Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023380 (lethargy)
 5,697 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IBtk 10.4
intelectin 2 9.9
RNA binding motif protein 20 9.6
Kinesin light chain 9.4
goa 9.1
CACNB4 9.0
HMGCL 8.9
intrinsic factor-cobalamin receptor 8.9
3-hydroxy-3-methylglutaryl-CoA lyase 8.8
IER3IP1 8.7
CUBN 8.6
MICE 8.6
DNAJA4 8.5
mitochondrial 3-oxoacyl-CoA thiolase 8.5
PCCB 8.5
FLAD1 8.4
NDUFA5 8.4
SLC25A15 8.4
chaperonin containing t-complex polypeptide 1 8.4
Cacng2 8.4
HMGCS2 8.3
isovaleryl-CoA dehydrogenase 8.3
Medium-chain acyl-CoA dehydrogenase 8.3
TBX19 8.1
ATP5D 8.1
lysosomal acid beta-galactosidase 8.0
CML28 7.9
DHTKD1 7.9
N61 7.8
CD11d 7.8
CA5 7.7
CYP2F 7.6
PCCA 7.6
ABC-C 7.5
propionyl-CoA carboxylase 7.5
3-hydroxy-3-methylglutaryl CoA 7.5
infantile malignant osteopetrosis 7.4
N-acetylglutamate synthetase 7.4
HMG-CoA lyase 7.4
ACADM 7.4
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Disease
Bacterial aneurysm 12.4
Acquired hydrocephalus 12.4
Coryzal symptoms 12.4
Lobular dissecting hepatitis 12.4
Situs inversus abdominalis 11.4
Minor depressive disorder 11.4
Classical Maple Syrup Urine Disease 11.4
Chronic frontal sinusitis 11.4
Gallbladder infection 11.4
Hexamitiasis 11.4
Adenoviral pneumonia 10.9
naegleriasis 10.9
Intestinal strangulation 10.9
Metaphyseal osteopathy 10.9
Light chain myeloma 10.9
Irreversible renal failure 10.9
Familial nephropathy 10.9
Gallbladder mucocele 10.9
Beta-ketothiolase deficiency 10.6
Centrilobular hepatic necrosis 10.4
Cobalamin C disease 10.4
Acute dermatitis 10.1
Peripheral vestibular disease 10.1
Visceral gout 10.1
Intractable vomiting 10.1
protozoal meningoencephalitis 10.1
Pituitary infarction 10.1
Idiopathic intussusception 9.9
Chronic gastric volvulus 9.9
Endocardiosis 9.9
Gastroesophageal intussusception 9.9
Anterior communicating artery aneurysm 9.9
Lymphocytic-plasmacytic enteritis 9.6
C cell adenoma 9.6
growth hormone secreting adenoma 9.6
Intestinal lymphoma 9.6
Adrenal carcinoma 9.6
Regenerative anemia 9.6
Intracranial venous thrombosis 9.6
hyperglycinemia 9.5
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Symptom
lethargy 12.4
Multiple symptomatology 11.4
Bulging fontanelle 10.9
decreased skin turgor 10.3
abnormal urination 10.1
dysorexia 9.7
lipuria 9.6
Chills and fever 9.1
Brudzinski's sign 9.0
eye discharge 8.9
labored breathing 8.9
Kernig's sign 8.8
decreased appetite 8.6
prickling sensation 8.5
anorexia 8.4
cracked lips 8.3
Dribbling 8.2
Mucosal hyperplasia 8.2
Mental status changes 8.2
dry throat 8.1
emaciation 8.0
muscular incoordination 7.9
ketonuria 7.9
polydipsia 7.9
abnormal breathing 7.9
Soft stools 7.9
enanthema 7.7
Sore 7.6
tachypnea 7.6
abnormal taste 7.5
pallor 7.5
GI irritation 7.5
facial droop 7.5
prostration 7.4
Pain and tenderness 7.4
strangury 7.4
polyuria 7.3
adipsia 7.2
catatonia 7.1
asterixis 7.1
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Drug
Metacresol 11.4
Liskantin 11.4
Methyldopate 10.9
Elsamitrucin 10.9
Tribromomethane 10.9
Butamirate citrate 10.9
Fostedil 10.1
Loxapin 9.9
Cnidii rhizoma 9.7
Loxapine succinate 9.6
Rubitecan 9.4
Dirlotapide 9.4
Propoxyphene napsylate 9.4
Ilmofosine 8.7
Methsuximide 8.6
Selenium sulfide 8.6
Smallpox vaccine 8.1
Dantrium 8.1
Edatrexate 8.1
Bendrofluazide 8.1
Oxyphenbutazone 7.9
Deferoxamine mesylate 7.9
Artane 7.9
Remeron 7.9
Aldomet 7.8
Oxyphenbutazone 7.8
Cardura 7.7
Cardura 7.7
Alacepril 7.7
Digibind 7.5
Artane 7.4
Belladonna 7.4
Gadobenate dimeglumine 7.3
Pleconaril 7.1
Visken 7.0
Leukine 7.0
Pralidoxime 6.8
Triprolidine 6.8
Humalog 6.7
Stiripentol 6.7
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Enzyme
3-hydroxy-3-methylglutaryl-CoA lyase 8.5
isovaleryl-CoA dehydrogenase 8.5
4-nitrophenol hydroxylase 7.7
propionyl-CoA carboxylase 7.6
glycine N-acyltransferase 7.4
propionyl-CoA carboxylase 7.3
propionyl-CoA synthetase 7.3
biotinidase 6.8
methylmalonyl-CoA mutase 6.6
HMG-CoA synthase 6.1
thiamine pyrophosphokinase 5.8
acyl-CoA dehydrogenase 5.8
carbamoylphosphate synthetase 5.8
N-acetylglutamate synthase 5.7
EC 2.7.7.9 5.5
guanidinoacetate methyltransferase 5.3
tripeptidyl peptidase 5.3
N-acetylglutamate synthase 5.2
glycine decarboxylase 4.9
ornithine transcarbamylase 4.9
acyl-CoA dehydrogenase 4.8
glutaryl-CoA dehydrogenase 4.7
pyruvate carboxylase 4.7
4-hydroxyphenylpyruvate dioxygenase 4.6
fumarylacetoacetate hydrolase 4.3
succinic semialdehyde dehydrogenase 4.2
aspartate aminotransferase 4.2
acetoacetyl-CoA thiolase 4.1
3-hydroxyacyl-CoA dehydrogenase 4.1
argininosuccinate synthetase 4.0
alanine aminotransferase 4.0
sorbitol dehydrogenase 4.0
ACAT 3.9
lactate oxidase 3.9
lactic acid dehydrogenase 3.9
mannosidase II 3.8
creatine kinase 3.8
GABA transaminase 3.8
arginine kinase 3.7
lactic acid dehydrogenase 3.6
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Compound
Suberylglycine 12.4
1-bromo-2-fluoroethane 12.4
Juliflorine 11.4
2-Amino-5-nitrophenol 11.4
Ammelide 10.4
Ethyl methacrylate 10.4
2-Amino-4-nitrophenol 9.9
butanal oxime 9.6
Fenpyroximate 9.4
Naphthol AS-D 9.3
Tetrahydrozoline 9.3
Thaliblastine 9.1
Doxepin hydrochloride 8.7
Cyclobenzaprine 8.5
2-furaldehyde semicarbazone 8.4
Fludrocortisone acetate 8.4
Naphthol AS-D 8.4
Metaxalone 8.4
Quazepam 8.3
3-O-Methyldopa 8.3
Methacrylonitrile 8.3
p-Nitrobenzoic acid 8.2
Neomycin sulfate 8.2
Indocin 8.1
Neomycin sulfate 8.1
Aurin 7.9
Aminoglutethimide 7.9
C8H18 7.7
Lysergic acid 7.7
Hexachlorobutadiene 7.5
Chloranil 7.5
Nickel sulfate 7.4
Merbarone 7.4
Tiazofurin 7.4
MTIC 7.4
3-hydroxyisovaleric acid 7.3
2-methylcitric acid 7.3
Fostriecin 7.2
N,N'-diisopropylcarbodiimide 7.2
Sphinganine 7.2
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