Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0023241 (Legionella)
 6,990 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The possibility of indigenous Legionnaires' disease should be known as suggested by the following case : a 69-year-old man, diabetic, having never travelled out of Poitou, suffers from serious pneumonia with dyspnea needing mechanical ventilation with positive end-expiratory pressure. After failure of ampicillin, the evolution seems favourable with cotrimoxazole. However the discontinuation of this last drug is followed by a relapse which is treated with success by erythromycin. Serodiagnoses will be positive for Legionella Pneumophila serogroup I. This case, typical by its clinical features, makes itself noticed by its epidemiology and the relapse under cotrimoxazole, proving that erythromycin remains the choice antibiotic for these infections.
Sem Hop
PMID:[Acute respiratory distress syndrome: indigenous Legionnaires' disease (author's transl)]. 626 96