Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022672 (acute tubular necrosis)
 2,175 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nonclassical MHC class I antigen 12.3
Chemokine receptor 5 10.3
hepatocyte growth factor-like 9.8
SLC27A2 9.7
A1101 9.6
MITOCHONDRIAL 9.4
GCDH 8.8
RIFLE 8.8
CHIF 8.7
NYGGF4 8.6
C-X-C motif chemokine 5 8.4
sialic acid synthase 8.4
sodium-potassium-chloride cotransporter 8.3
Fox-2 8.1
KRT7 8.1
NPT1 8.0
neutrophil gelatinase-associated lipocalin 8.0
PDK4 protein 8.0
BH3 interacting domain death agonist 7.9
KCP 7.9
Retinol-binding protein 4 7.8
CD200R1 7.8
DDAH-1 7.8
SLC6A19 7.8
PGAM5 7.8
congenital chloride diarrhea 7.7
Succinic dehydrogenase 7.7
novel zinc finger protein 7.7
IL-18BP 7.6
SIX2 7.5
MOX 7.5
PIDD 7.4
SLC22A12 7.4
TNAP 7.3
FSGS 7.3
MET protein 7.2
SALL1 7.0
EIF2AK3 7.0
sodium/hydrogen exchanger 7.0
olfactomedin 4 7.0
HRS 6.9
Interleukin-17A 6.9
integrin alpha 3 6.9
serum amyloid A protein 6.9
NGAL 6.8
NCAM1 6.8
MRP-1 6.8
CARMA1 6.7
myo-inositol oxygenase 6.7
kidney injury molecule 1 6.7
LGALS3 6.7
RFT 6.7
calcineurin inhibitor 6.7
interleukin-18 6.6
endocan 6.6
ARF 6.6
MARS 6.6
Glutathione transferase 6.6
NRF 6.5
KIM-1 6.5
gasdermin 6.5
HUS 6.4
cystathionine gamma-lyase 6.4
KEAP1 6.3
PH1 6.3
PAX2 6.3
TCP1 6.3
uromodulin 6.3
thromboxane synthase 6.2
NOK 6.2
proximal tubule 6.2
PPARA 6.2
RNA-associated 6.2
ABO blood type 6.1
HLA-A11 6.1
PME 6.1
SRL 6.1
RFI 6.1
CPT II 6.0
cholinephosphotransferase 6.0
Annexin A1 5.9
Na+/glucose cotransporter 5.9
14-3-3 sigma 5.9
N-acetyl-beta-glucosaminidase 5.9
SAPS 5.9
tyrosinase 5.9
cingulin 5.9
DCD 5.9
Stathmin 5.8
aquaporin 1 5.8
swan 5.8
leucocyte antigen 5.8
neutrophil-activating peptide-2 5.7
cubilin 5.7
DAPK 5.7
TNF-alpha converting enzyme 5.7
gasdermin D 5.7
Tamm-Horsfall glycoprotein 5.6
NLRP1 5.6
aquaporin 2 5.6
lipocortin I 5.6
NAG 5.6
PRA 5.6
chronic renal failure 5.6
melanocortin 1 receptor 5.6
ECI 5.5
semaphorin 3A 5.5
heat shock protein 72 5.5
N-acetyl-beta-D-glucosaminidase 5.5
beta 2-microglobulin 5.5
CCNB1 5.5
OAT3 5.5
myoglobin 5.4
CAN 5.4
collecting duct 5.4
OAT1 5.4
GFR 5.4
Interleukin-18 5.4
BSC-1 5.4
PGIS 5.4
RST 5.4
HTA 5.3
L1 cell adhesion molecule 5.3
DIS 5.3
TIF 5.3
Cyclophilin A 5.3
RAP 5.3
CXCL1 5.3
TIM-3 5.2
ARM 5.2
angiotensin-converting enzyme 2 5.2
urinary kallikrein 5.2
LAO 5.2
endonuclease G 5.2
RPC 5.2
heparin-binding epidermal growth factor-like growth factor 5.2
interferon-inducible protein 5.2
carboxypeptidase B 5.2
PBI 5.2
cystatin C 5.1
brush border 5.1
cyclophilin D 5.1
functional) 5.1
beta-lyase 5.1
activating transcription factor 3 5.1
TIA-1 5.0
nuclear factor (erythroid-derived 2)-like 2 5.0
ICAM-1 mRNA 5.0
megalin 5.0
atrial natriuretic factor 5.0
apoptosis regulator 5.0
DA1 5.0
renal) 4.9
Indoleamine 2,3-dioxygenase 4.9
transcortin 4.9
fas 4.9
period 3 4.9
IGF-I receptor 4.9
CysLT1 4.9
YKL-40 4.9
more...
Disease
Structural and functional abnormalities of the kidney 13.8
acute tubular necrosis 13.8
Post-infectious glomerulonephritis 11.8
Toxic myocarditis 11.5
Hantavirus nephropathy 11.5
renal artery obstruction 11.2
Renal cortical necrosis 11.0
Toxic nephropathy 10.8
Acute renal insufficiency 10.8
Perinephric abscess 10.8
Acute nephritis 10.7
Gonococcal endocarditis 10.5
potassium intoxication 10.5
Secondary oxalosis 10.4
Uremic syndrome 10.4
Renal tubular dysfunction 10.3
Chronic interstitial nephritis 10.1
interstitial nephritis 10.1
Arteriolosclerosis 10.0
Acute interstitial nephritis 9.9
juxtaglomerular cell hyperplasia 9.9
Immune complex glomerulonephritis 9.9
Fanconi-like syndrome 9.7
cholemia 9.7
hepatorenal syndrome 9.7
Acute hepatitis A 9.5
Enteric hyperoxaluria 9.5
tubular necrosis 9.5
Renal artery thrombosis 9.4
ATN 9.4
azotemia 9.4
Azotemia 9.4
Tubulointerstitial nephritis 9.4
Nephrotic range proteinuria 9.3
acute renal failure 9.3
Transient hypertension 9.2
glomerulitis 9.2
acute glomerulonephritis 9.0
Crush syndrome 8.9
Uric acid nephrolithiasis 8.9
lymphocele 8.8
Klebsiella sepsis 8.7
renal ischemia 8.7
Crescentic glomerulonephritis 8.6
renal papillary necrosis 8.5
hypotension and shock 8.4
anuria 8.4
Epstein syndrome 8.3
oxyuriasis 8.3
urinary tract obstruction 8.3
hemoglobinuria 8.3
Severe pre-eclampsia 8.3
Multicystic dysplastic kidney 8.2
Murine typhus 8.2
recurrent renal cell carcinoma 8.1
blood loss anemia 8.0
Wolcott-Rallison syndrome 8.0
Intestinal pseudo-obstruction 8.0
arteriolitis 7.8
Canine babesiosis 7.8
Bladder outlet obstruction 7.7
Infection induced 7.7
carcinoma of unknown origin 7.7
Epithelial hyperplasia 7.6
uropathy 7.6
Capillary leak syndrome 7.6
IgM nephropathy 7.5
Neisseria gonorrhoeae infection 7.5
Cytokine release syndrome 7.5
Dengue hemorrhagic fever 7.4
oxalosis 7.4
Pulmonary congestion 7.4
renin-dependent hypertension 7.4
Minimal change disease 7.4
endotheliosis 7.3
BK virus nephropathy 7.3
Acute necrotizing pancreatitis 7.3
glomerulopathy 7.3
marantic endocarditis 7.2
Hemorrhagic fever with renal syndrome 7.2
Acute fatty liver of pregnancy 7.2
pyopneumothorax 7.2
nephrosclerosis 7.1
renal failure 7.1
nephritis 7.0
glomerulonephritis 7.0
renal artery stenosis 7.0
puerperal sepsis 6.9
uricosuria 6.9
Glomerular diseases 6.9
HRS 6.9
immune complex disease 6.9
Marburg virus disease 6.9
paroxysmal nocturnal hemoglobinuria 6.9
hemolytic uremic syndrome 6.9
favism 6.8
Acute gastroenteritis 6.8
membranous nephropathy 6.8
chronic glomerulonephritis 6.8
metastatic cervical cancer 6.7
aminoaciduria 6.7
cancer angiogenesis 6.7
acute cystitis 6.7
IgA nephropathy 6.7
Gram-negative septicemia 6.7
generalized tuberculosis 6.7
nephrotic syndrome 6.7
sponge kidney 6.7
Interstitial fibrosis 6.7
Fanconi syndrome 6.6
laxative abuse 6.6
pyelonephritis 6.6
Focal segmental glomerulosclerosis 6.6
adrenalitis 6.6
Calciphylaxis 6.6
IgG myeloma 6.6
Rocky Mountain spotted fever 6.5
hypertensive nephropathy 6.5
staghorn calculus 6.5
nephrocalcinosis 6.5
Mediterranean spotted fever 6.5
primary hyperoxaluria 6.4
pyuria 6.4
DHD 6.4
Clostridium difficile colitis 6.4
nephrosis 6.4
DHD 6.4
Reye 6.4
renal disease 6.4
fluid overload 6.4
chronic renal insufficiency 6.4
glomerulosclerosis 6.4
bacterial conjunctivitis 6.4
hyperchloremia 6.4
lymphangiectasis 6.4
HELLP syndrome 6.3
PME 6.3
renal insufficiency 6.3
tumor lysis syndrome 6.3
infectious gastroenteritis 6.3
renal impairment 6.2
Nephrogenic systemic fibrosis 6.2
vascular obstruction 6.2
CAN 6.2
Plasmodium vivax infection 6.2
Drash syndrome 6.2
Spontaneous bacterial peritonitis 6.1
hemosiderosis 6.1
vascular dilation 6.1
proteinuria 6.1
moderate obesity 6.1
hypercalcemia of malignancy 6.0
acute alcoholic hepatitis 6.0
Recurrent disease 6.0
DRESS syndrome 6.0
hepatic veno-occlusive disease 6.0
methemoglobinemia 6.0
uremia 6.0
Acute infection 6.0
lower urinary tract infection 5.9
more...
Symptom
oliguria 9.3
Stinging 8.1
dark urine 7.3
loin pain 7.1
Spastic 6.4
polyuria 6.3
chyluria 6.2
giddiness 6.2
renal colic 6.2
giddiness 6.2
pedal edema 6.1
periorbital edema 5.8
hyperemesis gravidarum 5.7
flank pain 5.5
prostration 5.3
abdominal fullness 5.2
orthopnea 5.0
dysuria 4.9
stomach pain 4.9
fever of unknown origin 4.8
hypoproteinemia 4.7
leg edema 4.4
vomiting 4.2
functional recovery 4.0
flushing 4.0
nausea 3.8
emaciation 3.8
hot flashes 3.8
night sweats 3.6
respiratory distress 3.6
hypertonia 3.5
chronic constipation 3.5
shortness of breath 3.5
myalgia 3.5
paraparesis 3.4
sore throat 3.4
lethargy 3.4
hypothermia 3.3
nausea and vomiting 3.2
anorexia 3.1
diarrhea 3.1
hip pain 3.0
spasm 3.0
Ill 3.0
hepatomegaly 2.9
leg pain 2.8
chills 2.8
abdominal pain 2.6
tachypnea 2.5
constipation 2.5
knee pain 2.4
cachexia 2.4
weakness 2.3
back pain 2.3
splenomegaly 2.2
arthralgia 2.0
cyanosis 2.0
acute pain 1.9
agitation 1.9
hepatosplenomegaly 1.7
collapse 1.6
seizures 1.5
hypotonia 1.3
sleepiness 1.2
erythema 1.2
tinnitus 1.1
exhaustion 1.1
anesthesia 1.1
fatigue 1.0
acidity 0.9
tremor 0.7
syncope 0.7
dyspnea 0.6
angina 0.5
headache 0.4
cough 0.3
starvation 0.2
overweight 0.2
pain 0.1
analgesia 0.1
ataxia -0.1
chest pain -0.2
discomfort -0.6
discomfort -0.7
Drug
Naloxone HCl 10.1
Foscavir 9.4
Pemetrexed disodium 8.7
Rocaltrol 8.3
Terlipressin 8.1
Barium sulfate 8.1
Terlipressin 8.0
Fenoprofen 7.9
MEPM 7.9
Marimastat 7.7
Enprofylline 7.6
Alimta 7.5
Tenofovir disoproxil fumarate 7.4
Rasburicase 7.4
MINO 7.3
Midodrine 7.3
Tenofovir 7.2
Basiliximab 7.1
Basiliximab 7.1
Adefovir dipivoxil 6.9
PMPA 6.8
Ibandronate 6.6
Pentostam 6.5
Daclizumab 6.3
Zoledronic acid 6.2
EFV 6.2
Mesalazine 6.0
Gliclazide 6.0
Glucantime 6.0
Indinavir 5.9
EHDP 5.9
DMSA 5.9
Rasburicase 5.9
Zoledronic acid 5.9
Sodium hypochlorite 5.9
Clodronate 5.8
Nephron 5.6
Epoetin alfa 5.6
Levosimendan 5.6
Exenatide 5.5
Tacrolimus 5.5
Colistin 5.4
Optison 5.4
Pemetrexed 5.2
Nephron 5.1
Gastro 5.0
Oxaliplatin 5.0
Leucovorin 4.8
PFA 4.8
Acyclovir 4.8
Imiquimod 4.8
Oseltamivir 4.6
Meropenem 4.5
Lovastatin 4.5
NAG 4.3
PMEA 4.3
Prednisolone 4.3
Dial 4.3
Ganciclovir 4.3
Campath 4.3
Campath 4.3
Glycerol 4.2
CIA 4.2
Methylprednisolone 4.0
Aprotinin 4.0
Ringer's solution 4.0
GRF 3.9
Omeprazole 3.9
Prednisone 3.8
Doxycycline 3.7
Captopril 3.7
Serum albumin 3.6
Pronase 3.5
Rituximab 3.4
Fructose 2.9
uPA 2.8
Paraffin 2.7
Adriamycin 2.7
Silica 2.6
Albumin 2.6
Imatinib 2.6
Fraction 2.5
Nitric Oxide 2.5
ETA 2.4
Alanine 2.4
Vitamin A 2.3
Heme 2.2
Vitamin E 2.2
PTH 2.1
Glucagon 2.0
Angiotensin II 1.5
CAM 1.3
vitamin E 1.3
Indomethacin 1.2
ROS 1.2
EPA 1.0
ascorbate 0.9
ROC 0.9
ABC 0.7
IFN-gamma 0.6
IL-2 0.6
citric acid 0.6
CTX 0.5
CSF -0.1
ampicillin -0.2
Monit -0.3
caffeine -0.6
Leaf -0.6
Cardiovasc -1.8
lysine -2.0
Dermatol -4.2
Enzyme
NeuAc synthase 9.8
phosphoethanolamine cytidylyltransferase 8.8
caspase-5 7.6
caspase-5 7.3
PME 6.9
jararhagin 6.5
oxalate oxidase 6.0
cystathionine gamma-lyase 5.8
thromboxane synthase 5.7
dimethylarginine dimethylaminohydrolase 5.6
PRA 5.5
angiotensin-converting enzyme 2 5.4
prostacyclin synthase 5.3
choline kinase 5.1
adenosine kinase 5.0
aromatic L-amino acid decarboxylase 4.8
HK2 4.7
transpeptidase 4.3
alanine aminopeptidase 4.3
isoamylase 4.3
acyl-CoA dehydrogenase 4.2
granzyme B 4.1
TSP-1 4.1
C3 convertase 4.0
C3 convertase 3.8
neuropathy target esterase 3.8
kallikrein 3.6
creatine kinase 3.5
adenosine deaminase 3.5
adenosine deaminase 3.5
ACE 3.5
MDP 3.4
acyl-CoA dehydrogenase 3.4
gamma-glutamylcysteine synthetase 3.4
leucine aminopeptidase 3.2
dipeptidyl peptidase IV 3.1
PTA 3.1
renin 3.1
calcineurin 3.1
CPT 3.1
AOR 3.1
CD13 3.0
gamma-glutamyl transpeptidase 3.0
prostaglandin synthetase 3.0
PDE 3.0
arginase 3.0
PAM 3.0
AST 2.9
neutrophil elastase 2.8
paraoxonase 2.8
caspase-1 2.8
heme oxygenase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.7
CAD 2.7
glyceraldehyde-3-phosphate dehydrogenase 2.7
matrix metalloproteinase 9 2.7
PAH 2.7
CAD 2.7
PDK1 2.7
CAD 2.7
hyaluronidase 2.7
glyceraldehyde-3-phosphate dehydrogenase 2.6
phospholipase A2 2.6
aspartate aminotransferase 2.6
alanine aminotransferase 2.6
BMT 2.5
lactate dehydrogenase 2.5
glyceraldehyde-3-phosphate dehydrogenase 2.4
isocitrate dehydrogenase 2.2
hyaluronidase 2.2
CYP3A4 2.2
glyceraldehyde-3-phosphate dehydrogenase 2.2
caspase-8 2.1
isocitrate dehydrogenase 2.1
aldolase 2.1
superoxide dismutase 2.1
beta-glucuronidase 1.9
xanthine oxidase 1.8
aldehyde dehydrogenase 1.7
aldehyde dehydrogenase 1.7
aldehyde dehydrogenase 1.7
caspase-3 1.7
PARP 1.7
CPT 1.7
MIP 1.6
ceruloplasmin 1.5
aldehyde dehydrogenase 1.5
urokinase-type plasminogen activator 1.5
pyruvate dehydrogenase 1.4
catalase 1.4
phosphorylase 1.4
glutathione S-transferase 1.4
tissue plasminogen activator 1.4
alkaline phosphatase 1.3
aldehyde dehydrogenase 1.2
ribonuclease 1.2
ribonuclease 1.1
thromboplastin 1.1
lysozyme 1.0
peroxidase 1.0
beta-galactosidase 1.0
carbonic anhydrase 1.0
NO synthase 0.9
reverse transcriptase 0.9
APC 0.8
succinate dehydrogenase 0.8
RNase 0.8
pepsin 0.8
RNase 0.7
alcohol dehydrogenase 0.7
ATPase 0.4
chymotrypsin 0.4
glutathione peroxidase 0.4
phosphatidylinositol 3-kinase 0.4
acid phosphatase 0.2
AMP-activated protein kinase 0.2
mitogen-activated protein kinase 0.1
acetylcholinesterase 0.0
tyrosine hydroxylase -0.0
thrombin -0.2
MEK -0.3
lipase -0.3
phosphodiesterase -0.4
ERK -0.4
trypsin -0.5
protein kinase -0.9
luciferase -1.4
focal adhesion kinase -1.6
protein kinase C -1.7
Compound
Djenkolic acid 12.8
Coniine 9.9
Sporidesmin 9.8
NDPS 9.3
Hippuran 9.0
Cephaloridine 8.9
Fast Red TR 8.7
Cephapirin 8.6
Fenoprofen 8.1
PTSM 8.0
Acephate 7.8
Midodrine 7.7
Sulfadoxine 7.2
Diatrizoate 7.1
Diatrizoate 7.1
creatinine 7.0
Sulfinpyrazone 7.0
Meglumine 6.8
Sulfatide 6.8
Pamidronate 6.8
N-methylnicotinamide 6.8
WY-14,643 6.7
Calcium carbonate 6.6
DCVC 6.6
Phalloidin 6.4
Gentamicin 6.4
Nobiletin 6.3
hippurate 6.2
Domoic acid 6.2
Aristolochic acid 6.2
Cefoxitin 6.1
Lopinavir 6.1
DTPA 6.1
DBCP 6.1
Foscarnet 6.1
Deoxycoformycin 6.0
HgCl2 6.0
Salinomycin 6.0
Selectin 6.0
isopentane 6.0
Indinavir 5.9
Pepstatin 5.9
Pentamidine 5.9
HBC 5.9
Cyclosporine 5.8
CPH 5.8
Cystathionine 5.7
CAN 5.7
Cystathionine 5.7
Polymyxin B 5.6
MeCCNU 5.6
NaAsO2 5.6
tetraethyl orthosilicate 5.6
M 2 5.4
2(5H)-furanone 5.3
urea 5.3
ANCA 5.3
DDP 5.2
Oseltamivir 5.2
Vancomycin 5.2
neopterin 5.1
EHDP 5.1
Lawson 5.1
Naringin 4.9
Endosulfan 4.9
PMEA 4.9
SDA 4.9
Triptolide 4.9
Telmisartan 4.9
Antimycin 4.9
Paraquat 4.9
Acyclovir 4.8
Ifosfamide 4.8
PCN 4.8
Aminophylline 4.8
Tobramycin 4.7
PVP-I 4.7
Paraquat 4.7
Dipyridamole 4.7
Dipyridamole 4.7
Dipyridamole 4.7
Dipyridamole 4.7
A 42 4.6
Factor H 4.6
Mycophenolate mofetil 4.6
oxalate 4.6
Fenofibrate 4.6
Hemin 4.5
Hemin 4.5
Hemin 4.5
Hemin 4.5
Mannitol 4.5
EPC 4.5
Glucosamine 4.4
Mannitol 4.4
CBDCA 4.4
CBDCA 4.4
Hemin 4.4
FK506 4.3
Ciprofloxacin 4.3
Prednisolone 4.3
Amikacin 4.3
APAP 4.2
DOP 4.2
Dial 4.2
Pentoxifylline 4.2
Dextran 4.2
Formate 4.2
AICAR 4.1
HIS 4.1
Methylprednisolone 4.1
DDC 4.0
E-64 4.0
Salix 3.9
Azathioprine 3.8
Ochratoxin A 3.8
Mendel 3.8
Doxycycline 3.8
Rapamycin 3.7
Coronal 3.7
Omeprazole 3.6
DPP 3.6
Ribavirin 3.6
XTT 3.6
Diltiazem 3.6
Diltiazem 3.6
POP 3.5
Vimentin 3.5
Hypaque 3.5
DFO 3.5
DIC 3.5
Malondialdehyde 3.5
prostaglandin F1 3.5
Adenosine 3.4
Thymidine 3.4
nitrogen 3.4
MMA 3.4
retinol 3.4
Uric acid 3.4
HPP 3.4
tellurium 3.3
Guanine 3.3
Interleukin-2 3.3
bis(2-chloroethyl) 3.3
Adenine 3.3
AICAR 3.3
PCE 3.3
D-glucosamine 3.3
DPA 3.3
DPA 3.3
DPA 3.3
DPA 3.3
TMA 3.3
DPA 3.3
Thyroxine 3.3
TMA 3.3
MCA 3.3
MCA 3.2
PAS 3.2
PAP 3.2
more...