Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0023241 (
Legionella
)
6,990
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Legionella
pneumophila was unable to grow in a chemically defined medium without arginine because it could not carry out the first step in the biosynthetic pathway, the conversion of glutamate to N-acetylglutamate. All strains examined could grow when N-acetylglutamate (or other later arginine precursors) were substituted for arginine. No activity corresponding to
N-acetylglutamate synthetase
could be detected in cell extracts of L. pneumophila.
...
PMID:Arginine biosynthesis in Legionella pneumophila: absence of N-acetylglutamate synthetase. 665 83
