Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two quantitative pipette samples and 3 smears from each of 305 eyes were re-evaluated. Two types of ferning (F) were detected i.e. rectangular (FR) and acute-angled (FA) ramifications, respectively. One FR corresponds in area to 0.11 FA. Ferning was present in 29% of pipette samples, averaging 0.41 mm2 in the form of FR in the total series. Ferning was most frequent in samples with fairly large amounts of mucus, more frequent in neutrophilia than in lymphocytosis, and the rarest in normal cytology. F was seen in several cases of acute infections conjunctivitis (55%), neonatal and follicular conjunctivitis, and keratitis, whereas it was rare in normal eyes (7%). This distribution is presumably due to the amount of mucus in the samples preserving the F-pattern during the preparation procedure. F was rarely seen in smears (0.7%).
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PMID:Ferning in conjunctival-cytologic preparations. Crystallisation in stained semiquantitative pipette samples of conjunctival fluid. 357

A 10-year-old Thoroughbred gelding showed rapid weight loss over about 1 week. Clinically, it had increased respiration and heart rates, dark red mucous membranes with petechial haemorrhages, and a bilateral keratitis. Routine haematological examination showed a lymphocytosis with increased numbers of small hyperchromatic lymphocytes in circulation, but no anaemia. On necropsy, many enlarged abdominal lymph nodes were seen and there was a large amount of fluid in the peritoneal cavity and pericardial sac. Histopathologically, small lymphocytes in- filtrated most tissues including the bone marrow, lymph nodes, liver, gastrointestinal tract and cornea. These were identified as T-lymphocytes by the use of immunohistochemistry and CD3 (positive), CD20 (negative) and CD 79a (negative) markers. A T-cell lymphocytic leukaemia and multi-centric lymphoma with generalised tissue infiltration were therefore diagnosed.
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PMID:T-cell lymphocytic leukaemia and lymphoma in a horse (abstract). 1603 95