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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Recent reports incriminating Acanthamoeba, a small free-living amoeba, wide-spread in environmental soils and waters, in acanthamoebic keratitis cases wearing soft contact lenses, drew attention to cleaning solutions for contact lenses. The purpose of this report is to discuss the amoebicidal action of a rinsing solution containing 0.001% thimerosal. A. castellanii cysts and trophozoites were incubated with the rinsing solution. Amoeba saline was used as control solution. After 1 h to 96 h of contact time, the survival was studied by growing of trophozoites and excystment of cysts on cultures. The results indicate that trophozoites were destroyed by the rinsing solution after 6 hours, whereas for cysts a negative culture was obtained after 72 h to 96 h. The amoebicidal and cysticidal action of this solution containing mercury corroborates our preceding experience on the effects of mercury derivates on amoebae. The use of amoebicidal solutions in contactology could inhibit and even destroy amoebae on contaminated lenses preventing severe keratitis.
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PMID:[Use of a rinsing solution for contact lenses in the prevention of amebic keratitis]. 304 62

Mycotic keratoconjuntivitis caused by Acremonium kiliense in a German Shepherd bitch was diagnosed with the aid of laboratory tests. The dog presented with photophobia, tearing, corneal edema and reduction of the visual capacity. A thick white layer partially covered the right eye. The left eye showed irritation and small brown stains which were diagnosed as pigmentary keratitis. The initial treatment consisted of 2% yellow mercury oxide. Natamycin was used as final treatment. Seven days later, the natural brightness of the eye as well as the visual capacity were restored.
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PMID:Canine mycotic keratoconjuntivitis caused by Acremonium kiliense. 409 50

We report an outbreak of keratoconjunctivitis and skin erythema caused by ultraviolet radiation from a damaged high-intensity mercury vapor lamp. Twenty-six persons became ill after using a basketball court; symptoms included conjunctivitis (100%), skin erythema (54%), and punctate keratitis (19%). This outbreak is one of 37 similar episodes involving at least 629 persons reported to the Food and Drug Administration since 1969. Physicians should be aware that damaged high-intensity mercury vapor lamps are a continuing public health problem with substantial morbidity. Measures to prevent such occurrences are suggested.
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PMID:Ocular complications of malfunctioning mercury vapor lamps. 718 32

Before the microbiologic era, venereal diseases were poorly distinguished. Congenital syphilis was believed to be transmitted during conception by the father's sperm, during delivery in the birth canal, or from infected milk or breasts. The most frequent maternofetal transmission was not considered because the mother's primary infection remained undiagnosed. The concept of treating infants with mercury transmitted by nurses' milk prompted the founding of a specialized infant hospital in Vaugirard in 1780: lactating syphilitic women received mercury orally and by rubbing it into the skin. Their own infant and a second infected infant from the foundling hospital were believed to be cured by their milk. Underwood described snuffles in 1789 and Bertin periosteal bone disease in 1810. Tardive congenital lues with keratitis, deafness, and notched upper incisors were described by Hutchinson in 1863. Feeding remained difficult, as wet nursing transmitted syphilis to the nurse and other infants. Specialized institutions tried goat or donkey milk. A debate between contagionists assuming exclusively maternal infection and hereditists assuming germinal transmission by the father's sperm continued throughout the 19th century. Schaudinn and Hoffmann identified Spirochaeta pallida in 1905. When Ehrlich discovered the efficacy of salvarsan in 1910, Noeggerath treated infants with the new drug, pioneering the injection into scalp veins. In 1943, Lentz and Ingraham established penicillin treatment for congenital syphilis. Whereas this drug effectively prevented maternofetal transmission, treating infants remained difficult due to the Jarisch-Herxheimer reaction.
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PMID:Curse on two generations: a history of congenital syphilis. 2348 62