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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Filamentary keratitis is characterized by the presence of fine filaments of epithelium and mucus that are attached to the cornea. The exact pathogenesis of this entity has remained unclear. One reason has been the lack of pathologic specimens of corneas from patients with filamentary keratitis. We examined the corneas of a patient who had died while suffering from filamentary keratitis. Scattered groups of inflammatory cells and fibroblasts were present just below the basal epithelium. It seemed that these cells had disrupted the epithelial basement membrane and Bowman's layer. To our knowledge, this is the first postmortem analysis of a cornea in a patient with acute filamentary keratitis. These findings support the theory that filamentary keratitis results from damage to the basal epithelial cells, epithelial basement membrane, or both.
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PMID:The histopathology of filamentary keratitis. 402 49

Filamentary keratitis is a problem associated with a wide variety of ocular conditions. Of 114 patients receiving penetrating keratoplasty, 31 (27.2%) were noted to have filaments. Those patients receiving transplants for keratoconus were noted to have the highest incidence (12 of 31, 39%), while transplants following herpetic scars were not associated with filaments (0 of 11) in this series. Suturing technique or relation of donor button-to-graft site were not apparently important factors in the development of postoperative filamentary keratitis.
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PMID:Filamentary keratitis following penetrating keratoplasty. 675 2