Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0023241 (Legionella)
6,990 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Copper-silver ionisation is gaining popularity worldwide as a water disinfection method. We review the literature that supports the effectiveness and safety of the copper-silver ionisation pertaining to legionella control in water distribution systems. A search between January 1997 and January 2007 was conducted in relevant health databases: Medline, Embase, NHS CRD, Cochrane Library Plus, Web of Knowledge, IME (Spanish Medical Index) and IBECS (Health Sciences Bibliographic Index). Ten published studies were selected according to inclusion and exclusion criteria previously established; most of these were experimental. Legionella levels decrease with the application of any of the procedures used in these studies and the procedures can be combined to obtain better outcomes. No studies containing an economic evaluation were found. We conclude that copper-silver ionisation is an effective method to control legionella, bearing in mind that eradication cannot be achieved by any method in isolation. Maintaining high temperatures in the water system can maximise effectiveness of the method. Copper-silver appears to be safe, as long as ion levels are monitored and kept within international recommended levels. More studies with concurrent control group, long follow-up and economic evaluation are required to properly assess this procedure.
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PMID:Is copper-silver ionisation safe and effective in controlling legionella? 1790 90

Stuart Watkin BEng (Hons) MSc CEng MIHEEM, head of Engineering Compliance & Energy at North Tees & Hartlepool NHS Foundation Trust, reports on a recent six-month trial, at the Trust's University Hospital of North Tees, of a new saline-based disinfection system for combating Legionella. The system, from Danish company, DCW, has reportedly proven highly effective in keeping the water system at the test site, the hospital's North Wing, Legionella-free, impressing both estates and facilities/engineering personnel, and an independent consultant, with both its efficacy and lack of "side-effects".
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PMID:Legionella eliminated with no 'side-effects'. 2236 80

Susan Pearson BSc, a freelance journalist and communications consultant specialising in medicine and the environment (see also HEJ - April 2013), reports on discussions, at a recent educational seminar, on a pilot project undertaken by the Environmental Microbiology Unit at the Brighton and Sussex University Hospitals (BSUH) NHS Trust, which compared the effectiveness and accuracy of conventional 'culture' testing for Legionella in water systems, with a new, 'less labour-intensive', DNA-based testing system that can produce results 'in a matter of hours'.
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PMID:Pilot project for rapid Legionella testing. 2400 May 45

In June 2014 Public Health England confirmed a case of Legionnaires' disease (LD) in a neonate following birth at home in a hired birthing pool incorporating a heater and a recirculation pump which had been filled in advance of labour. The case triggered a public health investigation and a microbiological survey of an additional ten heated birthing pools hired or recently hired to the general public across England. The birthing pool used by the parent of the confirmed case was identified as the source of the neonate's infection following detection of Legionella pneumophila ST48 in both patient and environmental samples. Legionella species were detected by quantitative polymerase chain reaction but not culture in a further three pools together with other opportunistic pathogens identified by culture and matrix-assisted laser desorption ionization-time of flight (MALDI-ToF) mass spectrometry. A Patient Safety Alert from NHS England and Public Health England was issued stating that heated birthing pools filled in advance of labour should not be used for home births. This recommendation remains in place. This investigation in conjunction with other recent reports has highlighted a lack of awareness regarding the microbiological safety of heated birthing pools and their potential to be a source of LD and other opportunistic infections. Furthermore, the investigation raised important considerations with regards to microbiological sampling and testing in such incidents. Public health authorities and clinicians should consider LD in the differential diagnosis of severe respiratory infection in neonates within 14 days of a water birth.
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PMID:Heated birthing pools as a source of Legionnaires' disease. 2628 65

Speaking at a Legionella Control Association Open Day on 9 October last year in Tamworth, Mike Quest, an LCA director and Committee Member who is an independent water hygiene and safety consultant and an NHS Authorising Engineer, presented his standpoint on effective risk assessment and monitoring of complex hot and cold water systems. He also focused on some of the challenges for engineering and estates teams in maintaining water temperatures within 'safe limits' in modern buildings, with reference to the complications he had seen in a hospital project he has recently been working on.
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PMID:Hot and cold water issues deftly described. 2701 60

'Efficient productivity through innovation' was the theme of the first ever Hospital Innovations conference and exhibition at Olympia, London in late April. At the two-day event--supported by organisations including IHEEM, the Legionella Control Association, the Water Management Society, the BRE, and a sizeable number of English NHS Trusts--the Day Two keynote address by Lord Carter very much reflected this theme. Following his address at Healthcare Estates 2015, the Labour Peer focused further in London on his team's recent review of the 'productivity and efficiency' of English NHS Trusts, and explained how the initiative would progress in coming months. One of his key conclusions was that while the NHS consistently rates as one of the world's most efficient public health systems, innovation and good practice are rarely sufficiently shared or widely replicated service-wide, resulting in a considerable 'gap' between the best and worst-performing Trusts. HEJ editor, Jonathan Baillie, reports.
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PMID:Best practice not being sufficiently replicated. 2949 13