Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022672 (acute tubular necrosis)
 2,175 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 133
chronic renal failure 44
cytokine 44
proximal tubule 42
HLA 34
tyrosinase 33
albumin 33
She 30
Mol 29
myoglobin 27
renin 21
neutrophil gelatinase-associated lipocalin 20
hemoglobin 19
IL-6 17
TNF 17
ARF 17
brush border 16
tumor necrosis factor 16
CD4 16
collecting duct 15
superoxide dismutase 15
vimentin 14
calcineurin inhibitor 14
IgA 12
epidermal growth factor 12
GFR 12
ATP 11
HLA-DR 10
calcineurin 10
chemokine 10
beta 2-microglobulin 10
caspase-3 10
lactate dehydrogenase 10
hepatocyte growth factor 10
insulin 9
CD8 9
atrial natriuretic factor 9
inducible nitric oxide synthase 9
catalase 9
calcium channel 9
collagen 8
alkaline phosphatase 8
RIFLE 8
cystatin C 8
heme oxygenase-1 8
serum albumin 8
myeloperoxidase 7
glycoprotein 7
angiotensin II 7
creatine kinase 7
endoplasmic reticulum 7
erythropoietin 7
nitric oxide synthase 7
TNF-alpha 7
ACE 7
IL-10 7
GSH 7
aspartate aminotransferase 6
phospholipase A2 6
Bcl-2 6
SARS 6
lipopolysaccharide 6
alanine aminotransferase 6
CD133 6
NMR 6
vasopressin 6
MCP-1 6
interleukin-18 6
transforming growth factor-beta 6
cyclooxygenase 6
interleukin-6 6
LDH 6
MRI 6
CXCL1 6
C-reactive protein 6
lymphoid 6
fibronectin 5
MRS 5
PRA 5
atrial natriuretic peptide 5
N-acetyl-beta-D-glucosaminidase 5
heat shock protein 5
NGAL 5
SOD 5
fibrinogen 5
intercellular adhesion molecule-1 5
proliferating cell nuclear antigen 5
poly(ADP-ribose) polymerase 5
smooth muscle actin 4
HRS 4
CD11b 4
HLA class I 4
Ki-67 4
ferritin 4
TLR4 4
granzyme B 4
E-selectin 4
interleukin-2 receptor 4
angiotensin receptor 4
angiotensinogen 4
HLA-A 4
adhesion molecule 4
human leukocyte antigen 4
angiotensin-converting enzyme 2 4
IGF-I receptor 4
endothelin receptor 4
cytochrome 4
adenosine deaminase 4
Pol 4
PK1 4
CD24 4
perforin 4
ATPase 4
interferon 4
ICAM-1 4
amylase 4
EGF 4
insulin-like growth factor-I 4
CD34 4
SDS 4
IL-33 4
major histocompatibility complex 4
CD68 4
kallikrein 4
lectin 3
CXCR4 3
Tumor necrosis factor 3
IL-8 3
alpha-smooth muscle actin 3
aminopeptidase 3
transferrin 3
tissue factor 3
IGF-I 3
metallothionein 3
CHOP 3
AST 3
endothelin-1 3
ROS 3
CD20 3
thromboxane synthase 3
NAG 3
gamma-glutamyl transpeptidase 3
cyclooxygenase-2 3
IFN-gamma 3
insulin-like growth factor 3
PARP-1 3
p38 3
PME 3
AMP 3
TLR2 3
CPK 3
methemoglobin 3
platelet-derived growth factor 3
caspase-8 3
stem cell factor 3
HUS 3
urinary kallikrein 3
natriuretic peptide 3
N-acetyl-beta-glucosaminidase 3
microsomal 3
more...
Disease
acute tubular necrosis 2175
acute renal failure 528
renal failure 307
renal disease 263
ischemia 195
interstitial nephritis 178
glomerulonephritis 126
proteinuria 109
sepsis 98
sepsis 90
azotemia 84
hypertension 79
cold 76
nephrotic syndrome 71
renal ischemia 70
chronic renal failure 63
tubular necrosis 62
nephritis 60
hepatorenal syndrome 56
renal insufficiency 50
diabetes 49
cirrhosis 45
cancer 44
glomerulosclerosis 43
pyelonephritis 40
vasculitis 38
ATN 33
renal impairment 32
anuria 32
cytomegalovirus 32
HIV 31
anemia 30
dehydration 28
IgA nephropathy 27
liver disease 27
hemolytic uremic syndrome 27
tumor 26
uremia 26
glomerulopathy 25
disseminated intravascular coagulation 25
malaria 25
renal artery stenosis 24
membranous nephropathy 23
urinary tract obstruction 23
uropathy 23
heart failure 22
acute glomerulonephritis 22
pneumonia 21
urinary tract infection 21
coma 21
hydronephrosis 20
thrombocytopenia 20
ARF 19
immunodeficiency 19
multiple myeloma 18
hemolytic anemia 17
pulmonary edema 16
lymphocele 16
lupus nephritis 16
virus infection 15
infectious diseases 15
AIDS 15
amyloidosis 14
hypercalcemia 13
paroxysmal nocturnal hemoglobinuria 13
hemoglobinuria 13
carcinoma 13
hepatitis 13
chronic renal insufficiency 12
hepatitis A 12
diabetic nephropathy 12
congestive heart failure 12
fluid overload 12
hyperbilirubinemia 11
renal cell carcinoma 11
Infection 11
polycystic kidney 11
respiratory failure 11
coagulopathy 11
SEM 11
Fanconi syndrome 11
rash 11
lymphoma 10
systemic lupus erythematosus 10
chronic liver disease 10
Fanconi 10
preeclampsia 10
chronic glomerulonephritis 10
glomerulitis 9
stroke 9
wasting 9
encephalopathy 9
lupus 9
nephrosis 9
peritonitis 9
nephrocalcinosis 9
vascular disease 8
hepatitis B 8
dysplasia 8
obesity 8
gastroenteritis 8
myocardial infarction 8
Legionella 8
nephrosclerosis 8
adult respiratory distress syndrome 8
depression 8
leprosy 8
hypoglycemia 8
tuberculosis 8
dengue 8
pancreatitis 8
cardiovascular disease 7
thrombocytopenic purpura 7
acute hepatitis 7
Acute interstitial nephritis 7
GSH 7
fits 7
renal papillary necrosis 7
eosinophilia 7
rheumatoid arthritis 7
compartment syndrome 7
lupus 7
SARS 7
metastases 7
urolithiasis 6
obstructive jaundice 6
systemic disease 6
bacteremia 6
abortion 6
pyuria 6
Epstein 6
HELLP syndrome 6
coronary artery disease 6
leptospirosis 6
deep vein thrombosis 6
fatty liver 6
ureter 6
MRS 5
Infections 5
sarcoidosis 5
influenza 5
hemosiderosis 5
myocarditis 5
acute myocardial infarction 5
type 2 diabetes 5
drug withdrawal 5
hyperglycemia 5
arteriosclerosis 5
typhoid 5
acute pancreatitis 5
bacterial peritonitis 5
Acute renal insufficiency 5
methemoglobinemia 5
Proteinuria 5
renal artery obstruction 5
renal tubular acidosis 5
nephrolithiasis 5
atherosclerosis 5
lactic acidosis 5
Azotemia 4
more...
Symptom
oliguria 82
vomiting 39
diarrhea 33
nausea 23
pain 19
polyuria 16
respiratory distress 16
anesthesia 16
seizures 15
functional recovery 15
abdominal pain 13
weakness 13
hypothermia 12
anorexia 8
flushing 7
flank pain 7
fatigue 7
nausea and vomiting 6
collapse 6
Ill 6
headache 5
dysuria 5
myalgia 5
spasm 4
back pain 4
shortness of breath 4
lethargy 4
fever of unknown origin 4
renal colic 4
constipation 4
splenomegaly 3
dyspnea 3
loin pain 3
dark urine 3
agitation 3
hepatomegaly 3
sleepiness 2
sore throat 2
acidity 2
tremor 2
cachexia 2
starvation 2
analgesia 2
chills 2
hyperemesis gravidarum 2
overweight 2
angina 2
arthralgia 2
hypoproteinemia 2
paraparesis 2
erythema 2
exhaustion 2
cough 2
stomach pain 1
hot flashes 1
cyanosis 1
discomfort 1
chyluria 1
emaciation 1
pedal edema 1
leg pain 1
periorbital edema 1
hepatosplenomegaly 1
Spastic 1
tachypnea 1
knee pain 1
hypertonia 1
giddiness 1
hip pain 1
acute pain 1
discomfort 1
hypotonia 1
prostration 1
abdominal fullness 1
syncope 1
chest pain 1
giddiness 1
leg edema 1
orthopnea 1
night sweats 1
Stinging 1
ataxia 1
chronic constipation 1
tinnitus 1
Drug
Nephron 41
Dial 41
Nephron 40
PMPA 6
Tacrolimus 5
Zoledronic acid 4
Cardiovasc 4
Tenofovir 4
vitamin E 3
IFN-gamma 3
DMSA 3
Glycerol 3
ascorbate 3
ROS 3
NAG 3
Ringer's solution 3
IL-2 3
Zoledronic acid 2
Monit 2
Gastro 2
PFA 2
EHDP 2
Prednisolone 2
Rituximab 2
Lovastatin 2
Oxaliplatin 2
Terlipressin 2
CSF 2
Adriamycin 2
Captopril 2
PTH 2
Terlipressin 2
Tenofovir disoproxil fumarate 2
Acyclovir 2
Albumin 2
Colistin 2
EFV 1
Prednisone 1
Enprofylline 1
Campath 1
Alanine 1
ABC 1
Barium sulfate 1
ampicillin 1
citric acid 1
ETA 1
Sodium hypochlorite 1
CAM 1
Methylprednisolone 1
Leaf 1
Daclizumab 1
Ibandronate 1
Basiliximab 1
Gliclazide 1
Alimta 1
Vitamin A 1
PMEA 1
Pronase 1
Glucantime 1
Marimastat 1
Epoetin alfa 1
Naloxone HCl 1
Adefovir dipivoxil 1
Optison 1
Fenoprofen 1
Midodrine 1
CIA 1
Silica 1
Foscavir 1
Clodronate 1
ROC 1
Doxycycline 1
Vitamin E 1
Nitric Oxide 1
Imatinib 1
Dermatol 1
Aprotinin 1
Campath 1
Pemetrexed 1
uPA 1
Indinavir 1
Exenatide 1
Fructose 1
caffeine 1
Fraction 1
Paraffin 1
Omeprazole 1
Mesalazine 1
GRF 1
Heme 1
Imiquimod 1
MEPM 1
Oseltamivir 1
Glucagon 1
Rocaltrol 1
Rasburicase 1
CTX 1
Basiliximab 1
Leucovorin 1
lysine 1
Angiotensin II 1
Pentostam 1
Serum albumin 1
MINO 1
EPA 1
Ganciclovir 1
Meropenem 1
Pemetrexed disodium 1
Indomethacin 1
Levosimendan 1
Rasburicase 1
Enzyme
renin 21
superoxide dismutase 17
creatine kinase 15
ACE 14
alanine aminotransferase 11
lactate dehydrogenase 11
catalase 10
calcineurin 10
peroxidase 9
aspartate aminotransferase 9
alkaline phosphatase 8
caspase-3 8
mitogen-activated protein kinase 7
phospholipase A2 6
ATPase 6
ERK 5
gamma-glutamyl transpeptidase 5
kallikrein 5
PRA 5
glutathione S-transferase 4
adenosine deaminase 4
granzyme B 4
reverse transcriptase 4
adenosine deaminase 4
angiotensin-converting enzyme 2 3
AST 3
protein kinase 3
PME 3
PARP 3
lysozyme 3
caspase-1 3
hyaluronidase 2
CAD 2
thrombin 2
CAD 2
thromboplastin 2
cystathionine gamma-lyase 2
caspase-8 2
beta-glucuronidase 2
tissue plasminogen activator 2
APC 2
urokinase-type plasminogen activator 2
NO synthase 2
hyaluronidase 2
thromboxane synthase 2
RNase 2
PDE 2
glyceraldehyde-3-phosphate dehydrogenase 2
arginase 2
xanthine oxidase 2
CPT 2
heme oxygenase 2
PAH 2
RNase 2
glyceraldehyde-3-phosphate dehydrogenase 2
neutrophil elastase 2
acetylcholinesterase 2
transpeptidase 2
glutathione peroxidase 2
adenosine kinase 2
CD13 2
glyceraldehyde-3-phosphate dehydrogenase 2
CYP3A4 2
beta-galactosidase 2
trypsin 2
glyceraldehyde-3-phosphate dehydrogenase 2
CAD 2
MDP 2
glyceraldehyde-3-phosphate dehydrogenase 2
alcohol dehydrogenase 1
PTA 1
HK2 1
caspase-5 1
acid phosphatase 1
C3 convertase 1
isoamylase 1
phosphorylase 1
aldehyde dehydrogenase 1
focal adhesion kinase 1
acyl-CoA dehydrogenase 1
isocitrate dehydrogenase 1
ribonuclease 1
aldehyde dehydrogenase 1
lipase 1
BMT 1
protein kinase C 1
phosphodiesterase 1
isocitrate dehydrogenase 1
TSP-1 1
ceruloplasmin 1
caspase-5 1
neuropathy target esterase 1
ribonuclease 1
PDK1 1
gamma-glutamylcysteine synthetase 1
prostacyclin synthase 1
dimethylarginine dimethylaminohydrolase 1
matrix metalloproteinase 9 1
acyl-CoA dehydrogenase 1
phosphoethanolamine cytidylyltransferase 1
phosphatidylinositol 3-kinase 1
pepsin 1
aldolase 1
oxalate oxidase 1
carbonic anhydrase 1
leucine aminopeptidase 1
alanine aminopeptidase 1
pyruvate dehydrogenase 1
AMP-activated protein kinase 1
paraoxonase 1
dipeptidyl peptidase IV 1
prostaglandin synthetase 1
chymotrypsin 1
MIP 1
AOR 1
succinate dehydrogenase 1
aromatic L-amino acid decarboxylase 1
aldehyde dehydrogenase 1
aldehyde dehydrogenase 1
aldehyde dehydrogenase 1
choline kinase 1
C3 convertase 1
jararhagin 1
tyrosine hydroxylase 1
PAM 1
NeuAc synthase 1
luciferase 1
MEK 1
CPT 1
Compound
creatinine 511
Clin 251
urea 174
Dec 143
sodium 137
nitrogen 112
water 67
oxygen 55
calcium 45
Dial 39
potassium 35
DTPA 33
phosphate 32
DNA 31
glucose 30
His 25
nitric oxide 21
Cyclosporine 20
glycerol 20
DDP 19
salt 19
TNF 17
oxalate 17
iron 15
phosphorus 12
ATP 11
Gentamicin 11
ethanol 10
HgCl2 10
arginine 10
sulfate 9
aldosterone 9
acetate 9
cysteine 9
PEG 8
FK506 8
iodine 8
APAP 7
GSH 7
retinol 7
noradrenaline 7
serine 7
copper 7
GSH 7
mercury 7
Vancomycin 6
galactose 6
PEG 6
Cardiol 6
silver 6
Hippuran 6
EDTA 5
hippurate 5
ANCA 5
CO2 5
nitrate 5
A 42 5
leucine 5
Adenosine 5
neopterin 5
SDS 4
6-12 4
N-acetylcysteine 4
PAS 4
Salix 4
chromium 4
EDTA 4
ammonia 4
Phe 3
tetraethyl orthosilicate 3
AMP 3
methionine 3
alanine 3
CAN 3
CCl4 3
Ciprofloxacin 3
Dextran 3
prostaglandin E1 3
NDPS 3
Sodium 3
ADP 3
zinc 3
Rapamycin 3
PGE2 3
adenylate 3
silicon 3
Cephaloridine 3
DMSO 3
hydrogen 3
DIC 2
MDA 2
nicotinamide 2
Cefoxitin 2
Dopamine 2
Paraquat 2
ammonium 2
Malondialdehyde 2
H2O2 2
CBDCA 2
Vimentin 2
Dipyridamole 2
Dipyridamole 2
Mannitol 2
HCl 2
tyrosine 2
PAP 2
threonine 2
H2S 2
Mannitol 2
fluorine 2
gamma-aminobutyric acid 2
MCA 2
chlorine 2
propylene glycol 2
NADPH 2
Polymyxin B 2
Selectin 2
PAP 2
Asp 2
CAM 2
chromate 2
MCA 2
phenol 2
PAH 2
Gly 2
DPP 2
Adriamycin 2
Dipyridamole 2
CBDCA 2
glutamate 2
Calcium carbonate 2
Resveratrol 2
GMP 2
NADPH 2
2-oxoglutarate 2
Melatonin 2
Pamidronate 2
Isoproterenol 2
propylene glycol 2
prostacyclin 2
Angiotensin II 2
Acyclovir 2
Mg2+ 2
acetic acid 2
Salt 2
Paraquat 2
naphthalene 2
selenium 2
Phalloidin 2
Dipyridamole 2
cyanide 2
sodium chloride 2
Lactate 2
Prednisolone 2
acetone 2
2(5H)-furanone 1
Sulfatide 1
AICAR 1
NH2 1
Casein 1
more...