Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023467 (acute myeloid leukemia)
35,200 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AML 6155
Sep 2209
FLT3 1758
ALL 1382
CD34 1375
lymphoid 1243
Mol 1122
HLA 1057
FAB 1050
MLL 888
p53 832
NPM1 796
MDS 790
tyrosine kinase 769
CD33 734
cytokine 729
CML 699
RUNX1 672
AML1 628
erythroid 575
granulocyte 572
all-trans 535
granulocyte colony-stimulating factor 497
ETO 462
myeloperoxidase 462
c-fms 439
non-Hodgkin's lymphoma 438
G-CSF 430
tyrosine kinase 3 420
histone 413
CD13 399
p13 389
She 372
HLA-DR 372
GM-CSF 370
ara 366
Bcl-2 365
CEBPA 363
KIT 347
CR1 338
IDH1 336
chimeric protein 336
DNMT3A 335
PML 330
WT1 318
histone deacetylase 311
CD7 307
granulocyte-macrophage colony-stimulating factor 306
CSF 301
P-glycoprotein 301
receptor tyrosine kinase 292
CD19 290
CD4 287
CD38 285
IL-3 280
AKT 278
CD56 273
TET2 272
CD14 271
IDH2 270
SCT 269
caspase-3 266
fused 263
c-kit 263
hemoglobin 253
THP 250
CD8 247
AF9 242
p21 239
ABL 239
FISH 238
MYH11 238
BCR 236
mTOR 236
CD11b 232
JAK2 228
CD117 222
interferon 220
STAT5 219
ERK 213
more...
Disease
acute myeloid leukemia 35200
leukemia 11747
cancer 9744
myelodysplastic syndrome 5398
acute lymphoblastic leukemia 4042
tumor 3639
chronic myeloid leukemia 2674
acute leukemia 2517
Leukemia 2450
lymphoma 2318
acute nonlymphocytic leukemia 1439
leukemogenesis 1356
acute promyelocytic leukemia 1279
graft-versus-host disease 1246
hematologic malignancies 1062
minimal residual disease 891
chronic lymphocytic leukemia 840
multiple myeloma 836
myeloid leukemia 794
MDS 790
Hodgkin's disease 766
neutropenia 766
anemia 730
chronic lymphocytic leukemia 712
myeloproliferative disorders 648
thrombocytopenia 631
non-Hodgkin's lymphoma 569
sarcoma 546
blast crisis 516
lymphoblastic leukemia 490
pediatric AML 471
adult AML 468
chronic myelomonocytic leukemia 445
WT1 443
secondary AML 440
dysplasia 403
aplastic anemia 396
tumorigenesis 377
sepsis 370
breast cancer 367
pancytopenia 365
residual disease 347
PML 343
chloroma 342
T-cell acute lymphoblastic leukemia 334
myelosuppression 327
Down syndrome 306
sepsis 305
refractory anemia 294
pneumonia 287
fungal infection 273
SCT 269
tumor growth 261
acute monocytic leukemia 261
trisomy 8 257
RAEB 254
carcinoma 252
myelofibrosis 250
trisomy 248
B-cell lymphoma 239
ABL 239
Fanconi 220
polycythemia vera 214
SCID 205
B-ALL 203
melanoma 202
erythroleukemia 198
Best 197
aspergillosis 191
eosinophilia 179
solid tumor 167
childhood ALL 166
cytomegalovirus 163
lung cancer 162
AML/MDS 162
essential thrombocythemia 156
NOD 155
carcinogenesis 154
primary myelofibrosis 148
tumor progression 145
more...
Symptom
diarrhea 238
nausea 185
fatigue 174
vomiting 158
splenomegaly 155
pain 141
hepatosplenomegaly 88
dyspnea 81
abdominal pain 77
nausea and vomiting 75
headache 71
anorexia 59
cough 59
hepatomegaly 57
weakness 51
respiratory distress 46
erythema 38
seizures 37
fever of unknown origin 35
bone pain 34
Ill 33
exhaustion 33
chills 30
pallor 24
chest pain 23
constipation 21
hemoptysis 20
starvation 19
overweight 18
myalgia 18
back pain 18
lethargy 17
decreased appetite 16
sleepiness 16
anesthesia 16
arthralgia 15
shortness of breath 14
dizziness 13
acute abdomen 12
tachypnea 11
asthenia 11
polyuria 11
ataxia 11
rigors 10
paresthesia 10
epigastric pain 10
low back pain 9
numbness 9
vertigo 8
blurred vision 8
discomfort 8
discomfort 8
polydipsia 8
collapse 8
cerebellar ataxia 8
hemiplegia 8
flank pain 7
exertional dyspnea 7
paresis 7
sore throat 7
consciousness disturbance 6
right lower quadrant pain 6
acute abdominal pain 6
leg pain 5
shoulder pain 5
analgesia 5
thigh pain 5
syncope 5
productive cough 5
tremor 5
hypotonia 5
colic 4
flushing 4
dysarthria 4
night sweats 4
hoarseness 4
photophobia 4
ophthalmoplegia 4
insomnia 4
dry eye 4
more...
Drug
MDS 790
CSF 576
G-CSF 431
anti-CD33 249
lysine 173
Dermatol 139
IL-2 135
AraC 128
Leaf 125
TEL 103
MRC 89
ARA-C 87
ETS 63
Imatinib 61
Adriamycin 59
Arsenic trioxide 57
Clofarabine 57
CTX 54
TRM 52
IFN-gamma 50
ROS 49
Fludarabine 49
Etoposide 49
Idarubicin 48
Midostaurin 43
Sorafenib 41
Gleevec 40
Posaconazole 40
Lenalidomide 39
VCR 32
Monit 29
Retinoic acid 28
Bortezomib 28
NBT 26
LCM 24
VCR 24
LCM 24
ADR 23
ROC 23
p75 23
Rituximab 21
ABC 21
ADM 21
Campath 19
Campath 19
-deoxyadenosine 19
Cardiovasc 18
MAP 18
Alliance 17
ascorbate 16
Tipifarnib 16
Filgrastim 16
Azacytidine 16
TTC 16
Fluconazole 14
DNase I 14
Dasatinib 14
PE2 14
Filgrastim 13
Dacogen 12
GEO 12
Vorinostat 12
Histamine 11
IL-11 11
Erlotinib 11
Mutagen 11
Spectrum 11
Paraffin 11
CAM 11
uPA 10
NVP 10
Tacrolimus 10
Gel 10
CTX 10
CTX 10
Prednisolone 10
AmBisome 10
Glutathione 10
Isotretinoin 9
Asthma 9
more...
Enzyme
ERK 2629
focal adhesion kinase 674
peroxidase 625
mitogen-activated protein kinase 492
CD13 402
P-glycoprotein 301
BMT 294
reverse transcriptase 284
topoisomerase 282
topoisomerase 250
caspase-3 199
DNA methyltransferase 182
protein kinase 176
CD10 169
MEK 158
lactate dehydrogenase 135
isocitrate dehydrogenase 131
isocitrate dehydrogenase 131
PARP 127
proteasome 121
RNA polymerase 120
luciferase 118
TdT 109
lysozyme 103
protein kinase C 93
alkaline phosphatase 91
asparaginase 86
transcriptase 70
caspase-8 70
phosphatidylinositol 3-kinase 67
MDR 66
caspase-9 62
demethylase 58
cdc2 50
DNA polymerase 50
deoxycytidine kinase 49
alanine aminotransferase 47
trypsin 45
histone acetyltransferase 45
calcineurin 44
glutathione S-transferase 43
farnesyltransferase 42
farnesyltransferase 42
catalase 42
AMP-activated protein kinase 42
RNase 41
ACS 40
phosphoinositide 3-kinase 39
RNase 39
cytidine deaminase 36
acid phosphatase 36
neutrophil elastase 35
aldehyde dehydrogenase 33
granzyme B 32
GSK 31
carboxylesterase 30
AMPK 30
ATPase 30
ribonucleotide reductase 30
aspartate aminotransferase 30
ribonucleotide reductase 30
aldehyde dehydrogenase 28
aldehyde dehydrogenase 28
aldehyde dehydrogenase 28
aldehyde dehydrogenase 28
superoxide dismutase 27
AMPK 27
NQO1 27
thrombin 26
APC 26
neuraminidase 26
adenosine deaminase 25
adenosine deaminase 25
DAT 25
tryptase 25
thymidine kinase 25
CEP 24
caspase-1 24
urokinase-type plasminogen activator 24
CEP 24
more...
Compound
DNA 3152
Dec 2378
Clin 2005
retinoic acid 831
Ara-C 668
Ara-C 531
tyrosine 409
oxygen 368
THP 250
THP 250
ABL 239
BCR 236
lysine 208
acetate 195
MTT 186
benzene 179
VP-16 158
ATP 140
His 139
TNF 133
DFS 127
TBI 127
iron 126
serine 125
MEK 123
hydroxyglutarate 116
calcium 115
phosphate 110
5-Azacytidine 109
sodium 109
TEL 103
glucose 100
iodine 97
5-Aza-2'-deoxycytidine 97
arginine 93
CTP 89
leucine 78
cysteine 76
zinc 75
Adriamycin 74
creatinine 73
threonine 72
vitamin D 71
water 71
boron 71
DAC 70
Pac 68
2-oxoglutarate 68
pyrimidine 66
MDR 66
pyrimidine 66
Methotrexate 66
CPT 65
Daunorubicin 64
DEK 61
GTP 61
glutamine 57
nitrogen 57
Asp 57
Benzene 56
hydrogen 56
sulfate 55
CTX 54
urea 53
methionine 52
Mitoxantrone 49
m-AMSA 49
galactose 48
Mitoxantrone 48
isocitrate 47
Cyclosporine 47
AMP 47
SET 46
MTX 45
PAS 43
GSH 43
GSH 43
ACS 41
ADP 40
CAN 40
more...