Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022716 (Menkes)
 1,057 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ATP7A 260
ATPase 209
MNK 155
Wilson disease 140
X-linked 106
ceruloplasmin 92
X-linked recessive 86
ATP7B 86
Mol 86
Sep 68
MC1 62
metallothionein 53
ATP 45
eIF4E 30
MNK1 25
lysyl oxidase 24
cytochrome c oxidase 24
collagen 23
superoxide dismutase 23
MAPK 21
ATP7A protein 21
ATOX1 18
WND 17
axonal 17
prion 17
MRI 15
MNK2 13
GNE 13
p38 13
NMR 12
X-chromosome 12
endoplasmic reticulum 12
elastin 12
tyrosinase 11
polypeptide 11
mTOR 11
amyloid precursor protein 10
gut 10
ERK 9
eukaryotic translation initiation factor 4E 8
more...
Disease
Menkes 1057
Wilson's disease 80
Alzheimer's disease 47
cancer 42
tumor 24
disorders of copper metabolism 23
neuropathy 21
mental retardation 17
mental retardation 17
brain atrophy 16
amyotrophic lateral sclerosis 16
Ehlers-Danlos syndrome 15
cutis laxa 15
epilepsy 15
iron deficiency 14
genetic disorder 14
anemia 14
Parkinson's disease 13
failure to thrive 13
myopathy 12
Copper deficiency 12
developmental delay 11
malnutrition 10
encephalopathy 9
acrodermatitis enteropathica 9
cirrhosis 8
tumorigenesis 8
malabsorption 8
neurological disease 8
breast cancer 8
carcinoma 7
muscular atrophy 7
gastric cancer 7
hemochromatosis 7
prostate cancer 7
metabolic disorder 7
Huntington's disease 6
cerebral degeneration 6
fits 6
tumor growth 6
more...
Symptom
seizures 54
hypotonia 25
ataxia 14
dystonia 12
dysarthria 8
hypothermia 8
tremor 6
anesthesia 4
pain 4
emaciation 4
myoclonus 3
cerebellar ataxia 3
ophthalmoplegia 2
spasticity 2
diarrhea 2
weakness 2
lethargy 2
Blotchy 1
Kayser-Fleischer ring 1
tonic seizure 1
clumsiness 1
cough 1
starvation 1
dyspnea 1
hepatomegaly 1
athetosis 1
paraparesis 1
paresis 1
splenomegaly 1
headache 1
Neuropathic pain 1
vomiting 1
blepharospasm 1
partial seizure 1
Drug
Dermatol 19
lysine 5
MAP 3
NADH 3
ascorbate 3
Asn 3
CPT-11 2
Nephron 2
IL-2 2
CSF 2
ADR 1
Leucovorin 1
Nephron 1
Leaf 1
Orphan 1
Cardiovasc 1
Retinoic acid 1
Albumin 1
pyridoxal phosphate 1
HCH 1
ABC 1
vitamin E 1
Satraplatin 1
Dakar 1
Arsenic trioxide 1
Zinc acetate 1
Enzyme
ATPase 212
ceruloplasmin 98
mitogen-activated protein kinase 34
superoxide dismutase 25
lysyl oxidase 22
cytochrome oxidase 21
ERK 11
tyrosinase 11
CCS 7
dopamine beta-hydroxylase 5
PAM 5
catalase 4
monoamine oxidase 4
RNA polymerase 4
protein kinase 4
complex I 4
luciferase 4
MAP 3
N-acetylmannosamine kinase 3
heme oxygenase 3
caspase-3 3
MEK 3
diaphorase 3
transcriptase 3
focal adhesion kinase 2
CPR 2
diamine oxidase 2
UDP-N-acetylglucosamine 2-epimerase 2
CNPase 2
type III procollagen 2
aspartate aminotransferase 2
AtHMA4 2
ACS 2
proteasome 2
prolyl hydroxylase 2
phosphoglycerate kinase 2
succinate dehydrogenase 2
tyrosine hydroxylase 2
PGM 2
NADH dehydrogenase 1
more...
Compound
copper 778
Dec 68
DNA 65
zinc 64
His 61
Clin 60
iron 55
ATP 45
cadmium 25
cysteine 21
oxygen 19
serine 18
water 14
silver 14
calcium 13
leucine 12
acetate 11
Cu(II) 10
methionine 9
sodium 9
threonine 9
lysine 7
arginine 7
alanine 7
sulfate 7
CCS 7
manganese 7
cobalt 6
nickel 6
mercury 6
selenium 6
UDP-GlcNAc 5
Cytochrome c 5
N-acetylmannosamine 5
valine 5
Lead 5
Arsenate 5
tyrosine 4
Serine 4
noradrenaline 4
more...