Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0022575 (
keratoconjunctivitis sicca
)
772
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two patients with
Goldenhar syndrome
developed corneal ulcers. Previous acid burn of the cornea and prolonged topical corticosteroid administration occurred in Patient 1. Predisposing ocular anomalies in patients with
Goldenhar syndrome
include corneal hypesthesia;
keratoconjunctivitis sicca
, and exposure secondary to eyelid colobomas, lacrimal gland and duct anomalies, dermoids and lipodermoids, and neurologic deficits. Serious ocular morbidity may be prevented by searching for and adequately treating these predisposing factors. It is possible that embryonic events contribute to ocular complications in
Goldenhar syndrome
, in part, by causing hypoplasia or abnormal function of the trigeminal and facial nerves.
...
PMID:Corneal ulcers associated with Goldenhar syndrome. 33 60
