4
287
CD38
285
IL-3
280
AKT
278
CD56
273
TET2
272
CD14
271
IDH2
270
SCT
269
caspase-3
266
fused
263
c-kit
263
hemoglobin
253
THP
250
CD8
247
AF9
242
p21
239
ABL
239
FISH
238
MYH11
238
BCR
236
mTOR
236
CD11b
232
JAK2
228
CD117
222
interferon
220
STAT5
219
ERK
213
more...
Disease
acute myeloid leukemia
35200
leukemia
11747
cancer
9744
myelodysplastic syndrome
5398
acute lymphoblastic leukemia
4042
tumor
3639
chronic myeloid leukemia
2674
acute leukemia
2517
Leukemia
2450
lymphoma
2318
acute nonlymphocytic leukemia
1439
leukemogenesis
1356
acute promyelocytic leukemia
1279
graft-versus-host disease
1246
hematologic malignancies
1062
minimal residual disease
891
chronic lymphocytic leukemia
840
multiple myeloma
836
myeloid leukemia
794
MDS
790
Hodgkin's disease
766
neutropenia
766
anemia
730
chronic lymphocytic leukemia
712
myeloproliferative disorders
648
thrombocytopenia
631
non-Hodgkin's lymphoma
569
sarcoma
546
blast crisis
516
lymphoblastic leukemia
490
pediatric AML
471
adult AML
468
chronic myelomonocytic leukemia
445
WT1
443
secondary AML
440
dysplasia
403
aplastic anemia
396
tumorigenesis
377
sepsis
370
breast cancer
367
pancytopenia
365
residual disease
347
PML
343
chloroma
342
T-cell acute lymphoblastic leukemia
334
myelosuppression
327
Down syndrome
306
sepsis
305
refractory anemia
294
pneumonia
287
fungal infection
273
SCT
269
tumor growth
261
acute monocytic leukemia
261
trisomy 8
257
RAEB
254
carcinoma
252
myelofibrosis
250
trisomy
248
B-cell lymphoma
239
ABL
239
Fanconi
220
polycythemia vera
214
SCID
205
B-ALL
203
melanoma
202
erythroleukemia
198
Best
197
aspergillosis
191
eosinophilia
179
solid tumor
167
childhood ALL
166
cytomegalovirus
163
lung cancer
162
AML/MDS
162
essential thrombocythemia
156
NOD
155
carcinogenesis
154
primary myelofibrosis
148
tumor progression
145
more...
Symptom
diarrhea
238
nausea
185
fatigue
174
vomiting
158
splenomegaly
155
pain
141
hepatosplenomegaly
88
dyspnea
81
abdominal pain
77
nausea and vomiting
75
headache
71
anorexia
59
cough
59
hepatomegaly
57
weakness
51
respiratory distress
46
erythema
38
seizures
37
fever of unknown origin
35
bone pain
34
Ill
33
exhaustion
33
chills
30
pallor
24
chest pain
23
constipation
21
hemoptysis
20
starvation
19
overweight
18
myalgia
18
back pain
18
lethargy
17
decreased appetite
16
sleepiness
16
anesthesia
16
arthralgia
15
shortness of breath
14
dizziness
13
acute abdomen
12
tachypnea
11
asthenia
11
polyuria
11
ataxia
11
rigors
10
paresthesia
10
epigastric pain
10
low back pain
9
numbness
9
vertigo
8
blurred vision
8
discomfort
8
discomfort
8
polydipsia
8
collapse
8
cerebellar ataxia
8
hemiplegia
8
flank pain
7
exertional dyspnea
7
paresis
7
sore throat
7
consciousness disturbance
6
right lower quadrant pain
6
acute abdominal pain
6
leg pain
5
shoulder pain
5
analgesia
5
thigh pain
5
syncope
5
productive cough
5
tremor
5
hypotonia
5
colic
4
flushing
4
dysarthria
4
night sweats
4
hoarseness
4
photophobia
4
ophthalmoplegia
4
insomnia
4
dry eye
4
more...
Drug
MDS
790
CSF
576
G-CSF
431
anti-CD33
249
lysine
173
Dermatol
139
IL-2
135
AraC
128
Leaf
125
TEL
103
MRC
89
ARA-C
87
ETS
63
Imatinib
61
Adriamycin
59
Arsenic trioxide
57
Clofarabine
57
CTX
54
TRM
52
IFN-gamma
50
ROS
49
Fludarabine
49
Etoposide
49
Idarubicin
48
Midostaurin
43
Sorafenib
41
Gleevec
40
Posaconazole
40
Lenalidomide
39
VCR
32
Monit
29
Retinoic acid
28
Bortezomib
28
NBT
26
LCM
24
VCR
24
LCM
24
ADR
23
ROC
23
p75
23
Rituximab
21
ABC
21
ADM
21
Campath
19
Campath
19
-deoxyadenosine
19
Cardiovasc
18
MAP
18
Alliance
17
ascorbate
16
Tipifarnib
16
Filgrastim
16
Azacytidine
16
TTC
16
Fluconazole
14
DNase I
14
Dasatinib
14
PE2
14
Filgrastim
13
Dacogen
12
GEO
12
Vorinostat
12
Histamine
11
IL-11
11
Erlotinib
11
Mutagen
11
Spectrum
11
Paraffin
11
CAM
11
uPA
10
NVP
10
Tacrolimus
10
Gel
10
CTX
10
CTX
10
Prednisolone
10
AmBisome
10
Glutathione
10
Isotretinoin
9
Asthma
9
more...
Enzyme
ERK
2629
focal adhesion kinase
674
peroxidase
625
mitogen-activated protein kinase
492
CD13
402
P-glycoprotein
301
BMT
294
reverse transcriptase
284
topoisomerase
282
topoisomerase
250
caspase-3
199
DNA methyltransferase
182
protein kinase
176
CD10
169
MEK
158
lactate dehydrogenase
135
isocitrate dehydrogenase
131
isocitrate dehydrogenase
131
PARP
127
proteasome
121
RNA polymerase
120
luciferase
118
TdT
109
lysozyme
103
protein kinase C
93
alkaline phosphatase
91
asparaginase
86
transcriptase
70
caspase-8
70
phosphatidylinositol 3-kinase
67
MDR
66
caspase-9
62
demethylase
58
cdc2
50
DNA polymerase
50
deoxycytidine kinase
49
alanine aminotransferase
47
trypsin
45
histone acetyltransferase
45
calcineurin
44
glutathione S-transferase
43
farnesyltransferase
42
farnesyltransferase
42
catalase
42
AMP-activated protein kinase
42
RNase
41
ACS
40
phosphoinositide 3-kinase
39
RNase
39
cytidine deaminase
36
acid phosphatase
36
neutrophil elastase
35
aldehyde dehydrogenase
33
granzyme B
32
GSK
31
carboxylesterase
30
AMPK
30
ATPase
30
ribonucleotide reductase
30
aspartate aminotransferase
30
ribonucleotide reductase
30
aldehyde dehydrogenase
28
aldehyde dehydrogenase
28
aldehyde dehydrogenase
28
aldehyde dehydrogenase
28
superoxide dismutase
27
AMPK
27
NQO1
27
thrombin
26
APC
26
neuraminidase
26
adenosine deaminase
25
adenosine deaminase
25
DAT
25
tryptase
25
thymidine kinase
25
CEP
24
caspase-1
24
urokinase-type plasminogen activator
24
CEP
24
more...
Compound
DNA
3152
Dec
2378
Clin
2005
retinoic acid
831
Ara-C
668
Ara-C
531
tyrosine
409
oxygen
368
THP
250
THP
250
ABL
239
BCR
236
lysine
208
acetate
195
MTT
186
benzene
179
VP-16
158
ATP
140
His
139
TNF
133
DFS
127
TBI
127
iron
126
serine
125
MEK
123
hydroxyglutarate
116
calcium
115
phosphate
110
5-Azacytidine
109
sodium
109
TEL
103
glucose
100
iodine
97
5-Aza-2'-deoxycytidine
97
arginine
93
CTP
89
leucine
78
cysteine
76
zinc
75
Adriamycin
74
creatinine
73
threonine
72
vitamin D
71
water
71
boron
71
DAC
70
Pac
68
2-oxoglutarate
68
pyrimidine
66
MDR
66
pyrimidine
66
Methotrexate
66
CPT
65
Daunorubicin
64
DEK
61
GTP
61
glutamine
57
nitrogen
57
Asp
57
Benzene
56
hydrogen
56
sulfate
55
CTX
54
urea
53
methionine
52
Mitoxantrone
49
m-AMSA
49
galactose
48
Mitoxantrone
48
isocitrate
47
Cyclosporine
47
AMP
47
SET
46
MTX
45
PAS
43
GSH
43
GSH
43
ACS
41
ADP
40
CAN
40
more...