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Query: UMLS:C0023380 (lethargy)
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Yersinia pseudotuberculosis infection in the cat is described. Clinical findings included inappetence, lethargy, rapid emaciation, jaundice and an enlarged left kidney. Chronic pseudotubercular lesions were found in the kidneys and lungs and Yersinia pseudotuberculosis Type IIB was recovered from both sites.
Vet Rec 1977 May 14
PMID:Yersinia pseudotuberculosis in the cat. 32 72

An acute respiratory distress syndrome in 10 adult dogs was usually preceded by vomiting, anorexia and lethargy followed, after a short interval, by dyspnoea. The dyspnoea became increasingly severe, despite oxygen therapy, and cyanotic respiratory failure ensued. All 10 dogs died or were killed after illnesses lasting between one and eight days. Necropsies revealed pulmonary congestion, oedema, collapse and haemorrhage with loss of alveolar epithelial cells. Early alveolar fibrosis was also found. Paraquat was identified in post mortem samples from four of the 10 dogs.
Vet Rec 1977 Apr 02
PMID:Acute respiratory distress in the dog associated with paraquat poisoning. 86 Mar 82

The clinical syndrome of a new disease of pigs in four herds in the Humberside area is described. The first signs of the disease were anorexia, lethargy and pyrexia with up to 60 per cent of the dry sows affected. These signs were followed by an increased incidence of abortions which occurred in up to 3.3 per cent of sows, premature farrowings in up to 20.6 per cent of sows and stillbirths and late mummification which affected up to 26.0 and 18.8 per cent of fetuses, respectively. Mortality in neonatal and pre-weaning pigs reached up to 88 per cent and respiratory disease of high morbidity and low mortality occurred in fattening pigs. There were infertility problems in sows, with an increase in returns to service and a failure to show oestrus after weaning or aborting. The signs of the disease in boars were anorexia and malaise. Cyanosis of the extremities affected up to 2 per cent of the animals. The outbreak lasted 11 weeks in all the herds.
Vet Rec 1992 Aug 15
PMID:An outbreak of blue-eared pig disease (porcine reproductive and respiratory syndrome) in four pig herds in Great Britain. 141 21

In September 1991 cataracts occurred in two year-classes of triploid Atlantic salmon. The fish showed varying degrees of blindness, were lethargic and became emaciated owing to their inability to feed. The lesions in the lens were mainly in the anterior and posterior cortex and perinuclear areas, the capsule and embryonic nucleus remaining unaffected. Diploid fish of the same year-class did not have cataracts. The origin of the triploid fish, the method of triploidisation, their diet and disease status were investigated, but no predisposing factors could be found to account for the high incidence of cataracts.
Vet Rec 1992 Dec 12
PMID:Occurrence of cataracts in triploid Atlantic salmon (Salmo salar) on four farms in Scotland. 148 45

Clinical examination of a four-and-a-half-month old foal revealed evidence of progressive heart failure associated with an atrial septal defect and atrial fibrillation. Atrial septal defects are rarely reported in foals and the foal's growth, development and demeanour were normal until a sudden onset of lethargic behaviour. The value of B-mode echocardiography in identifying the congenital lesion is indicated.
Vet Rec 1991 Jan 26
PMID:Atrial septal defect and atrial fibrillation in a foal. 201 53

Thoracic radiographs demonstrated a needle-like foreign body within the myocardium of a three-year-old male labrador retriever examined for an unrelated illness. Six months later the dog became lethargic and inappetent. The original foreign body had not moved, and a second needle was present in the stomach. Laparotomy and gastrotomy revealed a sewing needle which had perforated the lesser curvature of the stomach and was migrating cranially. An organised fibrous band extended through the diaphragm, and it is suspected that the original myocardial foreign body had migrated from the stomach by this route.
Vet Rec 1991 Apr 06
PMID:Suspected cranial migration of two sewing needles from the stomach of a dog. 206 25

Clinical hexamitiasis was recorded in pheasant poults between six and 12 weeks old, after placing the birds into release pens, and was characterised by reduced appetite, lethargy and emaciation. Post mortem the carcases were dehydrated. The presence in the lumen of the gut of characteristic motile organisms which could often be found several hours after death, provided a good clinical diagnosis. An emaciation syndrome, clinically similar but not associated with hexamitiasis or other pathogens also occurs in poults. It is characterised by extreme emaciation, largely confined to the pectoral muscles, and dehydration although the birds continue to eat and drink; the cause is unknown. Both hexamitiasis and the emaciation syndrome can cause high morbidity and mortality.
Vet Rec 1990 Mar 17
PMID:Hexamitiasis and an emaciation syndrome in pheasant poults: clinical aspects and differential diagnosis. 232 46

Thirty-two cats referred to the Feline Studies Centre between June 1987 and October 1988, and 14 in-contact cats, were found to be infected with feline immunodeficiency virus. Most of the 46 cats were non-pedigree and free ranging; 27 were male (19 neutered) and 19 were female (18 neutered). Their ages ranged from one to 17 years and the average age was 5.8 years. The most common clinical signs were lethargy, inappetence, weight loss, pyrexia and lymphadenopathy; most cases had multiple abnormalities. Other common signs were gingivitis, diarrhoea, rhinitis and ocular discharge. Eight cats had neoplasia. The commonest haematological abnormalities were anaemia, neutropenia, lymphopenia and monocytosis. Eight cats had lymphocytosis; seven of these were in a single house-hold. Several cats had high serum globulin levels and half of those tested had high IgG levels. Seven cats had no detectable antibody to feline immunodeficiency virus even though the virus was cultured from the peripheral blood lymphocytes. During follow-up for up to 60 weeks one cat died and 23 were destroyed on humane grounds.
Vet Rec 1989 Sep 23
PMID:Clinical and laboratory findings in cats infected with feline immunodeficiency virus. 255 57

Ten bitches with urinary incontinence due to incompetence of the urethral sphincter mechanism were treated with phenylpropanolamine hydrochloride at a dose of either 1 mg/kg orally three times daily or 2 mg/kg orally once daily in a prolonged release formulation. The signs of incontinence resolved in all the bitches, and improvements were maintained over periods ranging from one to more than two years, except in one bitch which became refractory to treatment after three months. One bitch which was inadvertently treated at a dose rate of 2.5 mg/kg showed signs of lethargy and inappetence but returned to normal when the dose rate was reduced.
Vet Rec 1989 Nov 04
PMID:Phenylpropanolamine: an alpha-adrenergic agent for the management of urinary incontinence in the bitch associated with urethral sphincter mechanism incompetence. 259 66

A four-year-old castrated male domestic shorthair cat with recent onset of lethargy and depression was found to have hypokalaemia, low plasma bicarbonate concentration and a urine pH of 7. Subsequent findings of hyperchloraemic metabolic acidosis with failure to produce acid urine led to a diagnosis of distal renal tubular acidosis. Pyelonephritis associated with Escherichia coli infection of the urinary tract was also diagnosed. The urinary tract infection was eliminated by antibiotic treatment. For two years subsequently, the clinical effects of distal renal tubular acidosis have been controlled by oral administration of potassium bicarbonate, although some biochemical abnormalities have persisted.
Vet Rec 1986 Jul 19
PMID:Distal renal tubular acidosis in a cat with pyelonephritis. 352 97


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