Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022116 (ischemia)
91,303 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 5931
Mol 4297
ATP 4143
CA1 2829
caspase-3 2002
superoxide dismutase 1886
cytokine 1488
lactate dehydrogenase 1307
tumor necrosis factor 1236
nitric oxide synthase 1156
Bcl-2 1138
vascular endothelial growth factor 1127
TNF 1073
catalase 1051
insulin 1028
creatine kinase 1005
myeloperoxidase 898
MRI 832
IL-6 797
GSH 768
inducible nitric oxide synthase 759
ATPase 743
ADP 700
xanthine oxidase 695
albumin 691
p38 678
penumbra 667
hemoglobin 656
endoplasmic reticulum 638
cytochrome c 630
glial fibrillary acidic protein 626
collagen 622
CA3 617
NMR 598
glutathione peroxidase 557
gut 554
NMDA receptor 538
axonal 533
ERK1 529
VEGF 522
heme oxygenase-1 516
AMP 505
calcium channel 495
SOD 486
aspartate aminotransferase 447
alanine aminotransferase 445
MAPK 442
TNF-alpha 440
endothelin-1 436
angiotensin II 431
lipopolysaccharide 427
PI3K 421
ROS 416
LDH 414
p53 412
ERK 397
NADH 393
bradykinin 389
vascular endothelium 379
TLR4 378
CO2 373
GABA 371
brain-derived neurotrophic factor 366
JNK 365
endothelial nitric oxide synthase 365
She 362
heat shock protein 354
IL-10 353
interleukin-6 350
erythropoietin 347
renin 346
calpain 345
HSP70 333
eNOS 333
OGD 321
tissue plasminogen activator 319
cyclooxygenase 310
thrombin 306
NAD 306
chemokine 304
more...
Disease
ischemia 91303
stroke 8226
cerebral ischemia 6472
myocardial ischemia 6238
myocardial infarction 4832
cold 2794
hypertension 2716
diabetes 2714
coronary artery disease 2690
depression 2069
heart failure 2040
acute myocardial infarction 1742
atherosclerosis 1692
cancer 1446
tumor 1319
renal ischemia 1126
ventricular fibrillation 1098
coronary occlusion 1096
sepsis 1041
sepsis 1008
Alzheimer's disease 928
cardiovascular disease 901
GSH 769
cerebral infarction 709
acute renal failure 705
brain edema 692
renal failure 613
hyperglycemia 609
unstable angina 593
heart disease 569
renal disease 563
gangrene 551
epilepsy 536
claudication 535
vascular disease 523
plaque 517
subarachnoid hemorrhage 506
NAME 490
encephalopathy 477
congestive heart failure 458
celiac disease 456
coronary heart disease 448
vasculitis 444
SEM 430
dementia 427
obesity 422
cardiomyopathy 412
paraplegia 411
neuropathy 363
Evans 349
Parkinson's disease 347
hypoglycemia 345
intermittent claudication 341
cognitive impairment 339
preeclampsia 323
peripheral vascular disease 321
ventricular hypertrophy 319
intraocular pressure 308
type 2 diabetes 303
diabetic retinopathy 302
transient ischemic attack 297
glaucoma 293
compartment syndrome 280
bowel obstruction 272
retinopathy 272
Ischemic stroke 263
abdominal aortic aneurysm 262
pulmonary edema 255
aortic aneurysm 251
liver disease 247
arteriosclerosis 245
anemia 244
pulmonary hypertension 233
coma 230
migraine 229
hypercholesterolemia 229
blindness 227
cirrhosis 219
hyperlipidemia 218
multiple sclerosis 217
more...
Symptom
pain 2131
angina 2065
functional recovery 1628
hypothermia 1565
anesthesia 1300
chest pain 918
seizures 888
abdominal pain 649
spasm 376
headache 309
collapse 277
fatigue 256
diarrhea 221
weakness 214
hypercapnia 184
vomiting 181
hyperoxia 176
thinning 153
starvation 144
syncope 142
dyspnea 140
nausea 139
analgesia 131
respiratory distress 128
discomfort 106
flushing 106
discomfort 105
vertigo 104
acute abdomen 98
paraparesis 97
paresthesia 89
dizziness 88
exhaustion 85
numbness 82
paresis 82
acute abdominal pain 74
exertional angina 73
pallor 65
asynergy 65
hemiplegia 60
colic 57
cyanosis 55
tinnitus 53
ataxia 51
Anoxia 51
back pain 51
constipation 50
oliguria 49
shortness of breath 46
atypical chest pain 46
acidity 46
regurgitation 46
erythema 45
epigastric pain 43
tremor 42
nausea and vomiting 42
memory loss 42
leg pain 41
myalgia 39
acute stress 38
spasticity 37
hypocapnia 36
anorexia 34
dysarthria 33
acute pain 32
neurological disability 30
lethargy 30
agitation 29
livedo 29
distraction 29
hemoptysis 28
overweight 28
exertional dyspnea 27
intestinal angina 26
cough 25
neck pain 25
ophthalmoplegia 24
incoordination 23
limb pain 20
polyuria 20
more...
Drug
Cardiovasc 3731
ROS 416
NADH 396
nitroglycerin 381
vitamin E 248
ascorbate 238
TTC 219
CSF 174
Monit 146
MAP 130
Heme 128
lysine 127
Nephron 124
caffeine 115
Dermatol 104
Ringer's solution 99
Fluorescein 86
Adenosine triphosphate 83
Indomethacin 83
Angiotensin II 80
IFN-gamma 78
Nitric Oxide 75
Portal 69
Nephron 67
Dial 67
Fluorescein 64
Propofol 63
IL-2 62
Iloprost 62
Glutathione 58
Ranolazine 53
TAT 53
Ranolazine 53
ETA 51
EE2 50
Albumin 50
citric acid 49
Ethanol 47
Captopril 43
ICI 43
Parkin 42
Parkin 42
p75 40
Vitamin E 40
CPR 40
Histamine 39
G-CSF 38
CaCl2 37
BH4 36
Cilostazol 36
ROC 35
CaCl2 35
CaCl2 35
CTA 34
Glucagon 33
Simvastatin 33
uPA 32
MgSO4 31
Tacrolimus 31
FAD 31
APD 30
CTX 30
Methylprednisolone 30
TAK 28
balanced salt solution 27
Gel 27
Rosiglitazone 26
Sodium nitroprusside 26
CoCl2 26
CoCl2 26
Amiloride 25
Amiloride 25
Ouabain 24
Fructose 24
Leaf 23
Ginseng 23
Clopidogrel 22
EPI 21
Urokinase 21
Atropine 20
more...
Enzyme
superoxide dismutase 2182
mitogen-activated protein kinase 1638
caspase-3 1568
lactate dehydrogenase 1386
creatine kinase 1315
catalase 1108
peroxidase 1063
protein kinase 924
protein kinase C 915
ATPase 803
alanine aminotransferase 790
xanthine oxidase 706
ERK 702
aspartate aminotransferase 649
NO synthase 596
glutathione peroxidase 570
tissue plasminogen activator 449
renin 346
AMP-activated protein kinase 334
PARP 323
NADPH oxidase 301
NOS 300
thrombin 296
NADPH oxidase 268
luciferase 262
GSK 245
complex I 240
phosphodiesterase 232
ACE 229
focal adhesion kinase 229
phospholipase A2 212
phosphatidylinositol 3-kinase 206
AST 204
calcineurin 195
MEK 191
heme oxygenase 189
urokinase-type plasminogen activator 171
proteasome 170
succinate dehydrogenase 168
AMPK 162
caspase-9 161
glutathione reductase 149
cytochrome oxidase 143
APC 143
AMPK 141
guanylate cyclase 138
pyruvate dehydrogenase 126
collagenase 123
caspase-8 122
caspase-1 122
xanthine dehydrogenase 118
adenylate cyclase 117
ATP synthase 115
ACS 114
alkaline phosphatase 113
phospholipase C 111
lipoxygenase 108
CaMKII 106
pyruvate dehydrogenase 105
pyruvate dehydrogenase 105
MAP 104
adenosine deaminase 104
adenosine deaminase 103
reverse transcriptase 103
acetylcholinesterase 100
CAD 99
CAD 99
CAD 99
phosphoinositide 3-kinase 92
glutathione S-transferase 85
kallikrein 85
thromboplastin 81
tyrosine hydroxylase 77
ornithine decarboxylase 75
trypsin 75
MIP 75
monoamine oxidase 74
diaphorase 72
glyceraldehyde-3-phosphate dehydrogenase 68
CPR 67
more...
Compound
oxygen 11335
Dec 6181
calcium 5090
Cardiol 4896
glucose 4716
ATP 4148
Clin 3823
nitric oxide 2990
sodium 2634
glutamate 2485
water 2311
DNA 2023
potassium 1754
phosphate 1717
Cereb 1493
creatinine 1457
arginine 1106
hydrogen 1102
TNF 1073
nitrogen 894
CO2 839
Hearts 822
Hearts 815
GSH 807
GSH 807
ADP 805
iron 734
ADP 700
ADP 700
phosphocreatine 685
urea 608
AMP 542
H2O2 538
dUTP 525
prostacyclin 519
NMDA 491
acetate 474
Neuronal 451
Adenosine 448
NAD 416
His 408
cysteine 399
tyrosine 396
NADH 395
GABA 373
GABA 372
zinc 363
nitrate 349
ethanol 347
iodine 340
cAMP 337
cGMP 310
alanine 306
NAD 306
Glutamate 306
serine 304
Lactate 287
MDA 286
nicotinamide 273
salt 272
galactose 256
TTC 255
noradrenaline 246
sulfate 245
N-acetylcysteine 245
phosphorus 231
glutamine 223
AMPA 223
MTT 219
Melatonin 217
glycerol 203
Mg2+ 203
superoxide radical 198
H2S 195
PEG 189
leucine 187
copper 182
MCA 182
MCA 181
gamma-aminobutyric acid 178
more...