Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022575 (keratoconjunctivitis sicca)
 772 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lacrimal 126
HRD 82
Sep 48
SS-A 36
SS-B 32
rheumatoid factor 31
lactoferrin 21
lysozyme 19
SSA 17
mucin 16
SSB 16
interferon 15
IgA 14
lamp 14
lymphoid 13
She 12
cytokine 10
long chain 9
HLA 9
collagen 8
more...
Disease
keratoconjunctivitis sicca 772
xerostomia 158
KCS 82
autoimmune disease 77
cornea 59
rheumatoid arthritis 56
conjunctiva 43
systemic lupus erythematosus 41
conjunctivitis 36
arthritis 34
keratitis 34
vasculitis 32
Sjogren's syndrome 26
uveitis 25
sialadenitis 23
cataract 22
graft-versus-host disease 22
glaucoma 19
tumor 18
blepharitis 18
more...
Symptom
dry eye 123
discomfort 21
discomfort 21
pain 16
fatigue 13
thinning 8
anesthesia 6
seizures 6
photophobia 6
sialectasis 5
blepharospasm 5
arthralgia 4
myalgia 4
splenomegaly 3
erythema 3
blurred vision 3
weakness 3
dysesthesia 2
cough 2
numbness 2
more...
Drug
Dermatol 4
Fluorescein 3
Fluorescein 3
Rituximab 2
Pilocarpine 2
Asthma 2
Prednisolone 2
Sodium hyaluronate 2
ascorbate 2
Retinoic Acid 1
Solcoseryl 1
Sucralfate 1
uPA 1
CTX 1
IFN-gamma 1
lysine 1
Cellulose acetate 1
Tacrolimus 1
Vitamin A 1
PTH 1
more...
Enzyme
lysozyme 19
protein kinase 7
acyl-CoA synthetase 5
fatty acid elongase 5
focal adhesion kinase 3
mitogen-activated protein kinase 3
TSP-1 3
estrogen sulfotransferase 2
lipase 2
ERK 2
ribonuclease 2
adenosine deaminase 2
chloramphenicol acetyltransferase 2
ribonuclease 2
RNase 2
peroxidase 2
adenosine deaminase 2
caspase-3 2
RNase 2
alanyl-tRNA synthetase 1
more...
Compound
Clin 70
Dec 39
sodium 22
DNA 17
Rose Bengal 13
water 12
sulfate 8
hyaluronic acid 6
retinoic acid 6
ANA 5
CoA 5
salt 5
ANA 5
Cyclosporine 5
calcium 4
oxygen 3
Retinal 3
phenol 3
potassium 3
pyrimidine 3
more...