Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0023467 (
acute myeloid leukemia
)
35,200
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AML
6155
Sep
2209
FLT3
1758
ALL
1382
CD34
1375
lymphoid
1243
Mol
1122
HLA
1057
FAB
1050
MLL
888
p53
832
NPM1
796
MDS
790
tyrosine kinase
769
CD33
734
cytokine
729
CML
699
RUNX1
672
AML1
628
erythroid
575
granulocyte
572
all-trans
535
granulocyte colony-stimulating factor
497
myeloperoxidase
462
ETO
462
c-fms
439
non-Hodgkin's lymphoma
438
G-CSF
430
tyrosine kinase 3
420
histone
413
CD13
399
p13
389
She
372
HLA-DR
372
GM-CSF
370
ara
366
Bcl-2
365
CEBPA
363
KIT
347
CR1
338
more...
Disease
acute myeloid leukemia
35200
leukemia
11747
cancer
9744
myelodysplastic syndrome
5398
acute lymphoblastic leukemia
4042
tumor
3639
chronic myeloid leukemia
2674
acute leukemia
2517
Leukemia
2450
lymphoma
2318
acute nonlymphocytic leukemia
1439
leukemogenesis
1356
acute promyelocytic leukemia
1279
graft-versus-host disease
1246
hematologic malignancies
1062
minimal residual disease
891
chronic lymphocytic leukemia
840
multiple myeloma
836
myeloid leukemia
794
MDS
790
neutropenia
766
Hodgkin's disease
766
anemia
730
chronic lymphocytic leukemia
712
myeloproliferative disorders
648
thrombocytopenia
631
non-Hodgkin's lymphoma
569
sarcoma
546
blast crisis
516
lymphoblastic leukemia
490
pediatric AML
471
adult AML
468
chronic myelomonocytic leukemia
445
WT1
443
secondary AML
440
dysplasia
403
aplastic anemia
396
tumorigenesis
377
sepsis
370
breast cancer
367
more...
Symptom
diarrhea
238
nausea
185
fatigue
174
vomiting
158
splenomegaly
155
pain
141
hepatosplenomegaly
88
dyspnea
81
abdominal pain
77
nausea and vomiting
75
headache
71
cough
59
anorexia
59
hepatomegaly
57
weakness
51
respiratory distress
46
erythema
38
seizures
37
fever of unknown origin
35
bone pain
34
exhaustion
33
Ill
33
chills
30
pallor
24
chest pain
23
constipation
21
hemoptysis
20
starvation
19
myalgia
18
overweight
18
back pain
18
lethargy
17
decreased appetite
16
sleepiness
16
anesthesia
16
arthralgia
15
shortness of breath
14
dizziness
13
acute abdomen
12
tachypnea
11
more...
Drug
MDS
790
CSF
576
G-CSF
431
anti-CD33
249
lysine
173
Dermatol
139
IL-2
135
AraC
128
Leaf
125
TEL
103
MRC
89
ARA-C
87
ETS
63
Imatinib
61
Adriamycin
59
Arsenic trioxide
57
Clofarabine
57
CTX
54
TRM
52
IFN-gamma
50
ROS
49
Fludarabine
49
Etoposide
49
Idarubicin
48
Midostaurin
43
Sorafenib
41
Posaconazole
40
Gleevec
40
Lenalidomide
39
VCR
32
Monit
29
Bortezomib
28
Retinoic acid
28
NBT
26
LCM
24
LCM
24
VCR
24
ROC
23
p75
23
ADR
23
more...
Enzyme
ERK
2629
focal adhesion kinase
674
peroxidase
625
mitogen-activated protein kinase
492
CD13
402
P-glycoprotein
301
BMT
294
reverse transcriptase
284
topoisomerase
282
topoisomerase
250
caspase-3
199
DNA methyltransferase
182
protein kinase
176
CD10
169
MEK
158
lactate dehydrogenase
135
isocitrate dehydrogenase
131
isocitrate dehydrogenase
131
PARP
127
proteasome
121
RNA polymerase
120
luciferase
118
TdT
109
lysozyme
103
protein kinase C
93
alkaline phosphatase
91
asparaginase
86
transcriptase
70
caspase-8
70
phosphatidylinositol 3-kinase
67
MDR
66
caspase-9
62
demethylase
58
cdc2
50
DNA polymerase
50
deoxycytidine kinase
49
alanine aminotransferase
47
trypsin
45
histone acetyltransferase
45
calcineurin
44
more...
Compound
DNA
3152
Dec
2378
Clin
2005
retinoic acid
831
Ara-C
668
Ara-C
531
tyrosine
409
oxygen
368
THP
250
THP
250
ABL
239
BCR
236
lysine
208
acetate
195
MTT
186
benzene
179
VP-16
158
ATP
140
His
139
TNF
133
TBI
127
DFS
127
iron
126
serine
125
MEK
123
hydroxyglutarate
116
calcium
115
phosphate
110
sodium
109
5-Azacytidine
109
TEL
103
glucose
100
5-Aza-2'-deoxycytidine
97
iodine
97
arginine
93
CTP
89
leucine
78
cysteine
76
zinc
75
Adriamycin
74
more...