Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Activities of four antioxidative enzymes (superoxide dismutase, glutathione reductase, catalase, and peroxidase) and of three transferases (serum glutamic oxaloacetic and pyruvic transaminases, gamma-glutamyl transpeptidase) were measured in the lacrimal fluid of patients with herpetic keratitis. Measurements of lacrimal enzymes in the course of the disease helps assess the efficacy of treatment and permits its correction. After the treatment of herpetic keratitis is over, activities of the lacrimal enzymes should be assessed together with clinical signs, this permitting a prediction of a recurrence of ophthalmic herpes and timely administration of anti-relapse treatment.
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PMID:[Enzymatic analysis of lacrimal fluid in viral keratitis]. 789 97

The purpose of the study was to develop a procedure for predicting a relapse of herpetic keratitis in children, by taking into account the results of tear biochemical analysis. The tears from 47 children with herpetic keratitis were examined for the levels of total protein, the concentration of acute-phase proteins, such as orosomucoid and C-reactive protein, the activities of transferases: gamma-glutamyltranspeptidase transferase, aspartate aminotransferase, and alanine aminotransferase, those of lysosomal glycosidases: alpha-mannosidase, beta-glycosidase, and beta-glucuronidase. Tear biochemical assay made it possible to evaluate the efficiency of treatment and to develop a procedure for predicting a recurrence of herpetic keratitis in children. Determination of the tear activity of the glycosidases may be used to predict recurrent herpetic keratitis in children.
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PMID:[Use of tear enzyme assay to predict recurrent herpetic keratitis in children]. 1780 56