Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0022575 (keratoconjunctivitis sicca)
772 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein lacrimal 126 HRD 82 Sep 48 SS-A 36 SS-B 32 rheumatoid factor 31 lactoferrin 21 lysozyme 19 SSA 17 SSB 16 mucin 16 interferon 15 lamp 14 IgA 14 lymphoid 13 She 12 cytokine 10 HLA 9 long chain 9 collagen 8 Rec 8 LL) 7 Fas 6 PKR 6 Mol 5 fibronectin 5 ANA 5 NOD 5 CD4 5 insulin 4 AQP5 4 Rheumatoid factor 4 epidermal growth factor 4 Cytokine 4 IFN 4 IL-6 4 MUC5AC 3 lectin 3 p68 kinase 3 all-trans 3 HLA-DR4 3 TNF 3 STAT1 3 amylase 3 RNP 3 HLA-DR 3 p48 3 MRI 3 CD8 3 CD25 3 ribonucleoprotein 3 bcl-2 3 prealbumin 2 B10 2 caspase-3 2 glycoprotein 2 lipase 2 alpha-fodrin 2 endoplasmic reticulum 2 MMP-9 2 polypeptide 2 TSP 2 granzyme A 2 DES 2 chronic renal failure 2 bax 2 APO-1 2 STAT2 2 alternatively spliced 2 ACTH 2 Sp1 2 cytokeratin 2 adenosine deaminase 2 chemokine 2 perforin 2 DR4 2 HLA-DR3 2 membrane-bound 2 SDS 2 peroxidase 2 more...

Disease keratoconjunctivitis sicca 772 xerostomia 158 KCS 82 autoimmune disease 77 cornea 59 rheumatoid arthritis 56 conjunctiva 43 systemic lupus erythematosus 41 conjunctivitis 36 keratitis 34 arthritis 34 vasculitis 32 Sjogren's syndrome 26 uveitis 25 sialadenitis 23 cataract 22 graft-versus-host disease 22 glaucoma 19 blepharitis 18 dry eye syndrome 18 tumor 18 lymphoma 17 connective tissue disease 17 PSS 17 keratopathy 16 scleroderma 16 cancer 15 keratoconjunctivitis 15 systemic disease 14 neuropathy 14 anterior uveitis 14 Cornea 14 scleritis 14 Cornea 14 corneal ulcer 13 pemphigoid 13 lupus 13 Raynaud's phenomenon 13 epiphora 13 Stevens-Johnson syndrome 12 eye disease 12 episcleritis 12 xerophthalmia 11 sarcoidosis 11 lymphadenopathy 10 lupus 10 sicca syndrome 9 immunodeficiency 9 prolapse 9 primary biliary cirrhosis 9 blindness 8 amyloidosis 8 diabetes 8 HIV 7 anemia 7 optic neuritis 7 rosacea 6 parotitis 6 dermatitis 6 interstitial pneumonia 6 intraocular pressure 6 hypergammaglobulinemia 6 pruritus 6 hypothyroidism 6 iridocyclitis 5 fibromyalgia 5 polymyositis 5 autonomic neuropathy 5 NOD 5 hepatitis 5 trichiasis 5 osteoarthritis 5 dental caries 5 multiple sclerosis 5 proptosis 5 dacryocystitis 5 pancreatitis 5 dacryoadenitis 5 renal disease 4 interstitial nephritis 4 more...

Symptom dry eye 123 discomfort 21 discomfort 21 pain 16 fatigue 13 thinning 8 photophobia 6 seizures 6 anesthesia 6 sialectasis 5 blepharospasm 5 arthralgia 4 myalgia 4 blurred vision 3 splenomegaly 3 erythema 3 weakness 3 agitation 2 numbness 2 cough 2 diarrhea 2 dysesthesia 2 eye pain 2 dyspnea 2 vomiting 2 Kayser-Fleischer ring 1 spasm 1 finger pain 1 DNA marker 1 back pain 1 livedo 1 dystonia 1 partial seizure 1 polymyalgia 1 overweight 1 dizziness 1 eye discharge 1 angina 1 polyuria 1 hoarseness 1 fasciculation 1 sciatica 1 enuresis 1 adenitis 1 aniseikonia 1 tingling 1 functional recovery 1 shortness of breath 1 abdominal discomfort 1 headache 1 abdominal pain 1 hemoptysis 1 colic 1 epigastric pain 1

Drug Dermatol 4 Fluorescein 3 Fluorescein 3 Pilocarpine 2 Prednisolone 2 Asthma 2 Sodium hyaluronate 2 ascorbate 2 Rituximab 2 Retinoic Acid 1 Sucralfate 1 Citric acid 1 Growth hormone 1 Ketoconazole 1 lysine 1 IFN-gamma 1 Tuberculin 1 Albumin 1 CTX 1 Cellulose acetate 1 Methylcellulose 1 Forskolin 1 Growth hormone 1 Tacrolimus 1 Vitamin A 1 Ketalar 1 Prednisone 1 uPA 1 PTH 1 Secretin 1 Retinoic acid 1 Solcoseryl 1 ADM 1 ROC 1 MgSO4 1 DM1 1 NOV 1 KCL 1

Enzyme lysozyme 19 protein kinase 7 fatty acid elongase 5 acyl-CoA synthetase 5 TSP-1 3 focal adhesion kinase 3 mitogen-activated protein kinase 3 lipase 2 caspase-3 2 estrogen sulfotransferase 2 adenosine deaminase 2 ribonuclease 2 chloramphenicol acetyltransferase 2 peroxidase 2 ribonuclease 2 RNase 2 RNase 2 adenosine deaminase 2 ERK 2 alanyl-tRNA synthetase 1 urokinase-type plasminogen activator 1 neuraminidase 1 CAD 1 4CL 1 phosphoinositide 3-kinase 1 citrate synthase 1 ACE 1 fatty acyl-CoA reductase 1 PAL 1 ascorbate peroxidase 1 histidyl-tRNA synthetase 1 MEK 1 condensing enzyme 1 PDE 1 superoxide dismutase 1 glutamate decarboxylase 1 RNA polymerase 1 fatty-acyl-CoA synthase 1 elastase 1 adenylate cyclase 1 reverse transcriptase 1 CAD 1 PAL 1 CAD 1 TRS 1 alanine aminotransferase 1 glycerophosphate acyltransferase 1 trypsin 1 creatine kinase 1 carbonic anhydrase 1 plasmin 1

Compound Clin 70 Dec 39 sodium 22 DNA 17 Rose Bengal 13 water 12 sulfate 8 hyaluronic acid 6 retinoic acid 6 ANA 5 CoA 5 Cyclosporine 5 salt 5 ANA 5 calcium 4 sodium chloride 3 Lip 3 glucose 3 acetate 3 potassium 3 phenol 3 oxygen 3 PAS 3 pyrimidine 3 TNF 3 pyrimidine 3 Retinal 3 lysine 2 PVA 2 Thyroid 2 FK506 2 DES 2 His 2 Estrogen 2 glycerol 2 malonyl-CoA 2 ACTH 2 copper 2 Prednisolone 2 SDS 2 CO2 2 Isoproterenol 2 propylene glycol 1 aldehyde 1 phosphate 1 nitrogen 1 iodine 1 fluorine 1 Ketoconazole 1 Neu5,9Ac2 1 Salt 1 Cellulose 1 CIT 1 SAH 1 cAMP 1 GMP 1 INH 1 acetic acid 1 DBA 1 SP-1 1 iron 1 Phytol 1 guanidine 1 1,3,5-triazine 1 MTT 1 Lidocaine 1 retinol 1 octyl 1 galactose 1 silver 1 NADPH 1 chlorine 1 PSP 1 Nitrazepam 1 octyl 1 GlcNAc 1 MIT 1 ADP 1 Acyl-CoA 1 urea 1 more...

---