Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this report, a case of bacterial keratitis caused by Klebsiella ozaenae is presented. The patient was an otherwise healthy 65-year-old woman with a history of chronic ocular inflammation and a corneal transplant two years prior to the appearance of the corneal ulcer. K. ozaenae is uncommon as a cause of keratitis and is recognized as a cause of atrophic rhinitis and as an opportunistic pathogen in patients with various underlying diseases. The organism was not identified with the computer-assisted API 20E for identification of the Enterobacteriaceae, and conventional methods were required to demonstrate its unique properties. The clinical spectrum of disease, the characteristics of the organism, and its susceptibility to antimicrobial agents are discussed.
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PMID:Isolation of Klebsiella ozaenae from a corneal abscess. 399 31

Three Parma wallabies (Macropus parma) were inoculated with a herpesvirus recovered from a captive Parma wallaby with fatal naturally-occurring disease. Two intravenously inoculated animals died after 5 days and one animal infected via the conjunctiva and nasal mucosa was killed when moribund at 7 days. An additional two wallabies held in contact with the others became infected; they were killed at 11 days, when one was severely affected and one was mildly affected. All had small vesicles and ulcers of the skin of the upper and lower lips, eyelids, anogenital area and adjacent genital mucosa. Small vesicles and ulcers and large ulcers, with adherent necrotic epithelium and inflammatory debris, were present on the mucosa of the upper lips and adjacent gums and the conjunctiva. Numerous large basophilic or eosinophilic intranuclear inclusion bodies were observed in the epithelial cells of these vesicles and ulcers and of adjacent hair follicles and sebaceous glands. There was a mild to moderately severe rhinitis. Keratitis was present in two wallabies. Liver lesions were present in two animals but were unlike those seen in herpesviral hepatitis in other species.
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PMID:Parma wallaby herpesvirus infection. 627 1