Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022672 (acute tubular necrosis)
 2,175 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The FENa test, a determination of the excreted fraction of the filtered sodium, was performed in patients in the oliguric phase of acute renal failure. Patients with prerenal azotemia had an FENa of less than 1, and patients with acute tubular necrosis had an FENa of more than 3 (P less than .001). This simple test clearly differentiates between these two conditions and, thus, is of considerable clinical value.
JAMA 1976 Aug 09
PMID:The FENa test. Use in the differential diagnosis of acute renal failure. 94 39

Acute renal tubular necrosis occurred in this 19-year-old white female after severe hypotension developed as the result of massive pulmonary emboli and failure of the right side of the heart. This previously healthy young girl was 19 days into her first cycle of an oral estrogen-progestogen agent. Upon admission to the hospital she was in critical condition, and 4 hours after admission cardiopulmonary resuscitation was necessary. 34 days after admission she developed ventricular tachycardia during a cardiac catheterization. Hemodialyses were instituted twice, with ventricular fibrillation occurring during the first procedure, which required cardiac defibrillation. Hemiparesis of the left side developed after this episode. She was discharged after 58 days with some left-sided weakness. After 9 months the pulmonary lesions had cleared and her electrocardiogram was normal.
JAMA 1967 Apr 10
PMID:Acute renal tubular necrosis; a complication of pulmonary thromboembolism. 1227 13