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Query: UMLS:C0022568 (keratitis)
 5,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Corneal edema occurring in the congenital rubella syndrome can result from coexistent glaucoma or develop in the absence of an elevated intraocular pressure. We examined a 36-week-old female infant with documented congenital rubella syndrome who had bilateral corneal stromal edema without attendant congenital glaucoma. Histopathologic examination of the cornea revealed absent Descemet's membrane, deep interstitial keratitis, stromal corneal swelling, and deranged, focally absent endothelial cells. A viral infiltration of endothelium is postulated as the mechanism of the corneal edema and keratitis.
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PMID:Persistent corneal edema in the congenital rubella syndrome. 668 49

Two compounds, bromovinyldeoxyuridine ([E]-5-[2-bromovinyl]-2'-deoxyuridine) and trifluridine (5-trifluoromethyl-2' deoxyuridine) were compared for their efficacy in the topical treatment of experimental stroma herpetic keratitis produced by the injection of live herpes simplex virus, type 1, into the corneal stroma of rabbits. The trifluridine was used as 1% eyedrops, whereas bromovinyldeoxyuridine was used as either 0.1% or 0.5% eyedrops. All three treatment regimens caused a substantial healing of stroma disease in comparison with placebo treatment. The bromovinyldeoxyuridine (whether used as 0.1% or 0.5%) proved superior to 1% trifluridine eyedrops when the treatment was started one day after virus inoculation. However, bromovinyldeoxyuridine and trifluridine were equally effective if the treatment was started seven days after infection. The 0.5% bromovinyldeoxyuridine eyedrops seemed to be more effective in controlling the complicating severe iritis and secondary glaucoma than either 0.1% bromovinyldeoxyuridine or 1% trifluridine. No toxic effects were observed with bromovinyldeoxyuridine in any eye, whereas 1% trifluridine produced punctate epitheliopathy in some eyes.
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PMID:Experimental stroma herpes simplex keratitis. Influence of treatment with topical bromovinyldeoxyuridine and trifluridine. 680 47

In severe zoster keratitis many pathogenic factors are involved. In addition to viral manifestations, the cornea is often affected by anterior uveitis or secondary glaucoma. Neuroparalytic keratitis causes lowered blinking frequency and decreased tear secretion. In addition, zoster ulcerations of the upper lid margin mechanically disturb reformation of the tear film and weaken the lipid layer by necrosis of the Meibomian glands. Ointments reduce break-up time and parasympathicolytic mydriatics further decrease tear secretion. When the average time between two blinks is shorter than the tear film break-up time, a "dry eye" condition usually develops. The appropriate treatment in such cases is thorough prevention of evaporation.
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PMID:[Diagnosis and treatment of neuroparalytic zoster keratitis (author's transl)]. 697 Aug 53

The different indications for penetrating keratoplasty are discussed on the basis of the clinical results of the past five years. Keratoconus is the most important group, followed by other corneal dystrophies, metaherpetic keratitis, graft failures and corneal scars. The results are very good in the first two groups, much less so in the last two. Eyes with repeated keratoplasty have a bad prognosis. One-half of the regrafts become cloudy. The most important postoperative complications, such as wound dehiscence, glaucoma, allograft reaction and anterior synechias are discussed.
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PMID:[Keratoplasty]. 701 53

Thirty-eight patients with ocular hypertension or glaucoma were treated with topical timolol for 12-30 months (mean 20). A long lasting hypotensive effect of timolol eyedrops was found. However a need to increase therapy during the follow-up period was noted especially in the glaucoma group. Eyes with pseudoexfoliations often required concomitant therapy from the beginning. Ocular side effects were relatively few but four cases of punctate keratitis and another two with decreased corneal sensitivity were observed.
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PMID:Timolol-maintenance treatment. 733 80

Report of six patients with corneal lesions due to abuse of local anesthetics. Depending on the duration and frequency of application of local anesthetics and individual disposition, the following lesions occur: superficial punctate keratitis, corneal erosions, edema of epithelium and stroma, stromal infiltrates, stromal defects, iritis, cataract, secondary glaucoma. During the prolonged period of healing following a stromal affection, bullae of the epithelium and erosions occur at these sites repeatedly in some cases; vascularization and leukoma may also occur. The most important local anesthetics currently in use are mentioned. Local anesthetics for the eye should only be administered by the physician.
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PMID:[Anesthetic keratitis (author's transl)]. 745 12

Eye diseases in 1028 children below 15 years of age, seen at the Eye clinic of the University College Hospital, Ibadan, Nigeria were studied. Refractive error, vernal conjunctivitis, measles keratitis associated with malnutrition and those referrable to injuries were leading causes of eye problems amongst children. Diseases of ocular adnexa (excluding orbital cellulitis) squints, glaucoma, uveitis and trachoma were rare.
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PMID:Childhood eye diseases in Ibadan. 760 46

Pain or redness of the eye are frequent symptoms of out patient ophthalmological visit. Diagnosis is based both on the patient symptoms and a careful eyeball examination. After an eye trauma, it is necessary to check the absence of corneal or subpalpebral foreign body, and the absence of an eyeball laceration or an intraocular foreign body. Without traumatism, pain or redness of the eye suggest an anterior segment pathology with various diagnosis: keratitis is mostly due to bacterial infection, a significant intraocular pressure elevation is frequently due to angle closure glaucoma or inflammation of the anterior uvea in case of iridocyclitis. When pain and redness of the eye are associated with visual impairment, it is mostly due to a severe ocular pathology. In that case an ophthalmological referral is mandatory.
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PMID:[Acute painful and red eyes]. 774 51

A retrospective review for bullous keratopathy in our hospital from 1985 to 1992 was studies. Among the cases with bullous keratopathy, 14 were performed with antiglaucoma operation and cataract extraction, 12 that experienced a contusion or penetrating trauma history underwent cataract operation. IOL implantation seen in 3 patients, 4 cases were associated with vitreous contact to cornea after cataract extraction, the other 4 cases had advanced glaucoma. Besides, there were 1 case of Fuch's endothelium dystrophy, ICE syndrome and severe herpes simplex keratitis, respectively. The preoperation visual acuity of them was all less than finger count. The follow-up was 3 months to 5 years. The results showed the grafts of 28 cases (70%) were clear, 7 cases (17.5%) semi-clear, 5 cases (12.5%) opaque. Postoperatively, all of the patients escaped from the pain and 22 cases achieved a visual acuity of 0.02-0.7. Some good advice in treatment of bullous keratopathy were proposed.
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PMID:[Penetrating keratoplasty for bullous keratopathy]. 777 1

Laser irradiation at subthreshold energies exerts various effects on the eye and other parts of the body, mainly the skin and nervous system, through a mechanism that has yet to be adequately explained. The ocular bioeffects are manifested mostly in the retina, but also in other ocular tissues. This review outlines the reported effects of low-energy laser irradiation on nonophthalmological tissues and organs, including those of the nervous system, with special emphasis on the optic nerve. It also details the ophthalmic phenomena induced by low-energy laser irradiation and examines claims of its therapeutic efficacy in several eye diseases, such as keratitis, glaucoma and macular degeneration.
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PMID:Ophthalmic effects of low-energy laser irradiation. 780 Dec 19


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