Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023380 (lethargy)
 5,697 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A cross sectional survey investigating "building sickness" was carried out in two buildings with similar populations of office workers but differing ventilation systems, one being fully air conditioned with humidification and the other naturally ventilated. The prevalence of symptoms related to work was assessed by a questionnaire administered by a doctor. A stratified, randomly selected sample of workers was seen (84% response). Building sickness includes several distinct syndromes related to work, most of which were significantly more common in the air conditioned building than the naturally ventilated building--namely, rhinitis (28% v 5%), nasal blockage and dry throat (35% v 9%), lethargy (36% v 13%), and headache (31% v 15%). The prevalence of work related asthma and humidifier fever was low and did not differ significantly between the two buildings. An environmental assessment of the offices was performed to attempt to identify possible factors responsible for the differences in the prevalence of disease. Globe temperature, dry bulb temperature, relative humidity, moisture content, air velocity, positive and negative ions, and carbon monoxide, ozone, and formaldehyde concentrations were all measured. None of these factors differed between the buildings, suggesting that building sickness is caused by other factors.
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PMID:Comparison of health problems related to work and environmental measurements in two office buildings with different ventilation systems. 392 99

Self-administered questionnaires were used to find out the prevalence among employees working in the three local authority premises in a Health District of self-reported illness which could be associated with sick building syndrome. Eye symptoms were found to be more common among employees working in a typing centre using VDUs. The symptoms tiredness, lethargy and influenza-like ('flu-like) illness, including aches in the limbs, were reported in significantly higher numbers by employees working in areas where there was evidence of increased pressure of work and worries over job losses. Dry throat and blocked or stuffy nose were symptoms reported in significantly higher proportions by employees working in certain buildings, where anecdotal evidence suggested that there could be problems with temperature regulation. This study also confirmed findings by other studies that for some symptoms women complain in significantly higher numbers than men. It was concluded that the type of work people do, in addition to the type of building they work in, play an important role in self-reported illnesses. Causation of sick building syndrome is complex and probably of multifactorial origin.
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PMID:An investigation into sick building syndrome among local authority employees. 797 93