Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0023380 (
lethargy
)
5,697
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Theophylline
toxicity developed within 48 hours of admission in a 63-year-old alcoholic male who presented with shortness of breath, edema, and
lethargy
. Using liquid chromatography, a serum theophylline half-life of 134 hours was observed following discontinuation of the drug. This report emphasizes the effect of hepatic disease on theophylline clearance and the need for frequent monitoring of plasma theophylline concentrations in cirrhotic patients.
...
PMID:Markedly prolonged theophylline half-life in liver failure. 709 49
