Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0022116 (
ischemia
)
91,303
document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
5931
Mol
4297
ATP
4143
CA1
2829
caspase-3
2002
superoxide dismutase
1886
cytokine
1488
lactate dehydrogenase
1307
tumor necrosis factor
1236
nitric oxide synthase
1156
Bcl-2
1138
vascular endothelial growth factor
1127
TNF
1073
catalase
1051
insulin
1028
creatine kinase
1005
myeloperoxidase
898
MRI
832
IL-6
797
GSH
768
inducible nitric oxide synthase
759
ATPase
743
ADP
700
xanthine oxidase
695
albumin
691
p38
678
penumbra
667
hemoglobin
656
endoplasmic reticulum
638
cytochrome c
630
glial fibrillary acidic protein
626
collagen
622
CA3
617
NMR
598
glutathione peroxidase
557
gut
554
NMDA receptor
538
axonal
533
ERK1
529
VEGF
522
heme oxygenase-1
516
AMP
505
calcium channel
495
SOD
486
aspartate aminotransferase
447
alanine aminotransferase
445
MAPK
442
TNF-alpha
440
endothelin-1
436
angiotensin II
431
lipopolysaccharide
427
PI3K
421
ROS
416
LDH
414
p53
412
ERK
397
NADH
393
bradykinin
389
vascular endothelium
379
TLR4
378
CO2
373
GABA
371
brain-derived neurotrophic factor
366
JNK
365
endothelial nitric oxide synthase
365
She
362
heat shock protein
354
IL-10
353
interleukin-6
350
erythropoietin
347
renin
346
calpain
345
HSP70
333
eNOS
333
OGD
321
tissue plasminogen activator
319
cyclooxygenase
310
thrombin
306
NAD
306
chemokine
304
more...
Disease
ischemia
91303
stroke
8226
cerebral ischemia
6472
myocardial ischemia
6238
myocardial infarction
4832
cold
2794
hypertension
2716
diabetes
2714
coronary artery disease
2690
depression
2069
heart failure
2040
acute myocardial infarction
1742
atherosclerosis
1692
cancer
1446
tumor
1319
renal ischemia
1126
ventricular fibrillation
1098
coronary occlusion
1096
sepsis
1041
sepsis
1008
Alzheimer's disease
928
cardiovascular disease
901
GSH
769
cerebral infarction
709
acute renal failure
705
brain edema
692
renal failure
613
hyperglycemia
609
unstable angina
593
heart disease
569
renal disease
563
gangrene
551
epilepsy
536
claudication
535
vascular disease
523
plaque
517
subarachnoid hemorrhage
506
NAME
490
encephalopathy
477
congestive heart failure
458
celiac disease
456
coronary heart disease
448
vasculitis
444
SEM
430
dementia
427
obesity
422
cardiomyopathy
412
paraplegia
411
neuropathy
363
Evans
349
Parkinson's disease
347
hypoglycemia
345
intermittent claudication
341
cognitive impairment
339
preeclampsia
323
peripheral vascular disease
321
ventricular hypertrophy
319
intraocular pressure
308
type 2 diabetes
303
diabetic retinopathy
302
transient ischemic attack
297
glaucoma
293
compartment syndrome
280
bowel obstruction
272
retinopathy
272
Ischemic stroke
263
abdominal aortic aneurysm
262
pulmonary edema
255
aortic aneurysm
251
liver disease
247
arteriosclerosis
245
anemia
244
pulmonary hypertension
233
coma
230
migraine
229
hypercholesterolemia
229
blindness
227
cirrhosis
219
hyperlipidemia
218
multiple sclerosis
217
more...
Symptom
pain
2131
angina
2065
functional recovery
1628
hypothermia
1565
anesthesia
1300
chest pain
918
seizures
888
abdominal pain
649
spasm
376
headache
309
collapse
277
fatigue
256
diarrhea
221
weakness
214
hypercapnia
184
vomiting
181
hyperoxia
176
thinning
153
starvation
144
syncope
142
dyspnea
140
nausea
139
analgesia
131
respiratory distress
128
discomfort
106
flushing
106
discomfort
105
vertigo
104
acute abdomen
98
paraparesis
97
paresthesia
89
dizziness
88
exhaustion
85
numbness
82
paresis
82
acute abdominal pain
74
exertional angina
73
pallor
65
asynergy
65
hemiplegia
60
colic
57
cyanosis
55
tinnitus
53
ataxia
51
Anoxia
51
back pain
51
constipation
50
oliguria
49
shortness of breath
46
atypical chest pain
46
acidity
46
regurgitation
46
erythema
45
epigastric pain
43
tremor
42
nausea and vomiting
42
memory loss
42
leg pain
41
myalgia
39
acute stress
38
spasticity
37
hypocapnia
36
anorexia
34
dysarthria
33
acute pain
32
neurological disability
30
lethargy
30
agitation
29
livedo
29
distraction
29
hemoptysis
28
overweight
28
exertional dyspnea
27
intestinal angina
26
cough
25
neck pain
25
ophthalmoplegia
24
incoordination
23
limb pain
20
polyuria
20
more...
Drug
Cardiovasc
3731
ROS
416
NADH
396
nitroglycerin
381
vitamin E
248
ascorbate
238
TTC
219
CSF
174
Monit
146
MAP
130
Heme
128
lysine
127
Nephron
124
caffeine
115
Dermatol
104
Ringer's solution
99
Fluorescein
86
Adenosine triphosphate
83
Indomethacin
83
Angiotensin II
80
IFN-gamma
78
Nitric Oxide
75
Portal
69
Nephron
67
Dial
67
Fluorescein
64
Propofol
63
IL-2
62
Iloprost
62
Glutathione
58
Ranolazine
53
TAT
53
Ranolazine
53
ETA
51
EE2
50
Albumin
50
citric acid
49
Ethanol
47
Captopril
43
ICI
43
Parkin
42
Parkin
42
p75
40
Vitamin E
40
CPR
40
Histamine
39
G-CSF
38
CaCl2
37
BH4
36
Cilostazol
36
ROC
35
CaCl2
35
CaCl2
35
CTA
34
Glucagon
33
Simvastatin
33
uPA
32
MgSO4
31
Tacrolimus
31
FAD
31
APD
30
CTX
30
Methylprednisolone
30
TAK
28
balanced salt solution
27
Gel
27
Rosiglitazone
26
Sodium nitroprusside
26
CoCl2
26
CoCl2
26
Amiloride
25
Amiloride
25
Ouabain
24
Fructose
24
Leaf
23
Ginseng
23
Clopidogrel
22
EPI
21
Urokinase
21
Atropine
20
more...
Enzyme
superoxide dismutase
2182
mitogen-activated protein kinase
1638
caspase-3
1568
lactate dehydrogenase
1386
creatine kinase
1315
catalase
1108
peroxidase
1063
protein kinase
924
protein kinase C
915
ATPase
803
alanine aminotransferase
790
xanthine oxidase
706
ERK
702
aspartate aminotransferase
649
NO synthase
596
glutathione peroxidase
570
tissue plasminogen activator
449
renin
346
AMP-activated protein kinase
334
PARP
323
NADPH oxidase
301
NOS
300
thrombin
296
NADPH oxidase
268
luciferase
262
GSK
245
complex I
240
phosphodiesterase
232
ACE
229
focal adhesion kinase
229
phospholipase A2
212
phosphatidylinositol 3-kinase
206
AST
204
calcineurin
195
MEK
191
heme oxygenase
189
urokinase-type plasminogen activator
171
proteasome
170
succinate dehydrogenase
168
AMPK
162
caspase-9
161
glutathione reductase
149
cytochrome oxidase
143
APC
143
AMPK
141
guanylate cyclase
138
pyruvate dehydrogenase
126
collagenase
123
caspase-8
122
caspase-1
122
xanthine dehydrogenase
118
adenylate cyclase
117
ATP synthase
115
ACS
114
alkaline phosphatase
113
phospholipase C
111
lipoxygenase
108
CaMKII
106
pyruvate dehydrogenase
105
pyruvate dehydrogenase
105
MAP
104
adenosine deaminase
104
adenosine deaminase
103
reverse transcriptase
103
acetylcholinesterase
100
CAD
99
CAD
99
CAD
99
phosphoinositide 3-kinase
92
glutathione S-transferase
85
kallikrein
85
thromboplastin
81
tyrosine hydroxylase
77
ornithine decarboxylase
75
trypsin
75
MIP
75
monoamine oxidase
74
diaphorase
72
glyceraldehyde-3-phosphate dehydrogenase
68
CPR
67
more...
Compound
oxygen
11335
Dec
6181
calcium
5090
Cardiol
4896
glucose
4716
ATP
4148
Clin
3823
nitric oxide
2990
sodium
2634
glutamate
2485
water
2311
DNA
2023
potassium
1754
phosphate
1717
Cereb
1493
creatinine
1457
arginine
1106
hydrogen
1102
TNF
1073
nitrogen
894
CO2
839
Hearts
822
Hearts
815
GSH
807
GSH
807
ADP
805
iron
734
ADP
700
ADP
700
phosphocreatine
685
urea
608
AMP
542
H2O2
538
dUTP
525
prostacyclin
519
NMDA
491
acetate
474
Neuronal
451
Adenosine
448
NAD
416
His
408
cysteine
399
tyrosine
396
NADH
395
GABA
373
GABA
372
zinc
363
nitrate
349
ethanol
347
iodine
340
cAMP
337
cGMP
310
alanine
306
NAD
306
Glutamate
306
serine
304
Lactate
287
MDA
286
nicotinamide
273
salt
272
galactose
256
TTC
255
noradrenaline
246
sulfate
245
N-acetylcysteine
245
phosphorus
231
glutamine
223
AMPA
223
MTT
219
Melatonin
217
glycerol
203
Mg2+
203
superoxide radical
198
H2S
195
PEG
189
leucine
187
copper
182
MCA
182
MCA
181
gamma-aminobutyric acid
178
more...