Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0022568 (
keratitis
)
5,133
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
When tested in guinea pigs, Y.
pseudotuberculosis
strains, serovar I (25 strains) and serovar V (1 strain), were found for the first time to be capable of causing keratoconjunctivitis in the animals; the most virulent of these strains caused progressive conjunctivitis and
keratitis
with generalized infection. The minimum infective dose was 10(4) for conjunctivitis and 10(6) for
keratitis
. The studied Y.
pseudotuberculosis
strains, serovars O3 and O9, were found to be incapable of causing conjunctivitis and
keratitis
. The authors believe that the keratoconjunctival test allows one to evaluate the invasiveness and toxicity of Y.
pseudotuberculosis
according to the degree of the manifestation and the time of the development of conjunctivitis and
keratitis
.
...
PMID:[Use of the keratoconjunctival test for determining the virulence of the causative agent of pseudotuberculosis]. 634 60
