Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022716 (Menkes)
 1,057 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
NSFL1 14.9
ATP7A protein 14.2
MNK 13.9
golgin, RAB6-interacting 13.9
ATP7A 13.9
MNK2 13.7
lipocalin-interacting membrane receptor 13.3
PGAM3 13.3
AP1B1 13.3
WND 13.2
MNK1 12.7
ATOX1 12.6
Copper-transporting ATPase 12.6
Ras and Rab interactor 2 12.3
COX19 12.1
ATPase 7B 12.1
EIF4F 12.1
IBM2 12.1
MC1 12.0
CTL3 11.9
cation transporting ATPase 11.7
ATP7B 11.7
COG7 11.6
Wilson disease 11.6
AP19 11.1
hCTR2 11.1
sterolin 11.0
IGF2AS 10.9
COMMD1 10.8
copper transport protein 10.8
procollagen I N-proteinase 10.8
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10.8
nexilin 10.6
GNE 10.5
MURR1 10.5
N-acetylmannosamine kinase 10.5
TAL-H 10.5
Amine oxidase 10.4
X-linked recessive 10.3
Glutaredoxin-1 10.3
GORAB 10.2
Mnk2 10.2
hSVCT1 10.2
RPS25 10.1
duodenal cytochrome b 10.0
gastrokine 1 10.0
COX17 10.0
COX11 10.0
GEFH1 10.0
UDP-N-acetylglucosamine 2-epimerase 9.9
Sprouty 2 9.8
MLPH 9.8
ATP6V0A2 9.8
ATP7B protein 9.7
XNP 9.7
SLC16A2 9.7
APLP 9.7
KHS 9.6
GEF1 9.6
ST8SIA4 9.6
copper transporter 1 9.5
SCO1 9.5
Mnk1 9.5
ST8SIA2 9.5
PYCR1 9.5
VPS26 9.4
ARP1 9.4
ceruloplasmin 9.4
crinkled 9.4
CMP-sialic acid transporter 9.3
Lipin-1 9.2
PGK1 9.2
hephaestin 9.2
PRK2 9.1
EDS VI 9.1
P5C 9.1
PTB-associated splicing factor 9.0
MYO5A 9.0
SCO2 9.0
eukaryotic translation initiation factor 4E 9.0
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Disease
SMAX3 14.9
Hair disease 14.9
Ehlers-Danlos syndrome type IX 14.9
EDS VIIB 14.9
Menkes 14.9
disorders of copper metabolism 13.8
Pili torti 13.2
Swayback 12.9
Pollitt syndrome 12.9
Disorders of pigmentation 12.9
trichoptilosis 11.9
Sliding hiatal hernia 11.9
PARK5 11.6
Bladder diverticula 11.5
Trichorrhexis nodosa 11.3
QSM 11.3
cerebral degeneration 11.2
Cytotoxic edema 11.1
trichorrhexis 10.3
Copper deficiency 10.1
OHS 10.0
Ehlers-Danlos syndrome type VII 10.0
Aortic root dilatation 10.0
Wilson's disease 9.9
Kennedy syndrome 9.6
acrodermatitis enteropathica 9.6
sialic acid storage disease 9.6
cutis laxa 9.3
EDS IV 9.3
Gastric polyps 9.3
lipoprotein disorder 9.2
EDS VI 9.0
battered child syndrome 9.0
ARP1 8.7
pediatric disorder 8.7
disorders of amino acid metabolism 8.6
Bazex syndrome 8.6
Pelizaeus-Merzbacher 8.6
Netherton syndrome 8.5
CRD1 8.5
Angiodysplasia 8.0
glutaric aciduria 8.0
Ehlers-Danlos syndrome 7.9
incontinentia pigmenti 7.9
CPX 7.9
profound mental retardation 7.8
hemiplegic migraine 7.7
Griscelli syndrome 7.6
Herlitz 7.6
staghorn calculus 7.6
mitochondrial encephalomyopathy 7.4
Alpers 7.4
hypomelanosis of Ito 7.4
trichothiodystrophy 7.4
Kugelberg-Welander 7.3
osteochondrodysplasia 7.3
sideroblastic anemia 7.3
Norrie disease 7.2
FDH 7.2
aminoaciduria 7.2
MERRF 7.2
psychomotor impairment 7.2
Kearns-Sayre syndrome 7.1
angioid streaks 7.1
Scheie 7.1
Hermansky-Pudlak syndrome 7.1
Dubin-Johnson syndrome 7.1
scurvy 7.0
MELAS 7.0
Hallervorden-Spatz disease 6.9
arachnodactyly 6.9
Barth syndrome 6.9
pseudoxanthoma elasticum 6.9
OPS 6.9
PBT 6.9
failure to thrive 6.8
Zinc deficiency 6.7
choreoathetosis 6.7
MELAS 6.7
Leigh syndrome 6.7
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Symptom
Blotchy 10.9
Kayser-Fleischer ring 8.7
tonic seizure 7.2
hypotonia 7.0
athetosis 6.8
emaciation 6.8
dysarthria 6.0
clumsiness 5.8
partial seizure 5.5
dystonia 5.4
blepharospasm 4.9
ataxia 4.7
cerebellar ataxia 4.6
Neuropathic pain 4.4
myoclonus 4.4
seizures 4.3
ophthalmoplegia 4.2
hypothermia 3.8
paraparesis 3.5
lethargy 3.4
tremor 3.3
spasticity 3.2
hepatomegaly 2.4
paresis 2.4
splenomegaly 1.6
weakness 0.7
cough 0.3
starvation 0.3
anesthesia 0.1
dyspnea 0.1
diarrhea 0.1
vomiting -0.1
headache -0.9
pain -1.1
Drug
Satraplatin 10.1
Zinc acetate 9.3
Leucovorin 5.9
Orphan 5.8
CPT-11 5.0
Arsenic trioxide 4.6
ADR 3.9
Dakar 3.8
pyridoxal phosphate 3.6
Retinoic acid 3.1
HCH 3.1
Asn 2.9
Albumin 2.6
MAP 2.5
NADH 2.0
ascorbate 2.0
ABC 1.8
Nephron 1.8
lysine 1.4
Nephron 1.3
Dermatol 1.1
IL-2 1.0
CSF 1.0
vitamin E 0.8
Leaf 0.5
Cardiovasc -2.7
Enzyme
N-acetylmannosamine kinase 11.1
AtHMA4 10.4
UDP-N-acetylglucosamine 2-epimerase 10.2
N-acetylglucosamine kinase 9.6
N-acetylglucosamine 2-epimerase 9.6
ceruloplasmin 9.2
lysyl oxidase 9.1
CCS1 8.5
CCS 8.5
sulfhydryl oxidase 7.0
lysyl hydroxylase 6.9
CNPase 6.8
dopamine beta-hydroxylase 6.7
ATPase 6.6
type III procollagen 6.4
PAM 6.3
mannosidase II 6.3
biotinidase 6.3
transaldolase 6.2
cytochrome oxidase 6.2
sulfite oxidase 6.1
sulfite oxidase 6.0
argininosuccinate synthetase 5.5
PGM 5.4
ascorbate oxidase 5.3
tyrosinase 5.2
phenol oxidase 5.1
ALDH 5.1
prolyl hydroxylase 5.1
calcium pump 4.9
ECH 4.8
phosphoglycerate kinase 4.8
uricase 4.6
Thy1 4.6
diamine oxidase 4.6
dihydropyrimidine dehydrogenase 4.6
heme oxygenase 4.4
phenylalanine hydroxylase 4.4
gamma-glutamylcysteine synthetase 4.4
Mg2+-ATPase 4.3
chalcone synthase 4.3
sialyltransferase 4.3
sialyltransferase 4.3
sialyltransferase 4.3
endoglycosidase H 4.0
MEKK1 4.0
diaphorase 3.9
NADH dehydrogenase 3.8
hormone-sensitive lipase 3.8
complex I 3.8
superoxide dismutase 3.7
MAP 3.6
CPR 3.5
monoamine oxidase 3.5
mitogen-activated protein kinase 3.4
transcriptase 3.3
succinate dehydrogenase 2.9
MMP 2.8
PAH 2.8
chloramphenicol acetyltransferase 2.6
pyruvate kinase 2.5
hexokinase 2.5
pyruvate dehydrogenase 2.5
MEK 2.3
ribonuclease 2.2
ribonuclease 2.2
GSK 2.2
prostate-specific antigen 2.1
lipoprotein lipase 2.1
tyrosine hydroxylase 2.0
ERK 1.8
RNA polymerase 1.8
plasmin 1.7
topoisomerase 1.7
alcohol dehydrogenase 1.7
glutathione reductase 1.7
luciferase 1.7
topoisomerase 1.6
aspartate aminotransferase 1.5
caspase-3 1.3
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Compound
3-hydroxyphenylalanine 10.1
3-hydroxyphenylalanine 10.1
3-hydroxyphenylalanine 10.1
3-hydroxyphenylalanine 10.1
Bathocuproine 9.8
Neocuproine 9.7
Zinc acetate 9.1
N-acetylmannosamine 8.6
IDPN 8.5
CCS 8.4
Biuret 8.3
Arsenate 8.2
copper 8.0
Usnic acid 7.9
DDM 7.7
DMM 6.8
Pamidronate 6.8
DDM 6.7
6-aminonicotinamide 6.5
UDP-GlcNAc 6.4
PMP 6.3
PMP 6.3
Cytochrome c 6.3
PMP 6.2
Clonazepam 6.1
His-Leu 6.0
Elastin 6.0
carbamic acid 5.9
VMA 5.9
Ruthenium red 5.9
TEC 5.8
SN-38 5.8
Glu-Glu 5.8
Tempol 5.6
DHPG 5.4
DBH 5.4
Benzo[a]pyrene 5.4
Parenteral 5.2
Serine 5.2
Brefeldin A 5.2
Brefeldin A 5.2
1,4,7,10-tetraazacyclododecane 5.1
Evans Blue 5.1
CPT-11 5.0
Ranitidine 5.0
DTT 4.9
DTT 4.8
Melanin 4.8
Sialic acid 4.7
ACI 4.7
cyclohexanone 4.7
cyclohexanone 4.7
cyclohexanone 4.7
cyclohexanone 4.7
cyclohexanone 4.7
Cu(II) 4.6
Heparan sulfate 4.6
cyclohexanone 4.6
CoQ 4.6
cyclohexanone 4.6
cyclohexanone 4.6
His 4.6
TTS 4.5
zinc 4.4
cadmium 4.4
Maps 4.4
Histidine 4.4
PAC 4.3
Amide 4.3
Guo 4.3
Guo 4.2
CCP 4.2
Tetracycline 4.2
folinic acid 4.1
cyclohexanone 4.1
HVA 4.1
CPT 4.1
Dopa 4.1
DOPAC 4.0
HNO3 4.0
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