Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022568 (keratitis)
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Human Gene/Protein
IQCF3 12.6
guanine nucleotide-releasing factor 2 12.6
NAT12 11.6
lymphocyte cytosolic protein 2 11.0
C21orf91 11.0
lacritin 9.9
RelA-associated inhibitor 9.8
JDP1 9.7
KID 9.6
putative N-acetyltransferase 9.4
SERPINB13 9.3
GODZ 9.3
CNN2 8.9
RNA polymerase II subunit 2 8.8
myosin-IC 8.6
DLK 8.5
cystatin SA 8.2
HLA B44 8.1
Coronin-1A 8.0
PPP1R13L 7.8
UBIAD1 7.8
GJB2 7.7
plakophilin 2 7.7
PAX6 protein 7.7
GRF2 7.7
immunoglobulin mu chain 7.6
TSLPR 7.6
HEYL 7.6
Cx30 7.5
GMPPB 7.5
NAT10 7.5
Interleukin 17A 7.5
HCE 7.4
RHS 7.4
corneal dystrophy 7.4
HIP-55 7.2
LCP1 7.2
CST6 7.1
Cx31.1 7.1
IL13RA2 7.1
SMILE 7.1
IFNA1 7.0
Jun dimerization protein 2 7.0
RCE1 7.0
Cx26 7.0
IL-17RC 7.0
NLRC3 6.9
thymocyte antigen 6.8
CPA2 6.8
HAI-2 6.7
keratan sulfate proteoglycan 6.7
Cx30.3 6.7
lamp 6.7
leukocyte interferon 6.7
transient receptor potential melastatin 6 6.6
PRK 6.6
UBE1 6.6
HUB 6.6
Pannexin 1 6.5
cathepsin V 6.5
laminin-binding protein 6.5
keratocan 6.4
aniridia 6.4
DG2 6.4
neutrophil protein 6.4
PAX6 6.4
choline dehydrogenase 6.4
RIG-1 6.3
tear lipocalin 6.3
SPINT2 6.3
cyl 6.3
cathepsin F 6.3
thymosin beta-4 6.2
macrophage inhibitory factor 6.2
TWIST2 6.2
P4HB 6.2
lacrimal 6.2
Con1 6.0
M-ficolin 6.0
PM5 6.0
more...
Disease
Superior rectus underaction 12.6
Herpes simplex disciform keratitis 12.6
keratoiritis 12.6
Adenoviral keratitis 12.6
Microsporidia keratitis 12.6
keratitis 12.6
Necrotizing conjunctivitis 12.6
Eosinophilic keratitis 12.6
Measles keratitis 12.6
Disciform keratitis 12.6
Simple episcleritis 12.6
Nodular episcleritis 12.6
Neurotrophic ulcer 12.6
Fungal keratitis 12.2
Bacterial keratitis 12.1
Stromal keratitis 12.1
Dendritic keratitis 12.0
Nummular keratitis 12.0
viral keratitis 11.9
kerato-uveitis 11.7
KID syndrome 11.7
Corneal infection 11.6
Recurrent herpetic keratitis 11.6
Filamentary keratitis 11.6
Rosacea keratitis 11.6
Corneal melt 11.6
Oculomycosis 11.6
Follicular conjunctivitis 11.6
Marginal keratitis 11.6
Nodular scleritis 11.6
Neuroparalytic keratitis 11.6
Necrotizing retinitis 11.6
Fungal corneal ulcer 11.6
superficial keratitis 11.4
Bart-Pumphrey syndrome 11.2
ocular herpes 11.1
Acanthamoeba keratitis 11.1
sclerokeratitis 11.0
Paecilomycosis 11.0
Corneal abscess 11.0
Atopic keratoconjunctivitis 10.9
Acanthamoeba infection 10.8
corneal ulcer 10.7
Neurotrophic keratopathy 10.6
Dennie-Morgan fold 10.6
Corneal hypoaesthesia 10.6
photophthalmia 10.6
Total ophthalmoplegia 10.6
Richner-Hanhart syndrome 10.5
Thygeson's superficial punctate keratitis 10.5
Exposure keratopathy 10.5
infectious conjunctivitis 10.4
Peripheral ulcerative keratitis 10.4
Phacolytic glaucoma 10.3
eye infection 10.1
Ocular siderosis 10.0
Naegleria meningoencephalitis 10.0
Mycobacterium chelonei infection 10.0
hypopyon 10.0
Bullous keratopathy 9.9
interstitial keratitis 9.9
blepharitis 9.8
Phlyctenular keratoconjunctivitis 9.8
tyrosinuria 9.8
iritis 9.8
lagophthalmos 9.8
Recurrent herpes simplex 9.7
herpes zoster ophthalmicus 9.7
pseudopterygium 9.6
Intraocular infection 9.6
bacterial conjunctivitis 9.5
scleritis 9.5
episcleritis 9.5
Salzmann 9.5
Corneal anesthesia 9.4
tyrosinosis 9.4
blepharoconjunctivitis 9.4
Epithelial ingrowth 9.4
Granulomatous amebic encephalitis 9.4
Recurrent corneal erosion 9.4
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Symptom
Sore eyes 12.6
Ophthalmalgia 11.6
bloodshot eyes 9.3
redness of the eyes 8.8
eye pain 8.6
photophobia 8.3
eye discharge 8.1
dry eye 8.0
localized erythema 7.6
polyopia 7.4
Roth spots 7.4
Koplik spots 7.3
blepharospasm 7.1
hemihypesthesia 7.0
scaly skin 6.8
blurred vision 6.6
Skin symptoms 6.5
hypalgesia 6.1
catarrh 6.0
No pain 5.8
Visual disturbances 5.8
periorbital edema 5.6
dysesthesia 5.5
generalized rash 5.4
jaw pain 5.1
adenitis 5.0
neuralgia 5.0
labored breathing 4.9
thinning 4.8
dry skin 4.6
ophthalmoplegia 4.5
Physical findings 4.2
microbial colonization 4.1
prostration 4.1
Scratch 4.0
erythema 3.8
nasal discharge 3.8
pallor 3.3
discomfort 3.3
discomfort 3.2
rhinorrhea 3.0
physical appearance 3.0
muscle cramps 2.8
DNA marker 2.7
hypoproteinemia 2.5
paresis 2.4
decreased appetite 2.4
facial pain 2.4
pain 2.3
paresthesia 2.3
fasciculation 2.3
numbness 2.3
vertigo 2.1
spasm 2.1
torticollis 1.9
enuresis 1.9
tinnitus 1.9
dysarthria 1.7
sneezing 1.7
neck pain 1.7
acute pain 1.6
hemiplegia 1.6
anesthesia 1.6
twitching 1.6
tense 1.5
myalgia 1.5
stridor 1.4
dizziness 1.4
dysuria 1.3
tachypnea 1.3
Ill 1.2
lethargy 1.1
HSA 1.1
bone pain 1.0
ataxia 1.0
flushing 1.0
spasticity 0.9
anorexia 0.8
analgesia 0.8
arthralgia 0.8
more...
Drug
Natacyn 12.0
Senofilcon A 11.6
Fluoroperm 92 11.6
Tobrex 11.4
Colistimethate 10.3
Tobi 10.2
Sodium cromoglicate 9.8
Zymar 9.8
Lodoxamide tromethamine 9.4
Ara-A 9.3
Habekacin 9.3
Neosporin 9.1
Sertaconazole 8.9
Tobramycin sulfate 8.8
Candicidin 8.8
Pranoprofen 8.6
Garamycin 8.5
Quantum II 8.4
Garamycin 8.1
Garamycin 8.1
Permalens 8.1
Zovirax 8.0
Mycostatin 8.0
Acuvue 7.9
Gramicidin D 7.9
Cortisporin 7.8
Cellcept 7.6
Cellcept 7.6
Acyclovir 7.5
Olopatadine hydrochloride 7.5
Cetrimide 7.4
Cortisporin 7.4
Pentamidine isethionate 7.4
Parsol 7.4
Travoprost 7.2
Tarivid 7.1
Cortisporin 7.0
TFT 6.9
CTZ 6.9
Bifonazole 6.8
Cortisporin 6.8
Solcoseryl 6.7
Gatifloxacin 6.7
Lamisil 6.4
Lamisil 6.4
Moxifloxacin 6.3
AC2 6.2
Timolol maleate 6.2
HPMPC 6.1
Bimatoprost 6.1
Mectizan 5.9
Ganciclovir 5.9
Methylcellulose 5.7
FCV 5.7
Caspofungin 5.7
Lugol's solution 5.6
Voltaren 5.6
Ofloxacin 5.5
Meditec 5.5
Acitretin 5.4
Span 60 5.3
Sodium hyaluronate 5.2
Cyanoacrylate 5.2
Ketoconazole 5.2
Posaconazole 5.1
Trimethoprim-sulfamethoxazole 5.0
Riboflavin 5.0
Deferasirox 5.0
Bactrim 4.9
Ranibizumab 4.9
Tocilizumab 4.9
Diclofenac sodium 4.9
Aztec 4.8
Poloxamer 188 4.8
Emodin 4.7
Miltefosine 4.7
PMEA 4.7
Anakinra 4.6
balanced salt solution 4.6
Geranium 4.6
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Enzyme
homoserine kinase 8.9
phospholipid:diacylglycerol acyltransferase 7.7
SMT1 7.3
staphopain 7.2
CPA2 6.8
cathepsin V 6.6
cathepsin F 6.6
serralysin 6.4
pseudolysin 6.4
choline dehydrogenase 6.3
lanosterol 14alpha-demethylase 6.3
tyrosine aminotransferase 6.1
nucleoside hydrolase 5.5
N-acetylgalactosaminidase 5.5
prostasin 5.4
phosphoribulokinase 5.2
4-hydroxyphenylpyruvate dioxygenase 4.8
RGP 4.8
MIP 4.7
MTD 4.4
thymidine kinase 4.3
matrix metalloproteinase 9 4.1
matriptase 4.1
beta-hydroxybutyrate dehydrogenase 4.0
legumain 4.0
ribonucleotide reductase 3.9
ribonucleotide reductase 3.9
LasR 3.8
lactonase 3.8
lysostaphin 3.7
matriptase 3.6
elastase 3.6
Hageman factor 3.6
ADPase 3.5
cholesterol oxidase 3.2
alpha-mannosidase 3.0
caspase-2 3.0
CFI 3.0
dihydropyrimidine dehydrogenase 2.9
caspase-2 2.9
interstitial collagenase 2.7
mannanase 2.7
lipoxygenase 2.7
thymidine phosphorylase 2.6
glyceraldehyde-3-phosphate dehydrogenase 2.5
glyceraldehyde-3-phosphate dehydrogenase 2.5
MDR 2.5
matrix metalloproteinase 2 2.4
15-lipoxygenase 2.4
N-acetyltransferase 2.4
glyceraldehyde-3-phosphate dehydrogenase 2.4
TAT 2.4
lecithin:cholesterol acyltransferase 2.4
collagenase 2.3
dihydropyrimidine dehydrogenase 2.3
transketolase 2.3
SPC 2.2
MDP 2.2
phosphoglucomutase 2.2
LPL 2.2
glyceraldehyde-3-phosphate dehydrogenase 2.1
beta-glucosidase 2.1
deoxyribonuclease 2.1
deoxyribonuclease 2.0
apyrase 2.0
glyceraldehyde-3-phosphate dehydrogenase 1.9
leucine aminopeptidase 1.9
beta-glucosidase 1.9
PRA 1.9
peroxidase 1.9
aconitase 1.8
arginase 1.7
phosphorylase 1.7
DNase 1.7
DCF 1.7
cathepsin L 1.7
chondroitinase 1.6
caspase-1 1.6
MMP 1.5
DNA polymerase 1.5
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Compound
Fluorometholone acetate 11.6
C15H26O 11.0
Hexomedine 11.0
Brolene 10.8
Natamycin 10.3
trimethoxymethane 10.0
Dimethyl itaconate 10.0
Trifluorothymidine 9.7
Rotundifolone 9.3
Vasocon 9.1
Ara-A 8.8
Sangivamycin 8.7
IDU 8.6
Cyclocytidine 8.6
Ara-T 8.4
Tetraphenylporphyrin 8.3
Azocasein 8.3
benzoyl isothiocyanate 8.1
Vidarabine 8.0
Adenine arabinoside 8.0
MIBT 7.9
TFT 7.9
Econazole 7.8
1H-phenalen-1-one 7.7
Rufloxacin 7.7
Betnesol 7.6
Econazole 7.6
Voriconazole 7.6
Metipranolol 7.4
Cetrimide 7.4
Acyclovir 7.4
Penciclovir 7.4
Diethylcarbamazine citrate 7.4
Salvarsan 7.3
Chlorhexidine diacetate 7.3
Tobramycin 7.3
Miconazole 7.3
C14H19N3O4 7.2
Chlorhexidine diacetate 7.0
stigmastane 7.0
PMEG 6.9
1-methyltryptophan 6.9
Alantolactone 6.8
Diethylcarbamazine 6.7
Palmatine 6.7
ara-AMP 6.7
isopropyl palmitate 6.7
ara-AMP 6.7
Suprofen 6.6
Exotoxin 6.6
Gentamicin sulfate 6.5
Azocoll 6.5
Valacyclovir 6.4
Lomefloxacin 6.4
Flubendazole 6.4
Cromolyn 6.2
Amentoflavone 6.2
Gatifloxacin 6.2
13-cis-Retinoic acid 6.2
Punicalagin 6.1
Moxifloxacin 6.1
Enoxacin 6.1
Cephaloridine 6.1
Primidone 6.0
terephthalamide 5.9
Amphotericin B 5.9
T11 5.8
Clotrimazole 5.7
Ofloxacin 5.7
Levofloxacin 5.7
Repaglinide 5.6
Amantadine 5.6
DHPG 5.5
PVP-I 5.5
Benzothiazole 5.5
Florid 5.4
TFF 5.4
Glimepiride 5.4
Caryophyllene 5.4
Solu-Medrol 5.4
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