Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023380 (lethargy)
 5,697 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 414
She 281
MRI 116
insulin 89
CSF 72
lymphoid 68
alkaline phosphatase 58
aspartate aminotransferase 57
hemoglobin 56
Mol 55
cytokine 43
Rec 41
alanine aminotransferase 39
lipopolysaccharide 39
vasopressin 36
interferon 33
fur 33
gut 32
parathyroid hormone 31
creatine kinase 31
thyroid hormone 30
albumin 29
B12 29
IL-6 28
thymus 26
beta-endorphin 24
cage 24
TNF 23
C-reactive protein 22
calcium channel 22
tumor necrosis factor 21
prothrombin 21
ACTH 21
GABA 20
IgE 19
vimentin 18
Polymerase 17
lactate dehydrogenase 17
glial fibrillary acidic protein 17
Gen 17
non-Hodgkin's lymphoma 16
growth hormone 15
ATP 15
thromboplastin 15
olfactory 15
Pseudomonas 14
glucagon 14
renin 14
cytokeratin 14
adrenocorticotropic hormone 14
interleukin-6 14
NTP 13
IFN 13
chronic renal failure 13
erythroid 13
white cell 12
X-linked 12
ornithine transcarbamylase 12
AST 12
osteosarcoma 12
fibrinogen 11
endoplasmic reticulum 11
MICE 11
LPS 11
prolactin 11
CD4 11
ferritin 11
parathyroid hormone-related protein 10
granulocyte 10
acetylcholinesterase 10
propionyl-CoA carboxylase 10
reserved 10
panhypopituitarism 10
calcitonin 10
carp 10
GSH 10
hole 10
San 9
CD20 9
erythropoietin 9
methylmalonyl-CoA mutase 9
CD79a 9
interferon-alpha 9
SARS 9
tap 9
serum protein 9
CO2 8
nodal 8
orexin 8
thyroid stimulating hormone 8
IL-10 8
S100 8
methemoglobin 8
CRP 8
hedgehog 8
lipase 8
biotinidase 8
serum albumin 8
axonal 8
AMP 8
catalase 8
polypeptide 7
renal amyloidosis 7
ALP 7
DBA 7
LDH 7
parathormone 7
desmin 7
interleukin-2 7
HLA 7
kit 7
collagen 7
IgA 7
PTH 6
Medium-chain acyl-CoA dehydrogenase 6
HMG-CoA synthase 6
serum amyloid A 6
synaptophysin 6
von Willebrand factor 6
REM 6
leptin 6
cytochrome 6
tumor necrosis factor alpha 6
carbamoylphosphate synthetase 6
amylase 6
IL-4 6
peroxidase 6
neuraminidase 6
myeloperoxidase 6
dilute 6
FDG 6
CD45 6
gag 6
TNF-alpha 5
RDX 5
esterase 5
HFE 5
somatostatin 5
ape 5
hemochromatosis 5
isovaleryl-CoA dehydrogenase 5
reductase 5
BID 5
IL-8 5
SNAP 5
pyruvate kinase 5
thyroglobulin 5
Walker 5
estrogen receptor 5
long chain 5
granulocyte colony-stimulating factor 5
transcobalamin II 5
CAT 5
NOD 5
HMGCS2 5
glutathione peroxidase 5
neuron-specific enolase 5
pyruvate carboxylase 5
Cav2.1 5
vascular endothelial growth factor 5
more...
Disease
coma 364
depression 352
anemia 339
tumor 274
cancer 243
confusion 211
dehydration 207
thrombocytopenia 187
sepsis 171
encephalopathy 158
hypoglycemia 142
sepsis 139
pneumonia 134
encephalitis 124
fits 123
hypertension 122
rash 107
epilepsy 105
meningitis 98
diabetes 93
lymphadenopathy 92
lymphoma 90
hypercalcemia 90
hypothyroidism 79
carcinoma 77
hydrocephalus 75
stroke 74
renal failure 73
infectious diseases 72
leukemia 72
hepatitis 72
influenza 70
neutropenia 69
metastases 65
virus infection 64
hemiparesis 62
azotemia 61
dermatitis 61
failure to thrive 60
psychosis 60
cold 59
renal disease 53
respiratory failure 53
leukopenia 52
disorientation 52
immunodeficiency 51
vasculitis 50
malnutrition 48
hyperglycemia 48
blindness 47
intussusception 45
Infection 44
adenoma 44
heart failure 44
cardiomyopathy 43
proteinuria 42
delirium 41
Mycoplasma 41
adenocarcinoma 41
myocarditis 41
lymphopenia 41
pruritus 40
Thoracic 40
subarachnoid hemorrhage 40
meningoencephalitis 39
autism 39
peritonitis 39
hemolytic anemia 39
pericardial effusion 38
HIV 38
AIDS 38
congestive heart failure 38
pulmonary edema 37
acute renal failure 37
enteritis 36
dysphagia 36
obesity 36
enterocolitis 35
pancytopenia 34
dementia 34
lactic acidosis 34
Mycobacterium 34
coagulopathy 34
developmental delay 34
hallucinations 32
endocarditis 32
status epilepticus 32
diabetic ketoacidosis 32
aggression 32
conjunctivitis 32
petechiae 31
tuberculosis 31
West 31
pancreatitis 31
hyperphagia 30
nystagmus 30
ischemia 30
liver disease 29
eosinophilia 28
mental retardation 28
mental retardation 28
bowel obstruction 28
breast cancer 27
gastroenteritis 27
bacteremia 26
schizophrenia 26
malabsorption 26
disseminated intravascular coagulation 26
lymphadenitis 26
herpes simplex 26
primary hyperparathyroidism 26
multiple myeloma 25
cirrhosis 25
parkinsonism 25
lymphocytosis 24
methylmalonic acidemia 24
interstitial pneumonia 24
hyperbilirubinemia 24
hypernatremia 24
respiratory disease 24
ketosis 24
incontinence 24
myopathy 23
toxoplasmosis 23
migraine 23
stomatitis 23
urinary tract infection 23
myelosuppression 22
bacterial infection 22
renal cell carcinoma 22
babesiosis 22
metabolic disorder 22
ehrlichiosis 22
hypercholesterolemia 22
bipolar disorder 22
hepatocellular carcinoma 22
hyperphosphatemia 22
acute lymphoblastic leukemia 21
aphasia 21
Alzheimer's disease 21
hyperparathyroidism 21
encephalomyelitis 21
cognitive impairment 21
adrenal insufficiency 21
Reye's syndrome 21
renal insufficiency 21
propionic acidemia 20
neurological disease 20
glomerulonephritis 20
hypercortisolism 20
diabetes insipidus 20
Autism 20
melanoma 20
tetraplegia 19
chronic renal failure 19
arthritis 19
bronchopneumonia 19
squamous cell carcinoma 19
prolapse 19
systemic lupus erythematosus 19
more...
Symptom
lethargy 5697
anorexia 844
vomiting 755
seizures 497
diarrhea 463
weakness 404
headache 352
fatigue 240
nausea 235
ataxia 232
pain 194
dyspnea 193
sleepiness 184
abdominal pain 160
hypotonia 136
cough 130
respiratory distress 112
dizziness 98
Ill 97
hepatomegaly 97
polydipsia 94
hypothermia 93
splenomegaly 93
tachypnea 90
agitation 88
polyuria 84
decreased appetite 83
pallor 83
constipation 79
anesthesia 69
cyanosis 55
myalgia 49
insomnia 48
tremor 48
nausea and vomiting 47
emaciation 47
collapse 40
arthralgia 39
paresis 35
apathy 35
hepatosplenomegaly 33
chills 33
colic 33
shortness of breath 31
chest pain 30
erythema 30
nasal discharge 29
cachexia 28
dysarthria 27
catatonia 27
regurgitation 27
ketonuria 24
discomfort 23
back pain 23
hypersomnia 22
discomfort 22
dystonia 21
tonic-clonic seizure 21
blurred vision 20
hypoproteinemia 19
incoordination 19
sore throat 18
labored breathing 18
syncope 18
vertigo 18
night sweats 17
hemiplegia 17
numbness 17
myoclonus 16
dry skin 16
paresthesia 15
spasticity 15
asthenia 14
analgesia 14
neck stiffness 13
sneezing 13
oliguria 12
cerebellar ataxia 12
dysuria 12
bone pain 12
abdominal discomfort 12
prostration 11
starvation 11
rhinorrhea 11
ophthalmoplegia 11
spasm 10
neck pain 10
memory loss 10
abnormal breathing 9
hemoptysis 9
forgetfulness 9
retching 9
exhaustion 9
wheezing 9
angina 9
bloating 8
fever of unknown origin 8
flushing 8
twitching 8
hunger 8
hypercapnia 8
consciousness disturbance 8
abnormal gait 8
torticollis 8
lightheadedness 8
excessive sweating 7
chronic cough 7
paraparesis 7
meningism 7
epigastric pain 7
overweight 7
rigors 6
hoarseness 6
blepharospasm 6
eye discharge 6
nasal congestion 6
tense 6
acute abdominal pain 5
rales 5
asterixis 5
hopelessness 5
snoring 5
adenitis 5
adipsia 5
hyperesthesia 5
photophobia 5
muscle cramps 5
limb pain 4
dark urine 4
loss of balance 4
bradykinesia 4
exertional dyspnea 4
facial droop 4
lassitude 4
stridor 4
drooling 4
pleuritic chest pain 4
anosmia 4
clumsiness 4
Sedation 4
hypertonia 4
chorea 4
personality change 4
fasciculation 4
Kernig's sign 4
physical appearance 4
acute abdomen 3
Physical findings 3
chest tightness 3
productive cough 3
loss of equilibrium 3
tinnitus 3
swollen joints 3
Depressive symptoms 3
Decreased activity 3
urinary frequency 3
dyschezia 3
hot flushes 3
ataxic gait 3
enuresis 3
more...
Drug
CSF 73
ampicillin 31
Dermatol 23
Cardiovasc 13
lysine 12
ascorbate 8
Vitamin B12 8
caffeine 8
Nephron 7
PTH 7
vitamin E 6
Ethanol 5
Spectrum 5
CTX 5
Spectrum 5
Sodium valproate 4
Gabapentin 4
DPA 4
Ringer's solution 4
Reserpine 4
lactose 4
Acyclovir 4
Asthma 4
Doxycycline 4
Tacrolimus 4
Sumatran 4
citric acid 4
Portal 4
ABC 4
Nephron 4
Clonidine 3
ENT 3
niacin 3
Itraconazole 3
Swainsonine 3
Cobalamin 3
Adriamycin 3
IFN-gamma 3
Leaf 3
Mirtazapine 3
TTC 3
Gel 3
Kenyan 3
G-CSF 3
Monit 3
IL-2 3
PCP 3
CTX 2
CTC 2
EE2 2
NADH 2
Salicylate 2
Magnesium sulfate 2
Digibind 2
Modafinil 2
Photofrin 2
Phenytoin 2
Trental 2
Captopril 2
MAP 2
DDAVP 2
CPR 2
Metrizamide 2
Dial 2
Bayer 2
Cimetidine 2
CTC 2
DDAVP 2
Serum albumin 2
Dextrose 2
Cremophor EL 2
Cnidii rhizoma 2
Cimetidine 2
OTC 2
Prednisolone 2
Fluconazole 2
Prednisone 2
THF 2
Triazolam 2
FAD 2
CTX 2
Amoxicillin 2
Methylprednisolone 2
Diphenhydramine 2
Sucralfate 2
Methyldopa 2
Isoniazid 2
Vitamin B 2
Bendrofluazide 1
Keppra 1
Posture 1
Butamirate citrate 1
Visken 1
Trimethoprim-sulfamethoxazole 1
Escitalopram 1
Carbenoxolone 1
Parlodel 1
TiO2 1
PCB 1
Trilostane 1
Parkin 1
Leucovorin 1
CCL 1
Riboflavin 1
DMAP 1
Bupivacaine 1
CTA 1
Meropenem 1
Oxyphenbutazone 1
Hydrochlorothiazide 1
Cardura 1
Liraglutide 1
Dexrazoxane 1
Mesalazine 1
Artesunate 1
Parkin 1
Artane 1
metformin hydrochloride 1
Sodium benzoate 1
Dextropropoxyphene 1
HPMPC 1
Alacepril 1
Prozac 1
Liskantin 1
Methyldopate 1
Atomoxetine 1
Loxapine succinate 1
nitroglycerin 1
Hyperforin 1
ACT 1
ARA-C 1
Viagra 1
MRC 1
Viagra 1
Parlodel 1
Vitamin K 1
Fenbendazole 1
Vinorelbine 1
Fostedil 1
Dirlotapide 1
Coral 1
Epoetin alfa 1
Domperidone 1
Imatinib 1
Atropine 1
Casodex 1
Check 1
FCV 1
Valproic Acid 1
Sandostatin 1
Aldomet 1
Nitric Oxide 1
Dantrolene sodium 1
Norplant 1
Limonene 1
Stiripentol 1
Intron A 1
Oseltamivir 1
Codeine 1
TAT 1
more...
Enzyme
alanine aminotransferase 76
aspartate aminotransferase 71
alkaline phosphatase 58
creatine kinase 47
lactate dehydrogenase 23
thromboplastin 16
acyl-CoA dehydrogenase 14
acetylcholinesterase 14
renin 14
catalase 13
gamma-glutamyl transpeptidase 13
propionyl-CoA carboxylase 12
AST 12
peroxidase 12
reverse transcriptase 11
propionyl-CoA carboxylase 10
ERK 9
ornithine transcarbamylase 9
cholinesterase 9
lipase 8
biotinidase 8
cytochrome oxidase 8
RNA polymerase 8
pyruvate carboxylase 7
monoamine oxidase 7
trypsin 7
methylmalonyl-CoA mutase 7
ATPase 7
transcriptase 6
neuraminidase 6
focal adhesion kinase 6
isovaleryl-CoA dehydrogenase 6
HMG-CoA synthase 6
superoxide dismutase 5
APC 5
glutathione peroxidase 5
urease 5
3-hydroxy-3-methylglutaryl-CoA lyase 5
pyruvate kinase 5
mitogen-activated protein kinase 5
urease 5
urokinase-type plasminogen activator 4
acyl-CoA dehydrogenase 4
DNA polymerase 4
complex I 4
lysozyme 4
ACE 4
calcineurin 4
acid phosphatase 4
botulinum neurotoxin 4
alcohol dehydrogenase 4
CPT 4
thrombin 3
tissue plasminogen activator 3
glycine decarboxylase 3
thymidylate synthase 3
tryptophan hydroxylase 3
ATP synthase 3
asparaginase 3
carbamoylphosphate synthetase 3
sorbitol dehydrogenase 3
thymidine kinase 3
tyrosine hydroxylase 3
beta-lactamase 3
pyruvate dehydrogenase 3
PCP 3
sulfatase 3
glucose-6-phosphatase 3
protein kinase 3
hyaluronidase 3
hyaluronidase 3
carboxylesterase 3
diaphorase 3
P-glycoprotein 3
glucose-6-phosphate dehydrogenase 3
glutamate decarboxylase 2
glutathione reductase 2
aldolase 2
beta-glucuronidase 2
granzyme B 2
chymotrypsin 2
CPT 2
carbonic anhydrase 2
plasmin 2
prostate-specific antigen 2
succinate dehydrogenase 2
argininosuccinate synthetase 2
alpha-mannosidase 2
enolase 2
adenylate kinase 2
CPR 2
CPT 2
phosphofructokinase 2
proteasome 2
lactic acid dehydrogenase 2
phospholipase A2 2
3-hydroxyacyl-CoA dehydrogenase 2
transpeptidase 2
CD10 2
citrate synthase 2
thyroid peroxidase 2
GABA transaminase 2
NADH dehydrogenase 2
ADH 2
phosphoglucomutase 2
caspase-3 2
EC 2.7.7.9 1
firefly luciferase 1
LasR 1
FAST 1
cholesterol acyltransferase 1
methionine synthase 1
N-acetylglutamate synthase 1
RNase 1
ACAT 1
glycerol kinase 1
methylenetetrahydrofolate reductase 1
alpha-glucosidase 1
ACS 1
lactic acid dehydrogenase 1
dihydropyrimidine dehydrogenase 1
NADH-cytochrome b5 reductase 1
methylenetetrahydrofolate reductase 1
protein phosphatase 2A 1
arginase 1
pepsin 1
TPP 1
choline acetyltransferase 1
NQO1 1
endonuclease 1
HSD 1
demethylase 1
transketolase 1
arginine kinase 1
Alternating 1
SPC 1
4-hydroxyphenylpyruvate dioxygenase 1
phosphodiesterase 1
N-acetylglutamate synthase 1
propionyl-CoA synthetase 1
PAH 1
dihydropyrimidine dehydrogenase 1
TAT 1
hormone-sensitive lipase 1
MDP 1
glyceraldehyde-3-phosphate dehydrogenase 1
adenosine deaminase 1
acetyl-CoA carboxylase 1
BMT 1
pyruvate dehydrogenase 1
thiamine pyrophosphokinase 1
guanidinoacetate methyltransferase 1
glutaryl-CoA dehydrogenase 1
glycine N-acyltransferase 1
adenosine deaminase 1
MDR 1
glutamate synthase 1
AMP deaminase 1
arylsulfatase A 1
glutamate synthase 1
more...
Compound
Clin 424
Dec 414
water 215
sodium 180
DNA 157
calcium 154
glucose 154
His 102
urea 102
creatinine 83
oxygen 82
potassium 69
ammonia 67
A 3 65
nitrogen 56
zinc 54
iron 51
salt 44
phosphate 32
phosphorus 32
Cardiol 31
acetate 29
arginine 29
ethanol 28
vitamin D 28
CO2 24
barium 24
TNF 23
copper 23
aldosterone 23
A 1 22
ACTH 21
CoA 21
sulfate 21
GABA 20
galactose 20
Thyroid 20
leucine 20
GABA 20
glutamate 19
carbonate 19
tyrosine 18
ammonium 17
Valproic acid 17
noradrenaline 16
hydrogen 16
L-carnitine 16
ATP 15
TSH 15
glutamine 14
PEG 14
alanine 13
PEG 13
lysine 13
tryptophan 12
5-HT 12
tryptophan 12
tryptophan 12
Ile 12
tryptophan 12
GSH 11
GSH 11
isoleucine 10
isoleucine 10
methionine 10
DSM 10
homocysteine 10
silver 10
sodium chloride 10
hydroxide 9
Diazepam 9
cyanide 9
Isoproterenol 9
Aminoglutethimide 9
selenium 9
caffeine 8
Guo 8
ornithine 8
Thyroxine 8
Primatol 8
ornithine 8
ornithine 8
Guo 8
ornithine 8
Primatol 8
Primatol 8
AMP 8
ornithine 8
Insulin 8
acetone 8
bromide 7
ALP 7
cysteine 7
nitrate 7
DBA 7
glutamic acid 7
PAS 7
DBA 7
methanol 7
EDTA 7
Lithium 7
oxalate 7
DBA 7
Mg2+ 7
nitric oxide 7
valine 7
Naloxone 7
A 71 6
Valproic acid 6
iodine 6
N-acetylcysteine 6
gamma-aminobutyric acid 6
L-DOPA 6
mercury 6
Lead 6
Neuronal 6
Dexamethasone 6
EDTA 6
NH2 6
threonine 6
chlorine 6
propionic acid 5
NIDA 5
Levetiracetam 5
6-12 5
CAT 5
nicotinamide 5
hydroxyindoleacetic acid 5
CAT 5
serine 5
cobalt 5
salicylic acid 5
Off 5
Phe 5
ASA 5
Topiramate 5
CAT 5
Neo 5
CTX 5
DTPA 5
RDX 5
propionic acid 5
phosphocreatine 5
manganese 5
Hemoglobin 5
Adriamycin 5
3-hydroxyisovaleric acid 5
aluminum 5
Congo red 5
Retinal 4
Doxycycline 4
DSS 4
TEM 4
APAP 4
HMG-CoA 4
1,3,5-triazine 4
folinic acid 4
Adrenal 4
Sodium 4
alcohol dehydrogenase 4
more...