Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0023241 (
Legionella
)
6,990
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
With 28 beta-lactam antibiotics the susceptibilities of 60 strains of
Legionella
spp. (49
Legionella
pneumophila and 11 ATCC type strains of other
Legionella
species) were determined. Agar dilution testing was used on buffered charcoal-yeast extract agar to which 0.1% alpha-ketoglutarate was added. The most active of the penicillins tested were ampicillin (MIC = 0.06-8 mg/l) and temocilin (MIC = 0.125 - 16 mg/l); the most active cephalosporins were ceftazidime (MIC = 0.03 - 0.5 mg/l),
HR 810
(MIC = 0.06 - 1 mg/l) and cefoxitin (MIC = 0.125 - 2 mg/l). Of all the drugs tested imipenem had the most pronounced activity (MIC = .0075 - 0.06 mg/l).
...
PMID:Susceptibility of Legionella spp. to imipenem and 27 other beta-lactam antibiotics. 659 34
